Peptide Synthesis Market: Industry Trends and Global Forecasts, Till 2035: Distribution by Type of Peptide Synthesis Method (Chemical Synthesis and Non-Chemical Synthesis), Type of Chemical Synthesis (Solid Phase Peptide Synthesis, Liquid Phase Peptide Synthesis and Hybrid Phase Peptide Synthesis), Contract Manufacturing Organization Size (Small, Mid-sized, and Large Companies), Key Geographical Regions (North America, Europe, and Asia-Pacific and Rest of the World)
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The peptide synthesis market is valued at USD 2.5 billion in 2023 growing at a CAGR of 5.46% during the forecast period 2023-2035.
Peptides serve as signaling molecules that bind to specific receptors on cell surfaces, initiating intracellular effects that regulate physiological functions and metabolic synthesis of various components. Their significance as therapeutic candidates have grown due to enhanced metabolic stability, target specificity, and affinity. Unlike small molecule drugs and biologics, peptide-based therapeutics present unique challenges in pharmacological research, analytical/process development, impurity research, and structure recognition. The peptide synthesis market has evolved significantly in recent years, driven by the popularity of peptide therapeutics. Currently, over 80 peptide therapeutics have been approved globally for treating various chronic diseases such as cancer, chronic pain, diabetes, HIV infection, multiple sclerosis, and osteoporosis. Moreover, since 2015, more than 630 clinical trials have been underway to evaluate the therapeutic effectiveness of peptide-based therapies. Further, the increasing research activity and demand for peptide-based treatments have led developers to expand their capabilities and upgrade manufacturing equipment. However, peptide synthesis faces challenges including production capacity shortages, prompting developers to outsource complex manufacturing processes to contract service providers to reduce costs and time to market. Pharmaceutical and biotechnology companies are actively collaborating with contract manufacturing organizations (CMOs) offering advanced technology platforms to improve the bioavailability of peptide drugs and enhance synthesis efficacy. Outsourcing demand surged with the entry of semaglutide generics into the peptide synthesis market. GLP-1 peptide API contract manufacturing demand notably rose at a rate of 37% annually during 2017-2023 due to its benefits in treating metabolic disorders like type II diabetes and obesity. These factors present lucrative opportunities for contract manufacturers in the peptide synthesis market in the near future.

Key Market Segments
Type of Synthesis Method Used
?Chemical Synthesis Method
?Non-Chemical Synthesis Method
Type of Chemical Synthesis Method
?Liquid Phase Peptide Synthesis
?Solid Phase Peptide Synthesis
?Hybrid Phase Peptide Synthesis
Company (CMO) Size
?Small
?Mid-sized
?Large
Geography
?North America
?Europe
?Asia-Pacific and Rest of the World
Research Coverage:
?The report studies the peptide synthesis market based on type of synthesis method used, type of chemical synthesis method, company (CMO) size and key geographical regions
?The report assesses the potential advantages and obstacles within the market for those involved and offers information on the competitive environment for top players in the market.
?The report forecasts the revenue of market segments with respect to three major regions
?A comprehensive examination of the current market landscape of contract manufacturers providing peptide synthesis services, including various pertinent parameters such as establishment year, entry year into peptide API manufacturing, company size (number of employees), headquarters location, product type (API, intermediates, FDF / fill-finish), API type, services offered, peptide synthesis method, peptide modification type, purification technology, regulatory certifications, geographical presence, and location of peptide API manufacturing facilities.
?Detailed company competitiveness evaluation of peptide synthesis contract manufacturers, considering supplier strength and company competitiveness in terms of type of API, type of service offered, type of synthesis method, purification technique used, scale of operation and geographical presence. In addition, number of peptide modification services offered has also been considered. A comprehensive review of recent developments and initiatives undertaken by contract manufacturers in the peptide synthesis industry. This includes a focus on partnerships, collaborations, and expansion initiatives occurring in the peptide synthesis market from 2014 to October 2023.
?An in-depth analysis of ongoing and planned studies concentrating on peptide therapeutics. This analysis encompasses various parameters such as trial registration year, number of enrolled patients, trial phase, status, study design (masking type, intervention model, primary purpose), sponsor/collaborator type, therapeutic area, mechanism of action, clinical trial centers, geography, and patient population.
?A detailed examination of the capabilities of peptide synthesis companies in different regions. This analysis considers parameters like the number of Contract Manufacturing Organizations (CMOs), clinical sites, clinical trials, enrolled patients, peptide manufacturing facilities, demand for peptide therapeutics, and installed capacity.
?Informed estimates of the annual commercial and clinical demand for peptide therapeutics based on parameters such as target patient population, dosing frequency, and dose strength.
?An estimate of the global installed capacity of contract manufacturers in the peptide synthesis market. This analysis considers data reported by industry stakeholders and factors in the distribution of peptide production capacity among companies of different sizes (small, mid-sized, and large), operational scale (preclinical/clinical and commercial), location of manufacturing facility (North America, Europe, and Asia Pacific), and synthesis method (solid phase peptide synthesis and liquid phase peptide synthesis).
?An analysis highlighting potential strategic partners based on the likelihood of collaborating with peptide therapeutics developers. These potential partners are shortlisted considering parameters like pipeline strength, pipeline maturity, year of establishment, and company size.
?A qualitative examination outlining the key factors that peptide drug developers must consider when deciding whether to produce their products in-house or enlist the services of a Contract Manufacturing Organization (CMO).
?An in-depth, region-specific analysis of the total cost of ownership associated with engaging a peptide contract manufacturing service provider. This analysis provides an estimate of both direct and indirect expenses across 10 relevant parameters over a 20-year timeframe.
?A review of regulatory guidelines pertaining to peptide synthesis, with a focus on the variations observed across different regions such as the US, Europe, Australia, China, India, Japan, and South Korea. This discussion also addresses the regulatory challenges faced by peptide synthesis companies.
?A discourse on industry-related trends, key drivers, and challenges within the peptide synthesis sector, structured within a SWOT framework. This analysis includes a Harvey ball assessment to highlight the relative impact of each SWOT parameter on industry dynamics.

Key Benefits of Buying this Report
?The report offers market leaders and newcomers valuable insights into revenue estimations for both the overall market and its sub-segments.
?Stakeholders can utilize the report to enhance their understanding of the competitive landscape, allowing for improved business positioning and more effective go-to-market strategies.
?The report provides stakeholders with a pulse on the peptide synthesis market, furnishing them with essential information on significant market drivers, barriers, opportunities, and challenges.
Key Market Companies
?AmbioPharm
?CPC Scientific
?Creative Peptides
?CSBio
?Bachem
?BCN Peptide
?CordenPharma
?Senn Chemicals
?PolyPeptide
?Auspep
?Chinese Peptide Company
?Hybio Pharmaceuticals
?Peptide Institute
?ScinoPharm