Market Overview
The Global Proanthocyanidins Market is expected to grow at a high CAGR of 6.2% during the forecasting period (2023-2030).
Proanthocyanidins are the oligomeric flavonoids that are the dimers or oligomers of catechin and epicatechin and their gallic acid esters. Proanthocyanidins have beneficial health effects as these are effective for reducing the risk of cancer. Proanthocyanidins provide a beneficial effect on heart health and blood vessels. These flavonoids are rich in antioxidants that are useful for maintaining healthy blood pressure levels. Proanthocyanidins are comprised of cleansing properties and protecting the skin cells from the ultraviolet rays, prevent scar formation, and improve blood circulation.

Market Dynamics
The market is driven by the rising demand for the proanthocyanidins in personal cosmetic, healthcare, pet nutrition, functional food and beverage industries as the proanthocyanidins provide therapeutic and health benefits
Proanthocyanidins also have antioxidant characteristics. The Proanthocyanidins improve bone strength, cure healing wounds, reduce skin-related diseases, including skin cancer, and provide cardiovascular benefits. Proanthocyanidins are useful for reducing the intensity of abdominal pain in chronic pancreatitis. Proanthocyanidins help in lowering the cholesterol levels, preventing ulcer formation, and protecting the digestive and urinary systems.
The rising prevalence of lifestyle-related diseases including diabetes and cardiovascular conditions is boosting the further demand for the proanthocyanidins. The proanthocyanidins reduce blood pressure among people suffering from hypertension. Various studies have demonstrated the efficacy of the proanthocyanidins for reducing the progression of diabetic retinopathy or vision loss.
The increase in the launch of the products comprising the Proanthocyanidins stimulates market growth. For instance, in August 2018, Activ’Inside had launched an organic grape seed extract guaranteed with the highest level in OPC, Grape’ Inside 60P CO, part of the Signature grape Activ’Inside has developed a unique organic OPC grape seed extract with the highest amount of Oligomer Proanthocyanidins (OPC) range.
However, the high price of proanthocyanidins and lower market penetration is hindering the market growth. The lack of awareness among the consumers regarding the benefits of proanthocyanidins also has a negative impact on the market.

COVID-19 Impact Analysis
The COVID-19 pandemic has disrupted the global economy and halted the key processes of almost all companies. Therefore, even the global proanthocyanidins market suffered due to it. The disturbances in supply chain management and transportation of goods and services had a negative impact on the growth of the market. Many manufacturing and production units were disrupted due to the government enforced lockdowns and curfews across the world which lead to losses and wastage of many proanthocyanidin products. The pandemic also significantly changed the consumer demand and behaviour. Consumers refrained from purchasing non-essential products amid the pandemic thereby impacting the sales of proanthocyanidins-based nutritional supplements. The uncertain and unexpected situation caused by the pandemic significantly impacted the market hence, slowing its growth. However, the post-pandemic scene has improved and the proanthocyanidin market has recovered. The market is set to grow at a high rate due to the various benefits of proanthocyanidin products, especially its anti-cancer properties.

Segment Analysis
The global proanthocyanidins market is segmented based on product type as Type A and Type B
Type B segment accounted for the highest market share in 2019. Type B proanthocyanidins have a higher proportion of the B-type linkages in their chemical structure which are very useful in countering many health defects. The type B proanthocyanidins are found in pine bark, grape seed, apples, and cocoa. These proanthocyanidins help in improving the blood flow, night vision, and reduce iron levels in cases of excess iron build-up in the body. Type B proanthocyanidins are beneficial for improving bone strength & formation. These proanthocyanidins help in preventing the infection by protecting from the various pathogens. They also exhibit anti-inflammatory and antioxidant properties.
The Type A segment is expected to grow at a high CAGR owing to the increasing usage of the Type A proanthocyanidins for various applications including pharmaceuticals, personal care, cosmetics, and food supplements. The cranberry is rich in the Type A proanthocyanidins. It is beneficial for maintaining urinary tract health. Type-A proanthocyanidins exhibit potent bacterial anti-adhesion activities that are useful for maintaining personal hygiene, hence leading to its projected growth.
Further, the market is also classified based on the source as cranberry, grape seeds, pine bark, and others
The cranberry segment accounts for the highest market share as the cranberries are the major source of the proanthocyanidins especially the Type-A proanthocyanidins. The proanthocyanidins found in the cranberry comprised of different structures than those found in other fruits and vegetables. These proanthocyanidins exhibit the anti-adhesion properties that are useful for preventing the adhesion of certain harmful bacteria, including E. coli associated with urinary tract infections, onto the cell walls.
The grape seeds segment is expected to grow at a positive rate over the forecasted period. The proanthocyanidins obtained through grape seeds are a rich source of vitamins P & E, linoleic acid, and resveratrol. The grape seed proanthocyanidins exhibit excellent cleansing properties and protect the skin cells. These proanthocyanidins help in protecting nerve cells from damage. The grape seed proanthocyanidins are useful for lowering the severity of nasal allergies by decreasing the production of histamine.
Geographical Presentation
By region, the global proanthocyanidins market is segmented into North America, South America, Europe, Asia-Pacific, Middle-East and Africa
Among all of the regions, North America dominated the global proanthocyanidins market and is expected to grow at a high CAGR during the forecasted period owing to the high consumption of the proanthocyanidins due to their anti-angiogenic, anti-microbial and anti-cancer properties. There is growing awareness regarding the health and therapeutic benefits of proanthocyanidins. There is increasing usage of the proanthocyanidins in the food and beverage industry. The United States accounted for the highest share in 2019 due to the high daily intake of proanthocyanidins as dietary supplements. The rising advancement in the dietary supplement industry shall stimulate market growth.
The Asia-Pacific region is expected to have a positive market growth due to the growing consumption of healthy food with the growing aging population. There is increasing usage of proanthocyanidins for pharmaceuticals. The increasing domestic income and purchasing power of people shall boost the demand for proanthocyanidins.
Competitive Analysis
The global proanthocyanidins market is highly competitive with the presence of several international and local markets. Product diversification, revenue generation, and opportunities intensify the market competition. Naturex, Indena Spa, Nexira, Scott Laboratories Inc., Polyphenolics, Natac Group, Eevia Health, and Botaniex Inc. are the leading market players with significant market share.
The major players are using product launches, market expansion, and product diversification strategies for holding their position in the market. The companies are entering into collaborations, mergers, strategic partnerships, and acquisitions to increase the demand for Proanthocyanidins and their expansion across the globe. For instance, in September 2018, French nutraceutical ingredient manufacturer Nexira had entered into a strategic partnership with California Natural Color, a supplier of natural color crystals & concentrates for the development of the completely natural grape seed extract, which is extracted with water rather than chemical solvents. This collaboration would allow the company to provide unique customer offerings and exploit the growing market for procyanidins in the supplements industry. In April 2021, Nexira and Quadra Ingredients are announced that they have entered into a distribution agreement in Canada. The partnership of these two Ingredient Powerhouses will bring excellent opportunities and a real technical expertise to customers.
Naturex
Overview: It is a botanicals company which has expertise in plant extraction and development of natural ingredients for developing efficient solutions for the food, health and beauty sectors.
Product Portfolio: It produces and sells plant extracts for flavouring, colouring and preservative purposes in the food industry.
Key Developments: In June 2020, Naturex introduced Ultimine Zinc, which is the world’s first wholefood fermented zinc for immune health support.
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