Protein A resins market is projected to record a substantial growth rate over the coming years owing to the increasing research and development activities in the healthcare sector. Protein A resin is an affinity chromatography resin with superior binding capacity for lgG. It is suitable for purification of polyclonal antibodies, monoclonal antibodies, and immunology complexes like Co-IP and IP.

Protein A resins offers multiple advantages such as superior capacity vs. flow rate performance with the chemical and physical stability of a rigid polymeric support. They deliver enhanced throughput without increasing column size, and is optimized for very rapid mass transport.

The protein A resin market is segmented in terms of application, product, matrix type, end use, and regional landscape.

Based on application, the market is bifurcated into immunoprecipitation and antibody purification. Immunoprecipitation is used to precipitate protein antigen using an antibody which is deactivated to a solid support like agarose resin or magnetic particles. Immunoprecipitation is one of the most commonly used methods for segregation of proteins as well as other biomolecules from tissue or cell lysates for the objective of subsequent discovery by western blotting and other assay techniques.

With respect to product, the market is classified into natural protein A and recombinant protein A. Among these, natural protein A has a higher capacity of antibody purification.

Based on matrix type, the market is categorized into silica or glass gel-based matrix, agarose-based matrix, and organic polymer-based matrix. Among these, agarose-based matrix has high gelling strength at low concentrations, suitable pH range, and anti-convection medium for gel electrophoresis.

It is one of the two main components of agar and is also purified by eliminating its other component, that is agaropectin. Agarose is often used in molecular biology for the separation of large molecules, specially DNA by electrophoresis.

For the purpose of chromatography, agarose is widely considered the best available material for protein purification resins. Presently several therapeutic antibodies are purified with agarose-based matrix.

With respect to end-use, the market is bifurcated into academic research institutes, biopharmaceutical companies, contract research organizations, and clinical research laboratories. Among these, contract research organizations are witnessing growth owing to increasing research & development activities and growing trend of outsourcing large-scale production.

From a regional frame of reference, the Asia-Pacific protein A resins market is set to observe growth due to rising drug discovery & development and rising demand for immunotherapy drugs for treating chronic diseases.