Global active pharmaceutical ingredients market will reach $334 billion by 2028, growing by 6.9% annually over 2021-2028, driven by rising adoption of biologics in disease management, increasing regulatory approvals, patent expiration of major drugs, growing trend of outsourcing and increase in geriatric population.

Highlighted with 146 tables and 104 figures, this 254-page report “Global Active Pharmaceutical Ingredients (API) Market 2021-2028 by Synthesis (Synthetic, Biotech, HPAPI), Manufacturing Process (Captive, Merchant), Therapeutic Application, Drug Type, and Region: Trend Forecast and Growth Opportunity” is based on a comprehensive research of the entire global active pharmaceutical ingredients market and all its sub-segments through extensively detailed classifications. Profound analysis and assessment are generated from premium primary and secondary information sources with inputs derived from industry professionals across the value chain. The report is based on studies on 2018-2021 and provides forecast from 2022 till 2028 with 2021 as the base year. (Please note: The report will be updated before delivery so that the latest historical year is the base year and the forecast covers at least 5 years over the base year.)

In-depth qualitative analyses include identification and investigation of the following aspects:

  • Market Structure
  • Growth Drivers
  • Restraints and Challenges
  • Emerging Product Trends & Market Opportunities
  • Porter’s Fiver Forces


The trend and outlook of global market is forecast in optimistic, balanced, and conservative view by taking into account of COVID-19. The balanced (most likely) projection is used to quantify global active pharmaceutical ingredients market in every aspect of the classification from perspectives of Synthesis, Manufacturing Process, Therapeutic Application, Drug Type, and Region.

Based on Synthesis, the global market is segmented into the following sub-markets with annual revenue ($ bn) for 2018-2028 included in each section.

Synthetic API

  • Branded Synthetic API
  • Generic Synthetic API


Biotech API by Drug Type:

  • Monoclonal Antibodies
  • Recombinant Proteins
  • Vaccines
  • Other Biotech APIs


Biotech API by Customer Base:

  • Innovative Biologic API
  • Generic Biosimilar API


Biotech API by Expression Technology:

  • Mammalian Expression
  • Microbial Expression
  • Yeast Expression
  • Insect Expression
  • Other Expression Technologies

HPAPI
  • Branded HPAPI
  • Generic HPAPI



Based on Manufacturing Process, the global market is segmented into the following sub-markets with annual revenue ($ bn) for 2018-2028 included in each section.

Captive Manufacturing

  • Branded Captive API
  • Generic Captive API


Merchant Manufacturing by Drug Type:

  • Branded Merchant API
  • Generic Merchant API


Merchant Manufacturing by Drug Synthesis:

  • Merchant Synthetic API
  • Merchant Biotech API



By Therapeutic Application, the global market is segmented into the following sub-markets with annual revenue ($ bn) for 2018-2028 included in each section.

  • Infectious Diseases
  • Oncology
  • Ophthalmology
  • Cardiovascular Disorders
  • Central Nervous System
  • Pulmonary Disorders
  • Orthopedics
  • Other Applications



By Drug Type, the global market is segmented into the following sub-markets with annual revenue ($ bn) for 2018-2028 included in each section.

  • Branded Prescription Drugs
  • Generic Prescription Drugs
  • OTC Drugs



Geographically, the following regions together with the listed national/local markets are fully investigated:

  • North America (U.S., Canada, and Mexico)
  • Europe (Germany, UK, France, Spain, Italy, Russia, Rest of Europe; Rest of Europe is further segmented into Netherlands, Switzerland, Poland, Sweden, Belgium, Austria, Ireland, Norway, Denmark, and Finland)
  • APAC (Japan, China, South Korea, Australia, India, and Rest of APAC; Rest of APAC is further segmented into Indonesia, Malaysia, New Zealand, Singapore, Thailand, and Vietnam)
  • South America (Brazil, Chile, Argentina, Rest of South America)
  • MEA (UAE, Saudi Arabia, South Africa, Other Nations)


For each aforementioned region and country, detailed analysis and data for annual revenue ($ bn) are available for 2018-2028. The breakdown of all regional markets by country and split of key national markets by Synthesis, Manufacturing Process, and Therapeutic Application, over the forecast years are also included.

The report also covers current competitive scenario and the predicted trend; and profiles key vendors including market leaders and important emerging players.

Selected Key Players:

  • AbbVie Inc.
  • Astrazeneca
  • Aurobindo Pharma Ltd.
  • BASF
  • Bayer AG
  • Boehringer Ingelheim
  • Catalent Inc.
  • Dr. Reddy’s Laboratories
  • F. Hoffmann-La Roche
  • GlaxoSmithKline plc
  • Lonza Group
  • Lupin Limited
  • Merck & Co., Inc.
  • Mylan NV
  • Novartis International AG
  • Pfizer Inc.
  • Sanofi
  • Sun Pharmaceutical Industries Ltd.
  • Teva Pharmaceutical Industries Ltd.
  • Thermo Fisher Scientific

(Please note: The report will be updated before delivery so that the latest historical year is the base year and the forecast covers at least 5 years over the base year.)