3D Cell Culture Market by Product (Scaffold-based, Scaffold-free, Microfluidics-based, and Magnetic & Bioprinter), Application (Cancer, Stem Cell, Toxicology, Tissue Engineering), End-User (Pharmaceutical & Biotechnology Companies, Research Institutes, and Cosmetics Industry), By Geography (North America, Europe, APAC, and RoW) Global Opportunity Analysis and Industry Forecast up to 2026
A 3D cell culture is an artificial environment where biological cells grow or connect with their surrounding habitats in three dimensions. It develops types of different cells and tissues formulation which is not feasible under 2D culture systems. It has more properties of tissue mutation and cell cohesion. The early-stage drug discovery and other related research have earned 3D cell structure increasing popularity which can be seen in its growing application.
Research Methodology:
The 3D cell culture market has been analyzed by utilizing the optimum combination of secondary sources and in-house methodology, along with an irreplaceable blend of primary insights. The real-time assessment of the market is an integral part of our market sizing and forecasting methodology. Our industry experts and panel of primary participants have helped in compiling relevant aspects with realistic parametric estimations for a comprehensive study. The participation share of different categories of primary participants is given below:

3D cell culture is growing at a fast pace in the healthcare environment because of the significant scale of implementations in various areas like cancer research, vitro environment, and regenerative medicine. It has the potential to understand tissue maturation and formation, organogenesis, and cell differentiation has increased its utility. Now animal prototypes in clinical testing and experiments are replaced because of its similarity with cells in vivo. The 3D cell culture market is majorly driven through the increasing usage of 3D cell culture in diagnostic centers, hospitals, pharmaceutical, and biotech companies. Which directly increases the demand for organ transplantation, tissue regeneration, and regenerative medicine.
The research report segregates the market into the following segments:
By Product
Scaffold-based 3D Cell Cultures
Hydrogels/ECM Analogs
Solid Scaffolds
Micropatterned Surfaces
Scaffold-free 3D Cell Cultures
Low Attachment Plates
Hanging Drop Plates
3D Bioreactors
3D Petri Dishes
Microfluidics-based 3D Cell Cultures
Magnetic & Bioprinted 3D Cell Cultures
By Application
Cancer & Stem Cell Research
Drug Discovery & Toxicology Testing
Tissue Engineering & Regenerative Medicine
By End User
Pharmaceutical & Biotechnology Companies
Research Institutes
Cosmetics Industry
Other End Users
Some of the prominent companies in the area of 3D Cell Culture are:
3D Biotek, LLC
Advanced Biomatrix, Inc
Dickinson and Company
Corning Incorporated
Kuraray Co., Ltd
Lonza Group Ltd
Merck & Co., Inc
Synthecon Incorporated
Thermo Fisher Scientific Inc
VWR Corporation.

The report also contains insight regarding technological innovations and advanced solutions for the 3D Cell Culture. The study also gives an in-depth idea about the major competitors in the market, their journey and the competitive edge via systematic analytical tools including SWOT analysis. As per Infoholic Research, the estimated market value of 3D Cell Culture in 2020 is US$ 2,717.6 million and it is predicted that it will grow at a CAGR of 29.1%. There are three important factors which are the driving forces behind the growth of 3D Cell Culture market:

The key features which have fueled its increased its growth are:

The rise in the prevalence rate of cancer
Growing Focus on Personalized Medicine
High Degree of Corporate Inclusion for Research

The physiologic, histologic, and functional properties of the respective tissues have given the homotypic and heterotypic 3D tissue culture models. These properties enhance the different cellular functions such as adhesion, migration, gene expression, and proliferation. The creation of duct-like structures in vitro environments can be formed by two important factors such as normal polarization and differentiation of epithelial cells as well as with the usage of 3D cultures. Moreover, the synergistic effect required for the interactions of cell-cell and cell-extracellular matrix (ECM), which can control the expression of molecules involved in cell differentiation, is also achieved in 3D cell cultures.
The potential that 3D models have so that it can minimize the accompanying flaws with 2D monolayer cultures is predetermined to fuel the demand for these techniques in the near future. The rising demand from the shift of 2D to 3D technology is pushing the growth of this market. In addition, opportunistic marketing competitors are entering this segment due to its high market potential. Subsequently, this will further propel the market.
These technologies provide advanced tools that can help to explore key aspects of disease and enable demonstration of micro-environmental factors that support in-vivo tumor growth. 3D concept of artificial cell cultivation provides vast benefits in the analysis of phenotypic heterogeneity of cancers and heterotypic intercellular crosstalk for 3D Cell Culture vendors to fulfill both the residential as well as commercial sectors.