Table of Content

1. Introduction To Molecular Switches
1.1 Overview
1.2 History & Emergence In Medicine


2. Molecular Switches Clinical Significance In Medicine


3. Molecular Switches Significance In Drug Delivery & Release
3.1 Overview
3.2 Ongoing Research & Developments


4. Molecular Switches Significance As Therapeutic Targets


5. Molecular Switches - Broad Classification


6. Molecular Switches By Cancer Indication
6.1 Breast Cancer
6.2 Prostate Cancer
6.3 Colorectal cancer
6.4 Lung Cancer
6.5 Gastric Cancer


7. Molecular Switches By Neurological Disorder
7.1 Parkinson’s Disease
7.2 Alzheimer’s Disease
7.3 Multiple Sclerosis


8. Molecular Switches By Infectious Disease
8.1 Viral Infection
8.2 Bacterial Infection



9. Molecular Switches By Autoimmune & Inflammatory Disorder
9.1 Diabetes
9.2 Arthritis
9.3 Lupus
9.4 Psoriasis


10. Molecular Switches By Cardiovascular Disease
10.1 Myocardial Infarction (Heart Attack)
10.2 Others


11. Molecular Switches Significance In Regenerative Medicine


12. Sales Insight Of Key Drugs Targeting Molecular Switches


13. Molecular Switches In Drug Formulation
13.1 Smart Drug Formulations & Molecular Switches
13.2 Biomaterial Based Drug Delivery Systems
13.3 Self Regulating Drug Systems


14. Current Trends & Emerging Technologies
14.1 Molecular Switches In Nanomedicine
14.2 Innovations In Responsive Drug Systems
14.3 Integration With Artificial Intelligence & Machine Learning


15. Future Perspectives & Directions
15.1 Advancements In Molecular Switch Technology
15.2 The Future Of Personalized Medicine With Molecular Switches
15.3 Potential Impact On Drug Discovery & Therapeutics



List of Figures

Figure 1-1: Molecular Switches - Introduction
Figure 1-2: Molecular Switches – Emergence & Evolution

Figure 3-1: Molecular Switches In Drug Delivery & Release
Figure 3-2: Drug Delivery Systems With Molecular Switches
Figure 3-3: Peptide-Based Drug Delivery System
Figure 3-4: Switchable Molecular Tweezers
Figure 3-5: Rotaxane-Based Drug Delivery System
Figure 3-6: Enzyme-Activatable Drug Delivery System
Figure 3-7: Light-Responsive Drug Delivery Systems
Figure 3-8: Photo-Responsive Drug Delivery Using Spiropyran
Figure 3-9: Photopharmacological Approach For Neuropathic Pain
Figure 3-10: Insulin Prodrug Activation

Figure 6-1: AR Activation & Its Dual Role In Tumor Growth
Figure 6-2: PRL-3 Activation & AMPI-109’s Impact On TNBC
Figure 6-3: Molecular Switch in Prostate Cancer

Figure 7-1: PINK1-Parkin Molecular Switch In Parkinson’s Disease

Figure 8-1: Molecular Switches In Viral infections

Figure 11 1: Molecular Switches In Regenerative Medicine

Figure 13-1: Smart Drug Delivery With Molecular Switches
Figure 13-2: Biomaterial Based Drug Delivery Systems With Molecular Switches
Figure 13-3: Self-regulating Drug Systems With Molecular Switches

Figure 14-1: Molecular Switches In Nanomedicine
Figure 14-2: Molecular switches In Responsive Drug Systems
Figure 14-3: Integration Of Molecular Switches With Artificial Intelligence & Machine Learning

List of Tables

Table 1-1: Traditional v/s Molecular Switch Enabled Drug Delivery
Table 4-1: Examples Of Approved Drugs Targeting Molecular Switches
Table 5-1: Molecular Switches - Broad Classification
Table 12-1: Top 20 Drugs Targeting Molecular Switches (US$ Billion), 2022-2024