Table of Content


1 Introduction 9
1.1 Industry Definition and Research Scope 9
1.1.1 Industry Definition 9
1.1.2 Research Scope 10
1.2 Research Methodology 13
1.2.1 Overview of Market Research Methodology 13
1.2.2 Market Assumption 14
1.2.3 Secondary Data 14
1.2.4 Primary Data 14
1.2.5 Data Filtration and Model Design 15
1.2.6 Market Size/Share Estimation 16
1.2.7 Research Limitations 17
1.3 Executive Summary 18

2 Market Overview and Dynamics 21
2.1 Market Size and Forecast 21
2.1.1 Impact of COVID-19 on World Economy 23
2.1.2 Impact of COVID-19 on the Market 27
2.1.3 Impact of Russia-Ukraine Conflict 29
2.1.4 Impact of Israel-Palestine War 31
2.2 Major Growth Drivers 32
2.3 Market Restraints and Challenges 37
2.4 Emerging Opportunities and Market Trends 40
2.5 Porter’s Fiver Forces Analysis 43

3 Segmentation of Global Market by Product 47
3.1 Market Overview by Product 47
3.2 Prophylactic Vaccines 50
3.3 Therapeutic Vaccines 51
3.4 Therapeutic Drugs 52

4 Segmentation of Global Market by mRNA Type 53
4.1 Market Overview by mRNA Type 53
4.2 Self-amplifying mRNA 56
4.3 Nucleoside-modified mRNA 57
4.4 Unmodified mRNA 58

5 Segmentation of Global Market by Application 59
5.1 Market Overview by Application 59
5.2 Oncology 62
5.2.1 Personalized Treatment 63
5.2.2 Single Cancer Treatment 64
5.3 Respiratory Diseases 65
5.4 Infectious Diseases 66
5.5 Autoimmune Diseases 67
5.6 Rare Genetic Diseases 68
5.7 Other Applications 69

6 Segmentation of Global Market by End User 70
6.1 Market Overview by End User 70
6.2 Hospitals and Clinics 73
6.3 Research Organizations 74
6.4 Other End Users 75

7 Segmentation of Global Market by Region 76
7.1 Geographic Market Overview 2023-2033 76
7.2 North America Market 2023-2033 by Country 81
7.2.1 Overview of North America Market 81
7.2.2 U.S. 85
7.2.3 Canada 88
7.2.4 Mexico 90
7.3 European Market 2023-2033 by Country 92
7.3.1 Overview of European Market 92
7.3.2 Germany 96
7.3.3 U.K. 98
7.3.4 France 100
7.3.5 Spain 102
7.3.6 Italy 104
7.3.7 Russia 106
7.3.8 Rest of European Market 108
7.4 Asia-Pacific Market 2023-2033 by Country 110
7.4.1 Overview of Asia-Pacific Market 110
7.4.2 Japan 114
7.4.3 China 117
7.4.4 Australia 119
7.4.5 India 121
7.4.6 South Korea 123
7.4.7 Rest of APAC Region 125
7.5 South America Market 2023-2033 by Country 127
7.5.1 Argentina 131
7.5.2 Brazil 133
7.5.3 Colombia 135
7.5.4 Rest of South America Market 137
7.6 MEA Market 2023-2033 by Country 138
7.6.1 UAE 142
7.6.2 Saudi Arabia 144
7.6.3 Israel 146
7.6.4 Other National Markets 148

8 Competitive Landscape 149
8.1 Overview of Key Vendors 149
8.2 New Product Launch, Partnership, Investment, and M&A 153
8.3 Company Profiles 154
Arcturus Therapeutics 154
Argos Therapeutics Inc. 156
AstraZeneca Plc 157
BioNTech SE 158
CRISPR Therapeutics AG 159
CureVac AG 160
eTheRNA 161
Ethris GMBH 162
GlaxoSmithKline PLC 163
Moderna Therapeutics Inc. 164
Pfizer Inc. 165
Sangamo Therapeutics Inc. 166
Translate Bio Inc. 167

9 Investing in mRNA Therapeutics Industry: Risk Assessment and Management 168
9.1 Risk Evaluation of Global Market 168
9.2 Critical Success Factors (CSFs) 174
RELATED REPORTS 177



List of Figures


List of Figures:

Figure 1. Research Method Flow Chart 13
Figure 2. Bottom-up Approach and Top-down Approach for Market Estimation 16
Figure 3. Global Market Forecast in Optimistic, Conservative and Balanced Perspectives, 2023-2033 18
Figure 4. Industry Value Chain Analysis 21
Figure 5. Global mRNA Therapeutics Market, 2023-2033, $ mn 22
Figure 6. Impact of COVID-19 on Business 27
Figure 7. Primary Drivers and Impact Factors of Global mRNA Therapeutics Market 32
Figure 8. Worldwide Geriatric Population (60 years and above) by Regions, 2015 & 2030, million 35
Figure 9. World Population 65 and Over, % of Total Population, 1950-2060 35
Figure 10. Primary Restraints and Impact Factors of Global mRNA Therapeutics Market 37
Figure 11. Porter’s Fiver Forces Analysis of Global mRNA Therapeutics Market 43
Figure 12. Growth Opportunity Analysis by Product 47
Figure 13. Breakdown of Global mRNA Therapeutics Market by Product, 2023-2033, % of Revenue 48
Figure 14. Global Addressable Market Cap in 2024-2033 by Product, Value ($ mn) and Share (%) 49
Figure 15. Global mRNA Therapeutics Market by Product: Prophylactic Vaccines, 2023-2033, $ mn 50
Figure 16. Global mRNA Therapeutics Market by Product: Therapeutic Vaccines, 2023-2033, $ mn 51
Figure 17. Global mRNA Therapeutics Market by Product: Therapeutic Drugs, 2023-2033, $ mn 52
Figure 18. Growth Opportunity Analysis by mRNA Type 53
Figure 19. Breakdown of Global mRNA Therapeutics Market by mRNA Type, 2023-2033, % of Sales Revenue 54
Figure 20. Global Addressable Market Cap in 2024-2033 by mRNA Type, Value ($ mn) and Share (%) 55
Figure 21. Global mRNA Therapeutics Market by mRNA Type: Self-amplifying mRNA, 2023-2033, $ mn 56
Figure 22. Global mRNA Therapeutics Market by mRNA Type: Nucleoside-modified mRNA, 2023-2033, $ mn 57
Figure 23. Global mRNA Therapeutics Market by mRNA Type: Unmodified mRNA, 2023-2033, $ mn 58
Figure 24. Growth Opportunity Analysis by Application 59
Figure 25. Breakdown of Global mRNA Therapeutics Market by Application, 2023-2033, % of Sales Revenue 60
Figure 26. Global Addressable Market Cap in 2024-2033 by Application, Value ($ mn) and Share (%) 61
Figure 27. Global mRNA Therapeutics Market by Application: Oncology, 2023-2033, $ mn 62
Figure 28. Global mRNA Therapeutics Market by Oncology: Personalized Treatment, 2023-2033, $ mn 63
Figure 29. Global mRNA Therapeutics Market by Oncology: Single Cancer Treatment, 2023-2033, $ mn 64
Figure 30. Global mRNA Therapeutics Market by Application: Respiratory Diseases, 2023-2033, $ mn 65
Figure 31. Global mRNA Therapeutics Market by Application: Infectious Diseases, 2023-2033, $ mn 66
Figure 32. Global mRNA Therapeutics Market by Application: Autoimmune Diseases, 2023-2033, $ mn 67
Figure 33. Global mRNA Therapeutics Market by Application: Rare Genetic Diseases, 2023-2033, $ mn 68
Figure 34. Global mRNA Therapeutics Market by Application: Other Applications, 2023-2033, $ mn 69
Figure 35. Growth Opportunity Analysis by End User 70
Figure 36. Breakdown of Global mRNA Therapeutics Market by End User, 2023-2033, % of Revenue 71
Figure 37. Global Addressable Market Cap in 2024-2033 by End User, Value ($ mn) and Share (%) 72
Figure 38. Global mRNA Therapeutics Market by End User: Hospitals and Clinics, 2023-2033, $ mn 73
Figure 39. Global mRNA Therapeutics Market by End User: Research Organizations, 2023-2033, $ mn 74
Figure 40. Global mRNA Therapeutics Market by End User: Other End Users, 2023-2033, $ mn 75
Figure 41. Global Market Snapshot by Region 76
Figure 42. Growth Opportunity Analysis of Global Market by Region 77
Figure 43. Geographic Spread of Worldwide mRNA Therapeutics Market, 2023-2033, % of Sales Revenue 78
Figure 44. Global Addressable Market Cap in 2024-2033 by Region, Value ($ mn) and Share (%) 79
Figure 45. North American mRNA Therapeutics Market, 2023-2033, $ mn 82
Figure 46. Growth Opportunity Analysis of North America Market by Country 82
Figure 47. Breakdown of North America mRNA Therapeutics Market by Country, 2023 and 2033, % of Revenue 83
Figure 48. Contribution to North America 2024-2033 Cumulative Market by Country, Value ($ mn) and Share (%) 84
Figure 49. U.S. mRNA Therapeutics Market, 2023-2033, $ mn 86
Figure 50. Canada mRNA Therapeutics Market, 2023-2033, $ mn 88
Figure 51. mRNA Therapeutics Market in Mexico, 2023-2033, $ mn 90
Figure 52. European mRNA Therapeutics Market, 2023-2033, $ mn 93
Figure 53. Growth Opportunity Analysis of Europe Market by Country 93
Figure 54. Breakdown of European mRNA Therapeutics Market by Country, 2023 and 2033, % of Revenue 94
Figure 55. Contribution to Europe 2024-2033 Cumulative Market by Country, Value ($ mn) and Share (%) 95
Figure 56. mRNA Therapeutics Market in Germany, 2023-2033, $ mn 96
Figure 57. mRNA Therapeutics Market in U.K., 2023-2033, $ mn 98
Figure 58. mRNA Therapeutics Market in France, 2023-2033, $ mn 100
Figure 59. mRNA Therapeutics Market in Spain, 2023-2033, $ mn 102
Figure 60. mRNA Therapeutics Market in Italy, 2023-2033, $ mn 104
Figure 61. mRNA Therapeutics Market in Russia, 2023-2033, $ mn 106
Figure 62. mRNA Therapeutics Market in Rest of Europe, 2023-2033, $ mn 108
Figure 63. Asia-Pacific mRNA Therapeutics Market, 2023-2033, $ mn 111
Figure 64. Growth Opportunity Analysis of Asia-Pacific Market by Country 111
Figure 65. Breakdown of APAC mRNA Therapeutics Market by Country, 2023 and 2033, % of Revenue 112
Figure 66. Contribution to APAC 2024-2033 Cumulative Market by Country, Value ($ mn) and Share (%) 113
Figure 67. mRNA Therapeutics Market in Japan, 2023-2033, $ mn 115
Figure 68. mRNA Therapeutics Market in China, 2023-2033, $ mn 117
Figure 69. mRNA Therapeutics Market in Australia, 2023-2033, $ mn 119
Figure 70. mRNA Therapeutics Market in India, 2023-2033, $ mn 121
Figure 71. mRNA Therapeutics Market in South Korea, 2023-2033, $ mn 123
Figure 72. mRNA Therapeutics Market in Rest of APAC, 2023-2033, $ mn 125
Figure 73. South America mRNA Therapeutics Market, 2023-2033, $ mn 128
Figure 74. Growth Opportunity Analysis of South America Market by Country 128
Figure 75. Breakdown of South America mRNA Therapeutics Market by Country, 2023 and 2033, % of Revenue 129
Figure 76. Contribution to South America 2024-2033 Cumulative Market by Country, Value ($ mn) and Share (%) 130
Figure 77. mRNA Therapeutics Market in Argentina, 2023-2033, $ mn 131
Figure 78. mRNA Therapeutics Market in Brazil, 2023-2033, $ mn 133
Figure 79. mRNA Therapeutics Market in Colombia, 2023-2033, $ mn 135
Figure 80. mRNA Therapeutics Market in Rest of South America, 2023-2033, $ mn 137
Figure 81. mRNA Therapeutics Market in Middle East and Africa (MEA), 2023-2033, $ mn 139
Figure 82. Growth Opportunity Analysis of MEA Market by Country 139
Figure 83. Breakdown of MEA mRNA Therapeutics Market by Country, 2023 and 2033, % of Revenue 140
Figure 84. Contribution to MEA 2024-2033 Cumulative Market by Country, Value ($ mn) and Share (%) 141
Figure 85. mRNA Therapeutics Market in UAE, 2023-2033, $ mn 142
Figure 86. mRNA Therapeutics Market in Saudi Arabia, 2023-2033, $ mn 144
Figure 87. mRNA Therapeutics Market in Israel, 2023-2033, $ mn 146
Figure 88. mRNA Therapeutics Market in the Rest of MEA, 2023-2033, $ mn 148
Figure 89. Growth Stage of Global mRNA Therapeutics Industry over the Forecast Period 149
Figure 90. Comparison of Risk Factors by GMD RIN in 2023 171
Figure 91. GMD Relative RIN of Internal Risk Factors in 2023 on Radar Chart 172
Figure 92. GMD Relative RIN of External Risk Factors in 2023 on Radar Chart 172

List of Tables


List of Tables:

Table 1. Snapshot of Global mRNA Therapeutics Market in Balanced Perspective, 2023-2033 19
Table 2. World Economic Outlook, 2024-2036 24
Table 3. World Economic Outlook, 2022-2024 26
Table 4. Scenarios for Economic Impact of Ukraine Crisis 30
Table 5. Scenarios for Economic Impact of Israel-Palestine War 31
Table 6. World Health Spending by Region, $ bn, 2013-2020 36
Table 7. Main Product Trends and Market Opportunities in Global mRNA Therapeutics Market 40
Table 8. Global mRNA Therapeutics Market by Product, 2023-2033, $ mn 48
Table 9. Global mRNA Therapeutics Market by mRNA Type, 2023-2033, $ mn 54
Table 10. Global mRNA Therapeutics Market by Application, 2023-2033, $ mn 60
Table 11. Global mRNA Therapeutics Market: Oncology by Type, 2023-2033, $ mn 62
Table 12. Global mRNA Therapeutics Market by End User, 2023-2033, $ mn 71
Table 13. Global mRNA Therapeutics Market by Region, 2023-2033, $ mn 78
Table 14. Leading National mRNA Therapeutics Market, 2023 and 2033, $ mn 80
Table 15. North America mRNA Therapeutics Market by Country, 2023-2033, $ mn 83
Table 16. U.S. mRNA Therapeutics Market by Product, 2023-2033, $ mn 87
Table 17. U.S. mRNA Therapeutics Market by Application, 2023-2033, $ mn 87
Table 18. U.S. mRNA Therapeutics Market by End User, 2023-2033, $ mn 87
Table 19. Canada mRNA Therapeutics Market by Product, 2023-2033, $ mn 89
Table 20. Canada mRNA Therapeutics Market by Application, 2023-2033, $ mn 89
Table 21. Canada mRNA Therapeutics Market by End User, 2023-2033, $ mn 89
Table 22. Mexico mRNA Therapeutics Market by Product, 2023-2033, $ mn 91
Table 23. Mexico mRNA Therapeutics Market by Application, 2023-2033, $ mn 91
Table 24. Mexico mRNA Therapeutics Market by End User, 2023-2033, $ mn 91
Table 25. Europe mRNA Therapeutics Market by Country, 2023-2033, $ mn 94
Table 26. Germany mRNA Therapeutics Market by Product, 2023-2033, $ mn 97
Table 27. Germany mRNA Therapeutics Market by Application, 2023-2033, $ mn 97
Table 28. Germany mRNA Therapeutics Market by End User, 2023-2033, $ mn 97
Table 29. U.K. mRNA Therapeutics Market by Product, 2023-2033, $ mn 99
Table 30. U.K. mRNA Therapeutics Market by Application, 2023-2033, $ mn 99
Table 31. U.K. mRNA Therapeutics Market by End User, 2023-2033, $ mn 99
Table 32. France mRNA Therapeutics Market by Product, 2023-2033, $ mn 101
Table 33. France mRNA Therapeutics Market by Application, 2023-2033, $ mn 101
Table 34. France mRNA Therapeutics Market by End User, 2023-2033, $ mn 101
Table 35. Spain mRNA Therapeutics Market by Product, 2023-2033, $ mn 103
Table 36. Spain mRNA Therapeutics Market by Application, 2023-2033, $ mn 103
Table 37. Spain mRNA Therapeutics Market by End User, 2023-2033, $ mn 103
Table 38. Italy mRNA Therapeutics Market by Product, 2023-2033, $ mn 105
Table 39. Italy mRNA Therapeutics Market by Application, 2023-2033, $ mn 105
Table 40. Italy mRNA Therapeutics Market by End User, 2023-2033, $ mn 105
Table 41. Russia mRNA Therapeutics Market by Product, 2023-2033, $ mn 107
Table 42. Russia mRNA Therapeutics Market by Application, 2023-2033, $ mn 107
Table 43. Russia mRNA Therapeutics Market by End User, 2023-2033, $ mn 107
Table 44. mRNA Therapeutics Market in Rest of Europe by Country, 2023-2033, $ mn 109
Table 45. APAC mRNA Therapeutics Market by Country, 2023-2033, $ mn 112
Table 46. Japan mRNA Therapeutics Market by Product, 2023-2033, $ mn 116
Table 47. Japan mRNA Therapeutics Market by Application, 2023-2033, $ mn 116
Table 48. Japan mRNA Therapeutics Market by End User, 2023-2033, $ mn 116
Table 49. China mRNA Therapeutics Market by Product, 2023-2033, $ mn 118
Table 50. China mRNA Therapeutics Market by Application, 2023-2033, $ mn 118
Table 51. China mRNA Therapeutics Market by End User, 2023-2033, $ mn 118
Table 52. Australia mRNA Therapeutics Market by Product, 2023-2033, $ mn 120
Table 53. Australia mRNA Therapeutics Market by Application, 2023-2033, $ mn 120
Table 54. Australia mRNA Therapeutics Market by End User, 2023-2033, $ mn 120
Table 55. India mRNA Therapeutics Market by Product, 2023-2033, $ mn 122
Table 56. India mRNA Therapeutics Market by Application, 2023-2033, $ mn 122
Table 57. India mRNA Therapeutics Market by End User, 2023-2033, $ mn 122
Table 58. South Korea mRNA Therapeutics Market by Product, 2023-2033, $ mn 124
Table 59. South Korea mRNA Therapeutics Market by Application, 2023-2033, $ mn 124
Table 60. South Korea mRNA Therapeutics Market by End User, 2023-2033, $ mn 124
Table 61. mRNA Therapeutics Market in Rest of APAC by Country/Region, 2023-2033, $ mn 126
Table 62. South America mRNA Therapeutics Market by Country, 2023-2033, $ mn 129
Table 63. Argentina mRNA Therapeutics Market by Product, 2023-2033, $ mn 132
Table 64. Argentina mRNA Therapeutics Market by Application, 2023-2033, $ mn 132
Table 65. Argentina mRNA Therapeutics Market by End User, 2023-2033, $ mn 132
Table 66. Brazil mRNA Therapeutics Market by Product, 2023-2033, $ mn 134
Table 67. Brazil mRNA Therapeutics Market by Application, 2023-2033, $ mn 134
Table 68. Brazil mRNA Therapeutics Market by End User, 2023-2033, $ mn 134
Table 69. Colombia mRNA Therapeutics Market by Product, 2023-2033, $ mn 136
Table 70. Colombia mRNA Therapeutics Market by Application, 2023-2033, $ mn 136
Table 71. Colombia mRNA Therapeutics Market by End User, 2023-2033, $ mn 136
Table 72. MEA mRNA Therapeutics Market by Country, 2023-2033, $ mn 140
Table 73. UAE mRNA Therapeutics Market by Product, 2023-2033, $ mn 143
Table 74. UAE mRNA Therapeutics Market by Application, 2023-2033, $ mn 143
Table 75. UAE mRNA Therapeutics Market by End User, 2023-2033, $ mn 143
Table 76. Saudi Arabia mRNA Therapeutics Market by Product, 2023-2033, $ mn 145
Table 77. Saudi Arabia mRNA Therapeutics Market by Application, 2023-2033, $ mn 145
Table 78. Saudi Arabia mRNA Therapeutics Market by End User, 2023-2033, $ mn 145
Table 79. Israel mRNA Therapeutics Market by Product, 2023-2033, $ mn 147
Table 80. Israel mRNA Therapeutics Market by Application, 2023-2033, $ mn 147
Table 81. Israel mRNA Therapeutics Market by End User, 2023-2033, $ mn 147
Table 82. Breakdown of World Market by Key Vendor, 2023, % 151
Table 83. Arcturus Therapeutics: Company Snapshot 154
Table 84. Arcturus Therapeutics: Business Segmentation 155
Table 85. Arcturus Therapeutics: Product Portfolio 155
Table 86. List of Risk Factors and Weight Percentages/Theoretical Maximum 169
Table 87. Definition of GMD Relative Risk Index Number (Relative RIN) and GMD Risk Intensity Level (RIL) 170
Table 88. Risk Evaluation for Investing in Global Market, 2023-2033 171
Table 89. Critical Success Factors and Key Takeaways 175