Table of Content


1. PREFACE
1.1. Scope of the Report
1.2. Research Methodology
1.3. Key Questions Answered
1.4. Chapter Outlines


2. EXECUTIVE SUMMARY


3. INTRODUCTION
3.1. Chapter Overview
3.2. Overview of Vascular Disrupting Agents
3.2.1. Mechanism of Action of Vascular Disrupting Agents
3.3 Types of Vascular Disrupting Agents
3.3.1. Small Molecule Vascular Disrupting Agents
3.3.1.1. Tubulin Binding Agents
3.3.1.2. Flavonoids
3.3.2. Ligand Directed Vascular Disrupting Agents
3.4. Benefits of Vascular Disrupting Agents
3.5. Challenges Associated with Vascular Disrupting Agents
3.6. Future Perspectives

4. VASCULAR DISRUPTING AGENTS MARKET LANDSCAPE
4.1. Chapter Overview
4.2. Vascular Disrupting Agents: Development Pipeline
4.2.1. Analysis by Phase of Development
4.2.2. Analysis by Therapeutic Area
4.2.3. Analysis by Target Disease Indication
4.2.4. Analysis by Phase of Development and Target Disease Indication
4.2.5. Analysis by Type of Molecule
4.2.6. Analysis by Target Disease Indication and Type of Molecule
4.2.7. Analysis by Type of Therapy
4.2.8. Analysis by Route of Administration
4.2.9. Analysis by Potential Combination Therapeutics
4.3. Vascular Disrupting Agents: Developer Landscape
4.3.1. Analysis by Year of Establishment
4.3.2. Analysis by Company Size
4.3.3. Analysis by Location of Headquarters
4.3.4. Leading Players: Analysis by Number of Drug Candidates

5. COMPANY PROFILES
5.1. Chapter Overview
5.2. AGC Biologics
5.2.1. Company Overview
5.2.2. Drug Portfolio: Vascular Disrupting Agents
5.2.2.1. Drug Profile: NGR-TNF
5.2.3. Recent Developments and Future Outlook
5.3. Avid Bioservices
5.3.1. Company Overview
5.3.2. Financial Information
5.3.3. Drug Portfolio: Vascular Disrupting Agents
5.3.3.1. Drug Profile: Bavituximab
5.3.4. Recent Developments and Future Outlook
5.4. Bionomics
5.4.1. Company Overview
5.4.2. Financial Information
5.4.3. Drug Portfolio: Vascular Disrupting Agents
5.4.3.1. Drug Profile: BNC105
5.4.4. Recent Developments and Future Outlook
5.5. Mateon Therapeutics
5.5.1. Company Overview
5.5.2. Drug Portfolio: Vascular Disrupting Agents
5.5.2.1. Drug Profile: CA4P
5.5.2.2. Drug Profile: OXi4503
5.5.3. Recent Developments and Future Outlook
5.6. Myrexis
5.6.1. Company Overview
5.6.2. Drug Portfolio: Vascular Disrupting Agents
5.6.2.1. Drug Profile: MPC-6827
5.6.3. Recent Developments and Future Outlook
5.7. VBL Therapeutics
5.7.1. Company Overview
5.7.2. Financial Information
5.7.3. Drug Portfolio: Vascular Disrupting Agents
5.7.3.1. Drug Profile: VB-111
5.7.4. Recent Developments and Future Outlook

6. CLINICAL TRIAL ANALYSIS
6.1. Chapter Overview
6.2. Scope and Methodology
6.3. Vascular Disrupting Agents: Clinical Trial Analysis
6.3.1. Analysis by Trial Registration Year
6.3.2. Analysis by Trial Registration Year and Trial Status
6.3.3. Analysis by Trial Registration Year and Number of Patients Enrolled
6.3.4. Analysis by Trial Phase
6.3.5. Analysis by Trial Phase and Number of Patients Enrolled
6.3.6. Geographical Analysis by Number of Clinical Trials
6.3.7. Geographical Analysis by Number of Patients Enrolled
6.3.8. Analysis by Study Design
6.3.9. Analysis by Trial Focus
6.3.10. Analysis by Drug Molecule
6.3.11. Analysis by Key Indications
6.3.12. Analysis by Type of Sponsor / Collaborator
6.3.13. Most Active Industry Players: Analysis by Number of Registered Trials
6.3.14. Most Active Non-Industry Players: Analysis by Number of Registered Trials

7. PUBLICATION ANALYSIS
7.1. Chapter Overview
7.2. Scope and Methodology
7.3. Vascular Disrupting Agents: List of Recent Publications
7.3.1. Analysis by Year of Publication
7.3.2. Emerging Focus Areas
7.3.3. Analysis by Popular Keywords
7.3.4. Analysis by Target Disease Indications
7.3.5. Analysis by Therapeutic Area
7.3.6. Popular Journals: Analysis by Number of Publications
7.3.7. Popular Journals: Analysis of Journal Impact Factor
7.3.8. Most Popular Authors: Analysis by Number of Publications

8. ACADEMIC GRANTS ANALYSIS
8.1. Chapter Overview
8.2. Scope and Methodology
8.3. Vascular Disrupting agents: Academic Grants Analysis
8.3.1. Analysis by Year of Grant Award
8.3.2. Analysis by Amount Awarded
8.3.3. Analysis by Administering Institute Center
8.3.4. Analysis by Support Period
8.3.5. Analysis by Administering Institute Center and Support Period
8.3.6. Analysis by Type of Grant Application
8.3.7. Analysis by Activity Code
8.3.8. Word Cloud Analysis: Emerging Focus Areas
8.3.9. Popular Recipient Organizations: Analysis by Number of Grants
8.3.10. Prominent Program Officers: Analysis by Number of Grants
8.3.11. Regional Distribution of Recipient Organizations

9. KOL ANALYSIS
9.1. Chapter Overview
9.2. Assumptions and Methodology
9.3. Principal Investigators of Vascular Disrupting Agents Focused Clinical Trials
9.3.1. Geographical Distribution of KOLs
9.3.2. Analysis by Type of Organization (KOL Affiliation)
9.3.3. Leading Organizations: Analysis by Number of Affiliated Principal Investigators
9.4. Prominent Key Opinion Leaders (KOLs)
9.5. KOL Benchmarking: Roots Analysis versus Third-Party Scoring (ResearchGate Score)
9.6. Profiles of Most Active KOLs
9.6.1. KOL Profile: KOL A
9.6.2. KOL Profile: KOL B
9.6.3. KOL Profile: KOL C
9.6.4. KOL Profile: KOL D
9.6.5. KOL Profile: KOL E
9.6.6. KOL Profile: KOL F

10. MARKET SIZING AND OPPORTUNITY ANALYSIS
10.1. Chapter Overview
10.2. Scope and Limitations
10.3. Key Assumptions and Forecast Methodology
10.4. Overall Vascular Disrupting Agents Market, 2021-2030
10.4.1. Vascular Disrupting Agents Market: Distribution by Target Indication
10.4.2. Vascular Disrupting Agents Market: Distribution by Therapeutic Area
10.4.3. Vascular Disrupting Agents Market: Distribution by Type of Molecule
10.4.4. Vascular Disrupting Agents Market: Distribution by Type of Therapy
10.4.5. Vascular Disrupting Agents Market: Distribution by Route of Administration
10.4.6. Vascular Disrupting Agents Market: Distribution by Geography
10.4.7. Product-wise Sales Forecast
10.4.7.1. Bavituximab (Avid Bioservices)
10.4.7.1.1. Target Patient Population
10.4.7.1.2. Sales Forecast (USD Million)
10.4.7.1.3. Net Present Value (USD Million)
10.4.7.1.4. Value Creation Analysis
10.4.7.2. Icaritin (Beijing Shenogen Biomedical)
10.4.7.2.1. Target Patient Population
10.4.7.2.2. Sales Forecast (USD Million)
10.4.7.2.3. Net Present Value (USD Million)
10.4.7.2.4. Value Creation Analysis
10.4.7.3. NGR-TNF (AGC Biologics)
10.4.7.3.1. Target Patient Population
10.4.7.3.2. Sales Forecast (USD Million)
10.4.7.3.3. Net Present Value (USD Million)
10.4.7.3.4. Value Creation Analysis
10.4.7.4. Padeliporfin (Steba biotech)
10.4.7.4.1. Target Patient Population
10.4.7.4.2. Sales Forecast (USD Million)
10.4.7.4.3. Net Present Value (USD Million)
10.4.7.4.4. Value Creation Analysis
10.4.7.5. Plinabulin (BeyondSpring Pharmaceuticals)
10.4.7.5.1. Target Patient Population
10.4.7.5.2. Sales Forecast (USD Million)
10.4.7.5.3. Net Present Value (USD Million)
10.4.7.5.4. Value Creation Analysis
10.4.7.6. VB-111 (VBL Therapeutics)
10.4.7.6.1. Target Patient Population
10.4.7.6.2. Sales Forecast (USD Million)
10.4.7.6.3. Net Present Value (USD Million)
10.4.7.6.4. Value Creation Analysis
11. CONCLUDING REMARKS
12. APPENDIX 1: TABULATED DATA
13. APPENDIX 2: LIST OF COMPANIES AND ORGANIZATIONS