Table of Content
1. PREFACE
1.1. Scope of the Report
1.2. Research Methodology
1.3. Key Questions Answered
1.4. Chapter Outlines
2. EXECUTIVE SUMMARY
3. INTRODUCTION
3.1. Overview of Regulatory T-Cell Therapies
3.2. Characteristics of Treg Cell Therapies
3.3. Function of Treg Cell Therapies
3.4 Mechanism of Action of Treg Cell Therapies
3.5 Advantages of Treg Cell Therapies
3.6 Challenges and Future Perspectives Associated with Treg Cell Therapies
4. MARKET LANDSCAPE
4.1. Treg Cell Therapies: Overall Market Landscape
4.1.1. Analysis by Type of Product
4.1.2. Analysis by Phase of Development
4.1.3. Analysis by Therapeutic Area
4.1.4. Analysis by Phase of Development and Therapeutic Area
4.1.5. Analysis by Target Indication
4.1.6. Analysis by Source of T-Cells
4.1.7. Analysis by Route of Administration
4.1.8. Analysis by Dose Frequency
4.1.9. Analysis by Target Patient Segment
4.1.10. Analysis by Type of Therapy
4.1.11. Analysis by Type of Developer
4.1.12. Leading Industry Players: Analysis by Number of Treg Cell Therapies
4.1.13. Leading Non-Industry Players: Analysis by Number of Treg Cell Therapies
4.2. Treg Cell Therapies: List of Developers
4.2.1. Analysis by Year of Establishment
4.2.2. Analysis by Company Size
4.2.3. Analysis by Location of Headquarters
4.2.4. Regional Landscape of Developers
5. THERAPY PROFILES
5.1. arTreg-CSB (National Institute of Allergy and Infectious Diseases / Immune Tolerance Network)
5.1.1. Company Overview
5.1.2. Therapy Overview
5.1.3. Clinical Trial Information
5.1.4. Clinical Trial Endpoints
5.1.5. Dosage Regimen
5.2. CLBS03 (Caladrius Biosciences)
5.2.1. Company Overview
5.2.2. Therapy Overview
5.2.3. Clinical Trial Information
5.2.4. Clinical Trial Endpoints
5.2.5. Dosage Regimen
5.2.6. Key Insights
5.2.7. Estimated Sales Revenue
5.3. ILT-101 (Iltoo Pharma / Assistance Publique - H?pitaux de Paris)
5.3.1. Company Overview
5.3.2. Therapy Overview
5.3.3. Clinical Trial Information
5.3.4. Clinical Trial Endpoints
5.3.5. Dosage Regimen
5.3.6. Estimated Sales Revenue
5.4. Low Dose IL-2 (Iltoo Pharma / Assistance Publique - H?pitaux de Paris)
5.4.1. Company Overview
5.4.2. Therapy Overview
5.4.3. Clinical Trial Information
5.4.4. Clinical Trial Endpoints
5.4.5. Dosage Regimen
5.4.6. Key Insights
5.5. NKTR-358 / LY3471851(Nektar Therapeutics / Eli Lilly)
5.5.1. Company Overview
5.5.2. Therapy Overview
5.5.3. Clinical Trial Information
5.5.4. Clinical Trial Endpoints
5.5.5. Dosage Regimen
5.5.6 Key Insights
5.5.7. Estimated Sales Revenue
5.6. RGI-2001 (REGiMMUNE)
5.6.1. Company Overview
5.6.2. Therapy Overview
5.6.3. Clinical Trial Information
5.6.4. Clinical Trial Endpoints
5.6.5. Dosage Regimen
5.6.6. Key Insights
5.6.7. Estimated Sales Revenue
5.7. rhIL-2 (Iltoo Pharma / Assistance Publique - H?pitaux de Paris)
5.7.1. Company Overview
5.7.2. Therapy Overview
5.7.3. Clinical Trial Information
5.7.4. Clinical Trial Endpoints
5.7.5. Dosage Regimen
5.7.6. Estimated Sales Revenue
5.8. TR004 (Miltenyi Biotec)
5.8.1. Company Overview
5.8.2. Therapy Overview
5.8.3. Clinical Trial Information
5.8.4. Clinical Trial Endpoints
5.8.5. Dosage Regimen
5.8.6. Estimated Sales Revenue
5.9. TX200 (Sangamo Therapeutics)
5.9.1 Company Overview
5.9.2. Therapy Overview
5.9.3. Clinical Trial Information
5.9.4. Clinical Trial Endpoints
5.9.5. Dosage Regimen
5.9.6. Key Insights
5.10. VT301 / GB301 (VT Bio / BHT Lifescience Austrailia)
5.10.1. Company Overview
5.10.2. Therapy Overview
5.10.3. Clinical Trial Information
5.10.4. Clinical Trial Endpoints
5.10.5. Dosage Regimen
6. CLINICAL TRIAL ANALYSIS
6.1. Methodology and Parameters
6.2. Treg Cell Therapies: Snapshot of Clinical Trials (till July 2021)
6.2.1. Analysis by Trial Registration Year and Enrolled Patient Population
6.2.2. Analysis by Trial Phase
6.2.3. Analysis by Trial Phase and Enrolled Patient Population
6.2.4. Analysis by Trial Recruitment Status
6.2.5. Analysis by Year and Trial Recruitment Status
6.2.6. Analysis by Type of Allocation
6.2.7. Analysis by Purpose of Study
6.2.8. Analysis by Type of Masking
6.2.9 Analysis by Intervention Model
6.2.10. Analysis by Year and Trial Phase
6.2.11. Analysis by Year, Average Time Taken and Trial Phase
6.2.12. Analysis by Target Patient Segment
6.2.13. Analysis by Gender of Enrolled Patients
6.2.14. Analysis by Type of Sponsor(s)
6.2.15. Leading Non-Industry Players: Analysis by Number of Trials Registered
6.2.16. Leading Industry Players: Analysis by Number of Trials Registered
6.2.17. Analysis by Location of Trial
6.2.18. Analysis by Trial Status and Geography
7. PARTNERSHIPS AND COLLABORATIONS
7.1. Chapter Overview
7.2. Treg Cell Therapies: Partnerships and Collaborations
7.2.1 Analysis by Year of Partnership
7.2.2. Analysis by Type of Partnership
7.2.3. Analysis by Year and Type of Partnership
7.2.4. Analysis by Type of Product
7.2.5. Analysis by Year and Type of Product
7.2.6. Analysis by Therapeutic Area
7.2.7. Analysis by Type of Partner
7.2.8. Analysis by Type of Partner and Type of Partnership
7.2.9. Leading Industry Players: Analysis by Number of Partnerships
7.2.10. Region-wise Distribution
7.2.11. Country-wise Distribution
8. FUNDING AND INVESTMENT ANALYSIS
8.1. Chapter Overview
8.2. Treg Cell Therapies: Funding and Investment
8.2.1. Analysis by Year of Investment and Amount Invested
8.2.2. Analysis by Type of Funding
8.2.3. Analysis by Year of Investment and Type of Funding
8.2.4. Analysis by Type of Product
8.2.5. Analysis by Year of Investment and Type of Product
8.2.6. Analysis by Type of Investor
8.2.7. Leading Investors: Analysis by Number of Funding Instances
8.2.8. Leading Players: Analysis by Number of Funding Instances
8.2.9. Analysis by Geography
9. PORTER’S FIVE FORCES ANALYSIS
9.1. Chapter Overview
9.2. Methodology and Key Parameters
9.3 Porter’s Five Forces
9.3.1. Threat of New Entrants
9.3.2. Bargaining Power of Developers
9.3.3. Bargaining Power of Customers
9.3.4. Threat of Available Substitute Therapies
9.3.5. Rivalry Among Existing Competitors
10. COMPANY PROFILES
10.1. Abata Therapeutics
10.1.1. Company Overview
10.1.2. Key Insights
10.1.3. Product Portfolio
10.1.4 Recent Developments and Future Outlook
10.2. Cellenkos
10.2.1. Company Overview
10.2.2. Key Insights
10.2.3. Product Portfolio
10.2.4 Recent Developments and Future Outlook
10.3. Coya Therapeutics
10.3.1. Company Overview
10.3.2. Key Insights
10.3.3. Product Portfolio
10.3.4 Recent Developments and Future Outlook
10.4. ILTOO Pharma
10.4.1. Company Overview
10.4.2. Key Insights
10.4.3. Product Portfolio
10.4.4 Recent Developments and Future Outlook
10.5. NEKTAR
10.5.1. Company Overview
10.5.2. Key Insights
10.5.3. Product Portfolio
10.5.4 Recent Developments and Future Outlook
10.6. Roche
10.6.1. Company Overview
10.6.2. Key Insights
10.6.3. Financial Information
10.6.4 Product Portfolio
10.6.5 Recent Developments and Future Outlook
10.7. Sonoma Biotherapeutics
10.7.1. Company Overview
10.7.2. Key Insights
10.7.3. Product Portfolio
10.7.4 Recent Developments and Future Outlook
10.8. TeraImmune
10.8.1. Company Overview
10.8.2. Key Insights
10.8.3. Product Portfolio
10.8.4 Recent Developments and Future Outlook
10.9. TRACT Therapeutics
10.9.1. Company Overview
10.9.2. Key Insights
10.9.3. Product Portfolio
10.9.4 Recent Developments and Future Outlook
11. MARKET SIZING AND OPPORTUNITY ANALYSIS
11.1. Forecast Methodology and Key Assumptions
11.2. Global Treg Cell Therapies Market, 2021-2030
11.2.1. Treg Cell Therapies Market: Analysis by Type of Product
11.2.2. Treg Cell Therapies Market: Analysis by Target Indication
11.2.3. Treg Cell Therapies Market: Analysis by Key Players
11.2.4. Treg Cell Therapies Market: Analysis by Geography
11.2.5. Treg Cell Therapies: Forecast of Individual Product Sales
11.2.5.1. CLBS03 (Caladrius Biosciences): Estimated Sales Revenues
11.2.5.2. ILT-101 (Iltoo Pharma / Assistance Publique - H?pitaux de Paris): Estimated Sales Revenues
11.2.5.3. NKTR-358 / LY3471851(Nektar Therapeutics / Eli Lilly): Estimated Sales Revenues
11.2.5.4. RGI-2001 (REGiMMUNE): Estimated Sales Revenues
11.2.5.5. rhIL-2 (Iltoo Pharma / Assistance Publique - H?pitaux de Paris): Estimated Sales Revenues
11.2.5.6. TR004 (Miltenyi Biotec): Estimated Sales Revenues
11.2.5.7. VT301 / GB301 (VT Bio / BHT Lifescience Austrailia): Estimated Sales Revenues
12. CONCLUSION
13. EXECUTIVE INSIGHTS
13.1. Chapter Overview
13.2. Oncurious
13.2.1. Company Snapshot
13.2.2. Interview Transcript: Pascal Merchiers, Chief Scientific Officer
14. APPENDICES
14.1 Miscellaneous Charts and Figures
14.2 List of Figures
14.3 List of Tables
14.4 List of Companies and Organizations