Table of Content


1. Introduction To Spleen Tyrosine Kinase (Syk)
1.1 Overview of Syk Protein
1.2 Structure of Syk Protein
1.3 Potential Of Syk As Drug Target


2. Syk Inhibitors – Mechanism Of Action


3. Role Of Syk Inhibitors By Indication
3.1 Cancer
3.2 Autoimmune diseases
3.3 Viral Infections
3.4 Cardiovascular Diseases


4. Fostamatinib (Tavalisse) - 1st Approved Syk Inhibitor
4.1 Overview & Patent Analysis
4.2 Pricing & Dosage Analysis
4.3 Sales Analysis (2018 – 2022)


5. Global Syk Inhibitors Market Analysis
5.1 Current Market Scenario
5.2 Syk Inhibitors Market Future Outlook (2023 -2028)


6. Global Syk Inhibitors Clinical Pipeline Overview
6.1 By Country
6.2 By Indication
6.3 By Organization
6.4 By Phase



7. Global Syk Inhibitors Clinical Pipeline By Company, Indication & Phase
7.1 Research
7.2 Preclinical
7.3 Phase-I
7.4 Phase-I/II
7.5 Phase-II
7.6 Phase-III


8. Marketed Syk Inhibitors Clinical & Patent Insight


9. Global Syk Inhibitors Market Dynamics
9.1 Market Drivers
9.2 Market Restraints


10. Competitive Landscape
10.1 Calithera Biosciences
10.2 CrystalGenomics
10.3 CSPC Ouyi Pharmaceutical
10.4 Genosco
10.5 Hanmi Pharmaceutical
10.6 HUTCHMED
10.7 IACTA Pharmaceuticals
10.8 Kronos Bio
10.9 Libertas Bio
10.10 Oscotec
10.11 Rigel Pharmaceuticals
10.12 Takeda Oncology



List of Figures


Figure 1-1: Syk – History & Discovery
Figure 1-2: Syk – Structure Of Protein

Figure 4-1: Fostamatinib – Approval Year By Country/Region
Figure 4-2: Fostamatinib – Patents Overview
Figure 4-3: US - Price for 60 tablets & Price Per Unit of 100 mg and 150 mg Fostamatinib Doses (US$), February’2023
Figure 4-4: EU - Price for 60 tablets & Price Per Unit of 100 mg Fostamatinib Dose (US$), February’2023
Figure 4-5: EU - Price for 60 tablets & Price Per Unit of 150 mg Fostamatinib Dose (US$), February’2023
Figure 4-6: Tavalisse - Initial & Increased Dose for the Treatment of Chronic Immune Thrombocytopenia (mg)
Figure 4-7: Global - Fostamatinib Sales (US$ Million), 2018-2022
Figure 4-8: Global - Fostamatinib Quarterly Sales (US$ Million), 2022
Figure 4-9: Fostamatinib – Cost of Product Sales (US$ ?000), 2018-2022*
Figure 4-10: Fostamatinib – Cost of Product Sales (US$ ?000), Q1-Q3’2022
Figure 4-11: Global – Total Fostamatinib Bottles Shipped, 2020-2022
Figure 4-12: Global – Total Fostamatinib Bottles Shipped, 2022

Figure 5-1: Global – Syk Inhibitor Drug Market (US$ Million), 2018-2022
Figure 5-2: Global - Syk Inhibitor Drug Market (US$ Million), Q1 – Q4’2022
Figure 5-3: Global – Syk Inhibitor Drug Market (US$ Million), 2023-2028

Figure 6-1: Global – Number Of Syk Inhibitors Clinical Trials By Country, 2023 Till 2028
Figure 6-2: Global – Number Of Syk Inhibitors Clinical Trials By Indication, 2023 Till 2028
Figure 6-3: Global – Number Of Syk Inhibitors Clinical Trials By Organization, 2023 Till 2028
Figure 6-4: Global – Number Of Syk Inhibitors Clinical Trials By Phase, 2023 Till 2028

Figure 9-1: Syk Inhibitors Market Drivers
Figure 9-2: Syk Inhibitors Market Challenges