Table of Content

1 Market
1.1 Product Definition
1.1.1 Radiographic Axial Spondyloarthritis
1.1.2 Non-radiographic Axial Spondyloarthritis (nr-axSpA):
1.1.3 Inclusion and Exclusion
1.2 Market Scope
1.2.1 Key Questions Answered in the Report
1.3 Research Methodology
1.3.1 Global Axial Spondyloarthritis Market: Research Methodology
1.3.2 Data Sources
1.3.2.1 Primary Data Sources
1.3.2.2 Secondary Data Sources
1.3.3 Market Estimation Model
1.3.4 Criteria for Company Profiling
1.4 Market Overview
1.4.1 Introduction
1.4.2 Current Market Size and Growth Potential, $Million, 2021-2032
1.4.3 Disease Background
1.4.4 Treatment Plan
1.4.4.1 Tumor Necrosis Factor (TNF) Inhibitors
1.4.4.2 Interleukin (IL)-17 Inhibitors
1.4.4.3 Janus Kinase (JAK) Inhibitors
1.4.5 Treatment Guidelines for Axial Spondyloarthritis
1.4.5.1 American College of Rheumatology (ACR) Recommendations
1.4.5.2 Assessment of SpondyloArthritis international Society (ASAS) and European League Against Rheumatism (EULAR) Recommendations
1.4.6 Epidemiology of Axial Spondyloarthritis
1.4.6.1 U.S. Epidemiology of Axial Spondyloarthritis
1.4.6.2 Epidemiology of Axial Spondyloarthritis (Germany, France, Italy, and Spain (EU4) + U.K.)
1.4.6.3 Japan Epidemiology of Axial Spondyloarthritis
1.4.7 Pipeline Analysis
1.4.7.1 By Clinical Phase
1.4.8 Impact of COVID-19 on Global Axial Spondyloarthritis Market
1.4.8.1 Interruption in Research and Clinical Development and Commercial Operation
1.4.8.1.1 Research and Clinical Development
1.4.8.1.2 Commercial Operation and Access
1.4.8.2 Navigating Crisis Recovery and Looking to the Future

2 Industry Analysis
2.1 Overview
2.2 Legal Requirements and Frameworks in the U.S.
2.2.1 Clinical Trial Authorization
2.2.2 Marketing Authorization
2.2.3 U.S. Food and Drug Administration Guidelines for Biologics License Application (BLA)
2.2.4 Post-Authorization Regulations
2.3 Legal Requirements and Frameworks in Europe
2.4 Legal Requirements and Frameworks in Japan
2.5 Reimbursement and Cost Analysis
2.5.1 U.S.
2.5.2 Europe

3 Market Dynamics
3.1 Overview
3.2 Impact Analysis
3.3 Market Drivers
3.3.1 The Introduction of Novel Products
3.3.2 Increasing Awareness About the Disease
3.3.3 Rising Research and Development Investments
3.4 Market Restraints
3.4.1 High Treatment Cost Impacting the Adoption Rate
3.4.2 Increased Delay in Diagnosis
3.5 Market Opportunities
3.5.1 Massive Scope in Emerging Markets

4 Competitive Landscape
4.1 Overview
4.2 Key Developments and Strategies
4.2.1 Regulatory and Legal Activities
4.2.2 Product Approvals
4.2.3 Partnerships and Alliances
4.2.4 Merger and Acquisition Activities
4.3 Market Share Analysis, by Company (2021)
4.4 Growth Share Analysis

5 Global Axial Spondyloarthritis Market (by Commercialized Therapies), $Million, 2021-2032
5.1 Overview
5.2 Anti-Tumor Necrosis Factor (TNF) Therapy
5.2.1 Cimzia (Certolizumab?Pegol)
5.2.1.1 Cimzia for Indication 1 (Ankylosing Spondylitis)
5.2.1.2 Cimzia for Indication 2 (Non-radiographic Axial Spondyloarthritis)
5.2.2 Simponi (Golimumab)
5.2.2.1 Simponi for Indication 1 (Ankylosing Spondylitis)
5.2.2.1.1 Simponi as Subcutaneous Formulation
5.2.2.1.2 Simponi AREA as an Intravenous Formulation
5.2.2.2 Simponi for Indication 2 (Non-radiographic Axial Spondyloarthritis)
5.3 Anti-Interleukin (IL) Therapy
5.3.1 Cosentyx (Secukinumab)
5.3.1.1 Cosentyx for Indication 1 (Ankylosing Spondylitis)
5.3.1.2 Cosentyx for Indication 2 (Non-radiographic Axial Spondyloarthritis)
5.3.2 Taltz (Ixekizumab)
5.3.2.1 Taltz for Indication 1 (Ankylosing Spondylitis)
5.3.2.2 Taltz for Indication 2 (Non-radiographic Axial Spondyloarthritis)
5.3.3 Lumicef (Brodalumab/KHK4827)
5.3.3.1 Lumicef for Indication 1 (Ankylosing Spondylitis)
5.3.3.2 Lumicef for Indication 2 (Non-radiographic Axial Spondyloarthritis)
5.4 Anti-Janus Kinase (JAK) Therapy
5.4.1 Xeljanz/Xeljanz XR (Tofacitinib)

6 Global Axial Spondyloarthritis Market (by Potential Pipeline Products), $Million, 2021-2032
6.1 Overview
6.2 Anti-Janus Kinase (JAK) Therapy
6.2.1 Rinvoq (Upadacitinib)
6.2.2 SHR0302
6.3 Anti-Interleukin (IL)-17 Therapy
6.3.1 Bimzelx (Bimekizumab)
6.3.1.1 Bimzelx for Indication 1 (Ankylosing Spondylitis)
6.3.1.2 Bimzelx for Indication 2 (Non-radiographic Axial Spondyloarthritis)
6.4 Other Therapy
6.4.1 IZN-101 (Namilumab)
6.4.2 Otezla (Apremilast)

7 Global Axial Spondyloarthritis Market (by Indication), $Million, 2021-2032
7.1 Overview
7.1.1 Ankylosing Spondylitis
7.1.2 Non-radiographic Axial Spondyloarthritis

8 Global Axial Spondyloarthritis Market (by Country), $Million, 2021-2032
8.1 Overview
8.1.1 Commercialized Products in the U.S.
8.1.2 Commercialized Products in EU4 + U.K.
8.1.3 Commercialized Products in Japan
8.2 U.S.
8.3 Germany
8.4 France
8.5 U.K.
8.6 Italy
8.7 Spain
8.8 Japan

9 Company Profiles
9.1 Overview
9.2 AbbVie Inc.
9.2.1 Company Overview
9.2.2 Role of AbbVie Inc. in the Global Axial Spondyloarthritis Market
9.2.3 Financials
9.2.4 Key Insights About Financial Health of the Company
9.2.5 SWOT Analysis
9.3 Amgen Inc.
9.3.1 Company Overview
9.3.2 Role of Amgen Inc. in the Global Axial Spondyloarthritis Market
9.3.3 Financials
9.3.4 Key Insights About Financial Health of the Company
9.3.5 SWOT Analysis
9.4 Bristol-Myers Squibb Company
9.4.1 Company Overview
9.4.2 Role of Bristol-Myers Squibb Company in the Global Axial Spondyloarthritis Market
9.4.3 Financials
9.4.4 Key Insights About Financial Health of the Company
9.4.5 SWOT Analysis
9.5 Eli Lilly and Company
9.5.1 Company Overview
9.5.2 Role of Eli Lilly and Company in the Global Axial Spondyloarthritis Market
9.5.3 Financials
9.5.4 Key Insights About Financial Health of the Company
9.5.5 SWOT Analysis
9.6 FunPep Co., Ltd.,
9.6.1 Company Overview
9.6.2 Role of FunPep Co., Ltd., in the Global Axial Spondyloarthritis Market
9.6.3 SWOT Analysis
9.7 Johnson & Johnson Services, Inc.
9.7.1 Company Overview
9.7.2 Role of Johnson & Johnson Services, Inc. in the Global Axial Spondyloarthritis Market
9.7.3 Financials
9.7.4 Key Insights About Financial Health of the Company
9.7.5 SWOT Analysis
9.8 Kyowa Kirin Co., Ltd.
9.8.1 Company Overview
9.8.2 Role of Kyowa Kirin Co., Ltd. in the Global Axial Spondyloarthritis Market
9.8.3 Financials
9.8.4 Key Insights About Financial Health of the Company
9.8.5 SWOT Analysis
9.9 Merck & Co., Inc.
9.9.1 Company Overview
9.9.2 Role of Merck & Co., Inc. in the Global Axial Spondyloarthritis Market
9.9.3 Financials
9.9.4 Key Insights About Financial Health of the Company
9.9.5 SWOT Analysis
9.1 Novartis International AG
9.10.1 Company Overview
9.10.2 Role of Novartis International AG in the Global Axial Spondyloarthritis Market
9.10.3 Financials
9.10.4 Key Insights About Financial Health of the Company
9.10.5 SWOT Analysis
9.11 Pfizer Inc.
9.11.1 Company Overview
9.11.2 Role of Pfizer Inc. in the Global Axial Spondyloarthritis Market
9.11.3 Financials
9.11.4 Key Insights About Financial Health of the Company
9.11.5 SWOT Analysis
9.12 Takeda Pharmaceutical Company Limited
9.12.1 Company Overview
9.12.2 Role of Takeda Pharmaceutical Company Limited in the Global Axial Spondyloarthritis Market
9.12.3 Financials
9.12.4 Key Insights About Financial Health of the Company
9.12.5 SWOT Analysis
9.13 UCB S.A.
9.13.1 Company Overview
9.13.2 Role of UCB S.A. in the Global Axial Spondyloarthritis Market
9.13.3 Financials
9.13.4 Key Insights About Financial Health of the Company
9.13.5 SWOT Analysis
List of Figures
Figure 1: Axial Spondyloarthritis Drugs Approved by U.S. FDA (2015-2021)
Figure 2: Axial Spondyloarthritis Drugs Global Clinical Trials (by Phase)
Figure 3: Global Axial Spondyloarthritis Market (by Commercialized Therapies), $Million, 2021-2032
Figure 4: Global Axial Spondyloarthritis Market: Impact Analysis
Figure 5: Global Axial Spondyloarthritis Market (by Potential Pipeline Products), $Million, 2021-2032
Figure 6: Global Axial Spondyloarthritis Market (by Indication), $Million, 2021-2032
Figure 7: Global Axial Spondyloarthritis Market (by Country), $Million, 2021-2032
Figure 8: Global Axial Spondyloarthritis Market: Segmentation
Figure 9: Global Axial Spondyloarthritis Market: Methodology
Figure 10: Primary Research Methodology
Figure 11: Bottom-Up Approach (Segment-Wise Analysis)
Figure 12: Step by Step Approach
Figure 13: Global Axial Spondyloarthritis Market, $Million, 2021-2032
Figure 14: Evolution of Axial Spondyloarthritis (axSpA)
Figure 15: Treatment Plan for Axial Spondyloarthritis
Figure 16: Complications with Tumor Necrosis Factor (TNF) Inhibitors
Figure 17: Complications with Interleukin (IL)-17 Inhibitors
Figure 18: Complications with Janus Kinase (JAK) Inhibitors
Figure 19: Treatment Guidelines for Axial Spondyloarthritis, U.S.
Figure 20: Assessment of Spondyloarthritis International Society (ASAS) and The European League Against Rheumatism (EULAR) Recommendations for the Management of Axial Spondyloarthritis (axSpA)
Figure 21: Assessment of Spondyloarthritis International Society (ASAS) and The European League Against Rheumatism (EULAR) 13 Recommendations
Figure 22: Types of Axial Spondyloarthritis
Figure 23: Axial Spondyloarthritis Prevalence (U.S. + EU4 + U.K. + Japan), 2020-2032
Figure 24: Axial Spondyloarthritis Prevalence in the U.S., 2020-2032
Figure 25: Percentage of Axial Spondyloarthritis Prevalence (by Country), 2020
Figure 26: Axial Spondyloarthritis Prevalence in the EU4 + U.K., 2020-2032
Figure 27: Axial Spondyloarthritis Prevalence in Japan, 2020-2032
Figure 28: Axial Spondyloarthritis Emerging Therapies: Developmental Phases
Figure 29: Key Steps to Navigate Crisis Recovery
Figure 30: Clinical Trial Authorization for Axial Spondyloarthritis Therapeutics
Figure 31: Process for Obtaining Marketing Authorization
Figure 32: U.S. Food and Drug Administration Review Timeline
Figure 33: EMA Review Timeline
Figure 34: Current Reimbursement Scenario in Europe
Figure 35: Number of Clinical Trials for Axial Spondyloarthritis (by Major Players)
Figure 36: Factors Responsible for Delayed Diagnosis in Axial Spondyloarthritis
Figure 37: Share of Key Developments and Strategies, January 2019-February 2022
Figure 38: Regulatory and Legal Activities (by Company), January 2019 to February
Figure 39: Product Approvals (by Company), January 2019 and February 2022
Figure 40: Partnerships and Alliances (by Company), January 2019 and February 2022
Figure 41: Merger and Acquisition Activities (by Company), January 2019 and February 2022
Figure 42: Market Share Analysis (by Company), 2021
Figure 43: Growth Share Matrix for Global Axial Spondyloarthritis Market (by Company), 2021
Figure 44: Global Axial Spondyloarthritis Market (by Commercialized Therapies), $Million, 2021-2032
Figure 45: Global Axial Spondyloarthritis Market (by Anti-Tumor Necrosis Factor (TNF) Therapy), $Million, 2021-2032
Figure 46: Global Revenue for Cimzia, $Million, 2021-2032
Figure 47: Global Revenue for Cimzia (Ankylosing Spondylitis), $Million, 2021-2032
Figure 48: Global Revenue for Cimzia (Non-radiographic Axial Spondyloarthritis), $Million, 2021-2032
Figure 49: Global Revenue for Simponi, $Million, 2021-2032
Figure 50: Global Revenue for Simponi (Ankylosing Spondylitis), $Million, 2021-2032
Figure 51: Global Revenue for Simponi AREA (Ankylosing Spondylitis), $Million, 2021-2032
Figure 52: Global Revenue for Simponi (Non-radiographic Axial Spondyloarthritis), $Million, 2021-2032
Figure 53: Global Axial Spondyloarthritis Market (by Anti-Interleukin (IL) Therapy), $Million, 2021-2032
Figure 54: Global Revenue for Cosentyx, $Million, 2021-2032
Figure 55: Global Revenue for Cosentyx (Ankylosing Spondylitis), $Million, 2021-2032
Figure 56: Global Revenue for Cosentyx (Non-radiographic Axial Spondyloarthritis), $Million, 2021-2032
Figure 57: Global Revenue for Taltz, $Million, 2021-2032
Figure 58: Global Revenue for Taltz (Ankylosing Spondylitis), $Million, 2021-2032
Figure 59: Global Revenue for Taltz (Non-radiographic Axial Spondyloarthritis), $Million, 2021-2032
Figure 60: Global Revenue for Lumicef, $Million, 2021-2032
Figure 61: Global Revenue for Lumicef (Ankylosing Spondylitis), $Million, 2021-2032
Figure 62: Global Revenue for Lumicef (Non-radiographic Axial Spondyloarthritis), $Million, 2021-2032
Figure 63: Global Revenue for Xeljanz/Xeljanz XR, $Million, 2021-2032
Figure 64: Global Axial Spondyloarthritis Market (by Potential Pipeline Products), $Million, 2021-2032
Figure 65: Global Axial Spondyloarthritis Market (by Potential Pipeline Products), by Anti-Janus Kinase Therapy), $Million, 2021-2032
Figure 66: Global Revenue for Rinvoq, $Million, 2021-2032
Figure 67: Upadaticinib Phase III Clinical Trial Design for Non-radiographic Axial Spondyloarthritis
Figure 68: Global Revenue for SHR0302, $Million, 2021-2032
Figure 69: SHR0302 Phase II/ Phase III Clinical Trial Design for Ankylosing Spondylitis
Figure 70: Global Revenue for Bimzelx, $Million, 2021-2032
Figure 71: Global Revenue for Bimzelx (Ankylosing Spondylitis), $Million, 2021-2032
Figure 72: Bimzelx Phase III Clinical Trial Design for Ankylosing Spondylitis
Figure 73: Global Revenue for Bimzelx (Non-radiographic Axial Spondyloarthritis), $Million, 2021-2032
Figure 74: Bimzelx Phase III Clinical Trial Design for Non-radiographic Axial Spondyloarthritis
Figure 75: Global Axial Spondyloarthritis Market (by Potential Pipeline Products), by Other Therapy), $Million, 2021-2032
Figure 76: Global Revenue for IZN-101, $Million, 2021-2032
Figure 77: IZN-101 Phase II Clinical Trial Design for Axial Spondyloarthritis
Figure 78: Global Revenue for Otezla, $Million, 2021-2032
Figure 79: Otezla Phase III Clinical Trial Design for Ankylosing Spondylitis
Figure 80: Global Axial Spondyloarthritis Market (by Indication), $Million, 2021-2032
Figure 81: Global Axial Spondyloarthritis Market (by Indication, by Ankylosing Spondylitis), $Million, 2021-2032
Figure 82: Global Axial Spondyloarthritis Market (by Indication, by Non-Radiographic Axial Spondyloarthritis), $Million, 2021-2032
Figure 83: Global Axial Spondyloarthritis Market (by Country), $Million, 2021-2032
Figure 84: U.S. Axial Spondyloarthritis Market, $Million, 2021-2032
Figure 85: Germany Axial Spondyloarthritis Market, $Million, 2021-2032
Figure 86: France Axial Spondyloarthritis Market, $Million, 2021-2032
Figure 87: U.K. Axial Spondyloarthritis Market, $Million, 2021-2032
Figure 88: Italy Axial Spondyloarthritis Market, $Million, 2021-2032
Figure 89: Spain Axial Spondyloarthritis Market, $Million, 2021-2032
Figure 90: Japan Axial Spondyloarthritis Market, $Million, 2021-2032
Figure 91: Total Number of Companies Profiled
Figure 92: AbbVie Inc.: Pre-Clinical and Clinical Assets
Figure 93: AbbVie Inc.: Overall Financials, $Million, 2019-2021
Figure 94: AbbVie, Inc.: Revenue (by Region), $Million, 2019-2021
Figure 95: AbbVie Inc.: R&D Expenditure, $Million, 2019-2021
Figure 96: AbbVie Inc.: SWOT Analysis
Figure 97: Amgen Inc.: Pre-Clinical and Clinical Assets
Figure 98: Amgen Inc.: Overall Financials, $Million, 2019-2021
Figure 99: Amgen Inc.: Revenue (by Region), $Million, 2019-2021
Figure 100: Amgen Inc.: R&D Expenditure, $Million, 2019-2021
Figure 101: Amgen Inc.: SWOT Analysis
Figure 102: Bristol-Myers Squibb Company: Pre-Clinical and Clinical Assets
Figure 103: Bristol-Myers Squibb Company: Overall Financials, $Million, 2019-2021
Figure 104: Bristol-Myers Squibb Company: Revenue (by Region), $Million, 2019-2021
Figure 105: Bristol-Myers Squibb Company: R&D Expenditure, $Million, 2019-2021
Figure 106: Bristol-Myers Squibb Company: SWOT Analysis
Figure 107: Eli Lilly and Company: Commercialized Therapy
Figure 108: Eli Lilly and Company: Overall Financials, $Million, 2019-2021
Figure 109: Eli Lilly and Company: Revenue (by Region), $Million, 2019-2021
Figure 110: Eli Lilly and Company: R&D Expenditure, $Million, 2019-2021
Figure 111: Eli Lilly and Company: SWOT Analysis
Figure 112: FunPep Co., Ltd.: Pre-Clinical and Clinical Assets
Figure 113: FunPep Co., Ltd.: SWOT Analysis
Figure 114: Johnson & Johnson Services, Inc.: Commercialized Therapy
Figure 115: Johnson & Johnson Services, Inc.: Overall Financials, $Million, 2019-2021
Figure 116: Johnson & Johnson Services, Inc.: Revenue (by Segment), $Million, 2019-2021
Figure 117: Johnson & Johnson Services, Inc.: Revenue (by Region), $Million, 2019-2021
Figure 118: Johnson & Johnson Services, Inc.: R&D Expenditure, $Million, 2019-2021
Figure 119: Johnson & Johnson Services, Inc.: SWOT Analysis
Figure 120: Kyowa Kirin Co., Ltd. Commercialized Therapy
Figure 121: Kyowa Kirin Co., Ltd. Overall Financials, $Million, 2019-2021
Figure 122: Kyowa Kirin Co., Ltd. Revenue (by Region), $Million, 2019-2021
Figure 123: Kyowa Kirin Co., Ltd. R&D Expenditure, $Million, 2019-2021
Figure 124: Kyowa Kirin Co., Ltd. SWOT Analysis
Figure 125: Merck & Co., Inc.: Commercialized Therapy
Figure 126: Merck & Co., Inc.: Overall Financials, $Million, 2019-2021
Figure 127: Merck & Co., Inc.: Revenue (by Segment), $Million, 2019-2021
Figure 128: Merck & Co., Inc.: Revenue (by Region), $Million, 2019-2021
Figure 129: Merck & Co., Inc.: R&D Expenditure, $Million, 2019-2021
Figure 130: Merck & Co., Inc.: SWOT Analysis
Figure 131: Novartis International AG: Commercialized Therapy
Figure 132: Novartis International AG: Overall Financials, $Million, 2019-2021
Figure 133: Novartis International AG: Revenue (by Segment), $Million, 2019-2021
Figure 134: Novartis International AG: Revenue (by Region), $Million, 2019-2021
Figure 135: Novartis International AG: R&D Expenditure, $Million, 2019-2021
Figure 136: Novartis International AG: SWOT Analysis
Figure 137: Pfizer Inc.: Commercialized Therapy
Figure 138: Pfizer Inc.: Overall Financials, $Million, 2019-2021
Figure 139: Pfizer Inc.: Revenue (by Region), $Million, 2019-2021
Figure 140: Pfizer Inc.: R&D Expenditure, $Million, 2019-2021
Figure 141: Pfizer Inc.: SWOT Analysis
Figure 142: Takeda Pharmaceutical Company Limited: Pre-Clinical and Clinical Assets
Figure 143: Takeda Pharmaceutical Company Limited: Overall Financials, $Million, 2018-2020
Figure 144: Takeda Pharmaceutical Company Limited: Revenue (by Region), $Million, 2018-2020
Figure 145: Takeda Pharmaceutical Company Limited: R&D Expenditure, $Million, 2018-2020
Figure 146: Takeda Pharmaceutical Company Limited: SWOT Analysis
Figure 147: UCB S.A.: Commercialized Therapy
Figure 148: UCB S.A.: Pre-Clinical and Clinical Assets
Figure 149: UCB S.A.: Overall Financials, $Million, 2019-2021
Figure 150: UCB S.A.: Revenue (by Region), $Million, 2019-2021
Figure 151: UCB S.A.: R&D Expenditure, $Million, 2019-2021
Figure 152: UCB S.A.: SWOT Analysis
List of Tables
Table 1: Annual Cost of Approved Axial Spondyloarthritis Therapeutics in U.S.
Table 2: Likert Scale
Table 3: Impact Analysis of Market Drivers
Table 4: Impact Analysis of Market Restraints
Table 5: Approved Biologic Agents for Axial Spondyloarthritis (axSpA), (2020-2021)
Table 6: Approved Axial Spondyloarthritis Products in Developed Nations
Table 7: Axial Spondyloarthritis Drugs for Ankylosing Spondylitis
Table 8: Axial Spondyloarthritis Drugs for Non-radiographic Axial Spondyloarthritis
Table 9: List of Selective Axial Spondyloarthritis Commercialized Products in the U.S.
Table 10: List of Selective Axial Spondyloarthritis Commercialized Products in the EU4 + U.K.
Table 11: List of Selective Axial Spondyloarthritis Commercialized Products in Japan
Table 12: Taltz (Ixekizumab): Indications
Table 13: Simponi/Simponi Area (Golimumab): Indications
Table 14: Lumicef (Brodalumab/KHK4827): Indications
Table 15: Simponi (Golimumab): Indications
Table 16: Cosentyx (Secukinumab): Indications
Table 17: Xeljanz/Xeljanz XR: Indications
Table 18: Cimzia (Certolizumab?Pegol): Indications