Table of Content

1. Market Guides
1.1 Situation Analysis
1.2 Guide for Executives and Marketing Staff
1.3 Guide for Investment Analysts and Management Consultants

2. Introduction and Market Definition
2.1 What is Oligonucleotide Synthesis?
2.1.1 The Enzyme Race
2.1.2 Data Storage - The Elephant in the Room
2.2 Market Definition
2.2.1 Market Size
2.2.2 Currency
2.2.3 Years
2.3 Methodology
2.3.1 Authors
2.3.2 Sources
2.4 U.S. Medical Market and Pharmaceutical Research Spending - Perspective
2.4.1 U.S. Expenditures for Pharmaceutical Research
2.5 Perspective: Healthcare, the IVD Industry, and the COVID-19 Pandemic
2.5.1 Global Healthcare Spending
2.5.2 Spending on Diagnostics
2.5 Important Role of Insurance for Diagnostics

3. Oligonucleotide Synthesis
3.1 Synthesis Technology
3.2 Automation
3.3 Types of Oligonucleotides
3.4 PCR Primers
3.5 PCR Assays and Panels
3.6 Sequencing
3.7 DNA Microarrays
3.8 Fluorescence In Situ Hybridization (FISH)
3.9 Antisense Oligonucleotides
3.10 Other Uses of Oligonucleotides
3.11 Relationship to CRISPR and Gene Editing

4. Industry Overview
4.1 Players in a Dynamic Market
4.1.1 Academic Research Lab
4.1.2 Genome and Bio Foundries
4.1.3 Chemical and Food Product Supplier
4.1.4 Synthetic Gene and Oligo Supplier
4.1.5 Diagnostic Manufacturer
4.1.6 Pharmaceutical Company
4.1.7 Audit Body

5. Market Factors
5.1 Factors Driving Growth
5.1.1 The Role of Diagnostics and the Covid Effect
5.1.2 The RNA Based Vaccine
5.1.3 Genomic Blizzard
5.1.4 Antisense Revival
5.1.5 New Applications
5.2 Factors Limiting Growth
5.2.1 Declining Price
5.2.2 Technology Lag
5.2.3 COVID Realignment
5.3 The Next Five Years

6. Oligonucleotide Synthesis Recent Developments
6.1 Recent Developments - Importance and How to Use This Section
6.1 Importance of These Developments
6.1.2 How to Use This Section
6.2 New Rapid Multiplexed PCR Assay Uses Oligo Probes
6.3 MIT Devises Oligo 'File System' for DNA Data Storage
6.4 Nuclera Acquires E Ink Digital Microfluidics Business
6.5 Twist Bioscience Hits Milestone for DNA Data Storage
6.6 Twist Bioscience, Vivlion Partner on RNA Libraries for CRISPR
6.7 DNA Script Launching Benchtop Synthesizer for 'DNA on Demand'
6.8 RNA Disease Dx to Develop PoC Covid Test
6.9 Evonetix and Analog Devices Develop GEN3 DNA Synthesis Platform
6.10 ATDBio Receives Grant for Cancer Diagnosis Project
6.11 Twist Bioscience Announces SARS-CoV-2 Therapeutic Ab
6.12 Drugmakers boost oligo capacity amid Covid-19
6.13 Aligos Therapeutics in Study of Oligo Candidate
6.14 DNA Script Raises $89M for SYNTAX Launch
6.15 Codexis & Molecular Assemblies Partner for DNA Synthesis
6.16 NuProbe Licenses Oligo Technology from Rice
6.17 Genome editing with Cas9-oligo conjugates
6.18 OliX Pharma and AM Chemicals Partner for RNA Synthesis Support
6.19 Twist Bio To Pay $22.5M To End Trade Secrets Suit
6.20 DNA Script, partners get grant for data storage
6.21 Xi’s STA unit opens oligonucleotide plant
6.22 Agilent Doubles Capacity to Produce Oligos
6.23 GeneDesign Opens Oligo Development Center

7. Profiles of Key Companies
7.1 Abbott Diagnostics
7.2 Ajinomoto Bio-Pharma
7.3 Alnylam Pharmaceuticals
7.4 Amyris
7.5 Ansa BioTechnologies
7.6 ATDBio
7.7 ATG biosynthetics
7.8 ATUM
7.9 Bayer
7.10 Beckman Coulter Diagnostics
7.11 Becton, Dickinson and Company
7.12 Biomatik
7.13 bioMérieux Diagnostics
7.14 Bio-Rad Laboratories, Inc.
7.15 Bio-Synthesis
7.16 Blue Heron Biotechnology (Eurofins Genomic)
7.17 Camena Bioscience
7.18 Cepheid (Danaher)
7.19 Codexis
7.20 Diasorin S.p.A.
7.21 DNA Script
7.22 Enzo Life Sciences, Inc.
7.23 Eurofins Scientific
7.24 Eurogentec (Kaneka)
7.25 Evonetix
7.26 GE Healthcare
7.27 Genomatica
7.28 Genscript Biotech
7.29 Hologic
7.30 Integrated DNA Technologies(Danaher)
7.31 Ionis Pharmaceuticals
7.32 Janssen Diagnostics
7.33 Kern Systems
7.34 LGC Biosearch Technologies
7.35 Maravai LifeSciences Holdings
7.36 Merck & Co., Inc
7.37 Microsynth
7.38 Millipore Sigma
7.39 Molecular Assemblies
7.40 Nitto Denko(Avecia)
7.41 Nuclera
7.42 Perkin Elmer
7.43 Primerdesign(Novacyt)
7.44 Qiagen Gmbh
7.45 Roche Molecular Diagnostics
7.46 Seegene
7.47 Siemens Healthineers
7.48 Synthego
7.49 Thermo Fisher Scientific Inc
7.50 Twist Bioscience

8. Oligonucleotide Synthesis Global Market Overview
8.1 Global Market Overview by Country
8.1.1 Table - Global Market by Country
8.1.2 Chart - Global Market by Country
8.2 Global Market Size by Length - Overview
8.2.1 Table - Global Market by Length
8.2.2 Chart - Global Market by Length - Base/Final Year Comparison
8.2.3 Chart - Global Market by Length - Base Year
8.2.4 Chart - Global Market by Length - Final Year
8.2.5 Chart - Global Market by Length - Share by Year
8.2.6 Chart - Global Market by Length - Segment Growth
8.3 Global Market Size by Application - Overview
8.3.1 Table - Global Market by Application
8.3.2 Chart - Global Market by Application - Base/Final Year Comparison
8.3.3 Chart - Global Market by Application - Base Year
8.3.4 Chart - Global Market by Application - Final Year
8.3.5 Chart - Global Market by Application - Share by Year
8.3.6 Chart - Global Market by Application - Segment Growth
8.4 Global Market Size by Product - Overview
8.4.1 Table - Global Market by Product
8.4.2 Chart - Global Market by Product - Base/Final Year Comparison
8.4.3 Chart - Global Market by Product - Base Year
8.4.4 Chart - Global Market by Product - Final Year
8.4.5 Chart - Global Market by Product - Share by Year
8.4.6 Chart - Global Market by Product - Segment Growth

9. Global Market by Length
9.1 <20 mer Market
9.1.1 Table - <20 mer Market by Country
9.1.2 Chart - <20 mer Market Segment Growth
9.2 21-50 mer Market
9.2.1 Table - 21-50 mer Market by Country
9.2.2 Chart - 21-50 mer Market Segment Growth
9.3 51-100 mer Market
9.3.1 Table - 51-100 mer Market by Country
9.3.2 Chart - 51-100 mer Market Segment Growth
9.4 >100 mer Market
9.4.1 Table - >100 mer Market by Country
9.4.2 Chart - >100 mer Market Segment Growth

10. Global Market by Application
10.1 Research Market
10.1.1 Table - Research Market by Country
10.1.2 Chart - Research Market Segment Growth
10.2 Diagnostics Market
10.2.1 Table - Diagnostics Market by Country
10.2.2 Chart - Diagnostics Market Segment Growth
10.3 Therapeutics Market
10.3.1 Table - Therapeutics Market by Country
10.3.2 Chart - Therapeutics Market Segment Growth
10.4 Data Market
10.4.1 Table - Data Market by Country
10.4.2 Chart - Data Market Segment Growth

11. Global Market by Product
11.1 Oligonucleotides Market
11.1.1 Table - Oligonucleotides Market by Country
11.1.2 Chart - Oligonucleotides Market Segment Growth
11.2 Instruments Market
11.2.1 Table - Instruments Market by Country
11.2.2 Chart - Instruments Market Segment Growth
11.3 Reagents Market
11.3.1 Table - Reagents Market by Country
11.3.2 Chart - Reagents Market Segment Growth

12. Appendices
12.1 Typical Oligo Synthesis Price Lists
12.2 Medicare Clinical Lab Fee Schedule 2021
12.3 Share of Pharma R&D by Country

List of Tables
Table 1 Companies Formed to Exploit Enzyme Synthesis
Table 2 Market Players by Type
Table 3 Five Factors Driving Growth
Table 4 Three Factors Limiting Growth
Table 5 Global Market by Country/Region
Table 6 Global Market by Length
Table 7 Global Market by Application
Table 8 Global Market by Product
Table 9 <20 mer Market by Country
Table 10 21-50 mer Market by Country
Table 11 51-100 mer Market by Country
Table 12 >100 mer Market by Country
Table 13 Research Market by Country
Table 14 Diagnostics Market by Country
Table 15 Therapeutics Market by Country
Table 16 Data Market by Country
Table 17 Oligonucleotides Market by Country
Table 18 Instruments Market by Country
Table 19 Reagents Market by Country
Table 20 2021 Clinical Lab Fee Schedule

List of Figures
Figure 1 Pharmaceutical Research Spending Global, USA & China
Figure 2 Map of Global Healthcare Spending Per Capita
Figure 3 Wholesale vs. Retail Diagnostic Spending
Figure 4 Phosphoramidites Structure
Figure 5 DNA/Oligonucleotide Synthetic Cycle
Figure 6 Growth rates of Oligionucleotide Synthesis by Application
Figure 7 Market Size by Country
Figure 8 Global Market by Length - Base vs. Final Year
Figure 9 Length Market Base Year
Figure 10 Length Market Final Year
Figure 11 Length Share by Year
Figure 12 Length Segment Growth
Figure 13 Global Market by Application - Base vs. Final Year
Figure 14 Application Market Base Year
Figure 15 Application Market Final Year
Figure 16 Application Share by Year
Figure 17 Application Segment Growth
Figure 18 Global Market by Product - Base vs. Final Year
Figure 19 Product Market Base Year
Figure 20 Product Market Final Year
Figure 21 Product Share by Year
Figure 22 Product Segment Growth
Figure 23 Chart - <20 mer Market Growth
Figure 24 Chart 21-50 mer Market Growth
Figure 25 Chart - 51-100 mer Market Growth
Figure 26 Chart - >100 mer Market Growth
Figure 27 Chart Research Market Growth
Figure 28 Chart - Diagnostics Market Growth
Figure 29 Chart - Therapeutics Market Growth
Figure 30 Chart - Therapeutics market Growth
Figure 31 Chart - Data Market Growth
Figure 32 Chart Oligonucleotides Market Growth
Figure 33 Chart - Instruments Market Growth
Figure 34 Chart - Reagents Market Growth
Figure 35 Eurofins Price List
Figure 36 Hokkaido System Science Co. Price List
Figure 37 Biobasic Price List
Figure 38 Share of Pharma R&D by Country