Table of Content

Market Guides

  • Situation Analysis & COVID-19 Impact
  • Guide for Executives and Marketing Staff
  • Guide for Investment Analysts and Management Consultants

1. Introduction and Market Definition
1.1 What are Cell Based Assays?
1.2 Clinical Trial Failures
1.2.1 Immuno-oncology Plays a Leading Role in Cell Based Assays
1.2.2 Infectious Disease Will Play a Larger Role
1.3 Market Definition
1.3.1 Market Size
1.3.2 Currency
1.3.3 Years
1.4 Methodology
1.4.1 Authors
1.4.2 Sources
1.5 U.S. Medical Market and Pharmceutical Research Spending - Perspective
1.5.1 U.S. Expenditures for Pharmaceutical Research

2. Cell Based Assays - Guide to Technology
2.1 Cell Cultures
2.1.1 Cell Lines
2.1.2 Primary Cells
2.1.3 Stem Cells
2.1.3.1 iPSC’s - The Special Case
2.2 Cell Assays
2.3 Cell Viability Assays
2.3 Cell Proliferation Assays
2.4 Cytotoxicity Assays
2.5 Cell Senescence Assays
2.6 Apoptosis
2.7 Autophagy
2.8 Necrosis
2.9 Oxidative Stress
2.10 2D vs. 3D
2.11 Signalling Pathways, GPCR
2.12 Immune Regulation & Inhibition
2.13 Reporter Gene Technology
2.14 CBA Design & Development
2.15 Cell Based Assays - The Takeaway

3. Industry Overview
3.1 Players in a Dynamic Market
3.1.1 Academic Research Lab
3.1.2 Contract Research Organization
3.1.3 Genomic Instrumentation Supplier
3.1.5 Cell Line and Reagent Supplier
3.1.6 Pharmaceutical Company
3.1.7 Audit Body
3.1.8 Certification Body

4. Market Trends
4.1 Factors Driving Growth
4.1.1 Candidate Growth
4.1.2 Immuno-oncology
4.1.3 Genomic Blizzard
4.1.4 Technology Convergence
4.1.5 The Insurance Effect
4.2 Factors Limiting Growth
4.2.1 CBA Development Challenges
4.2.2 Instrument Integration
4.2.3 Protocols
4.3 Technology Development
4.3.1 3D Assays
4.3.2 Automation
4.3.3 Software
4.3.4 Primary Cells
4.3.5 Signalling and Reporter Genes
4.3.6 The Next Five Years

5. Cell Based Assays Recent Developments
5.1 Recent Developments - Importance and How to Use This Section
5.1.1 Importance of These Developments
5.1.2 How to Use This Section

  • Axxam and FUJIFILM Cellular Dynamics Announce Strategic Alliance
  • Cancer Genetics to Acquire Organoid Startup Stemonix
  • Curi Bio Acquires Artificial Intelligence Firm Dana Solutions
  • CRISPR Screens Uncover Novel Cancer Therapy Targets
  • ERS Genomics Licenses CRISPR-Cas9 Patents to Axxam
  • New Transcriptomics Assay Facilitates Compound Screens
  • Carta Biosciences Betting on Gene Interaction Mapping
  • High-throughput Identifies cancer drug candidates
  • Velabs Therapeutics partners with Alytas Therapeutics to develop a novel immune-based therapy for obesity
  • InSphero platform selected to test Cyclerion's sGC stimulator technology
  • OcellO to provide in vitro research services to Merus
  • Charles River Laboratories to acquire Citoxlab
  • Reaction Biology Corporation Purchases ProQinase GmbH
  • Cisbio extends its assay portfolio for immuno-oncology drug discovery
  • STEMCELL Technologies Launches Next-Generation Culture System
  • Abcam Acquires Calico Biolabs
  • Evotec announces achievement in Celgene alliance utilizing IPSC
  • screening
  • Fujifilm Cellular Dynamics Inc. launches iCELL Microglia
  • Cisbio and Excellerate Bioscience partner
  • Horizon Discovery extends CRISPR Screening Service to primary human T cells

6. Profiles of Key Cell Based Assay Companies

  • Abcam
  • Agilent
  • Aurora Instruments Ltd
  • Axxam
  • Beckman Coulter Diagnostics
  • Becton, Dickinson and Company
  • BioIVT
  • Bio-Rad Laboratories, Inc.
  • BioTek Instruments
  • BioVision, Inc.
  • BMG Labtech
  • Cell Biolabs, Inc
  • Cell Signaling Technology, Inc.
  • Charles River Laboratories
  • Cisbio Bioassays
  • Corning, Inc
  • Cytovale
  • Enzo Life Sciences, Inc
  • Eurofins DiscoverX Corporation
  • Evotec AG
  • Excellerate Bioscience
  • Fujifilm Cellular Dynamics International
  • Genedata
  • Hemogenix
  • Horizon Discovery
  • Invivogen
  • Leica Biosystems
  • Lonza Group Ltd.
  • Luminex Corp
  • Merck & Co., Inc
  • Miltenyi Biotec
  • Molecular Devices
  • Nanion
  • Ncardia
  • New England Biolabs, Inc
  • Olympus
  • Origene Technologies
  • Perkin Elmer
  • Promega
  • Qiagen Gmbh
  • Reaction Biology
  • Recursion Pharma
  • Roche Diagnostics
  • Sartorius
  • Sartorius-ForteBio
  • Sartorius-IntelliCyt
  • Sony Biotechnology
  • SPT Labtech
  • Stemcells Technologies Canada Inc
  • Tecan
  • Thermo Fisher Scientific Inc.
  • Vitro Biopharma

7. Global Market Size
7.1 Global Market Overview by Country
7.1.1 Table - Global Market by Country
7.1.2 Chart - Global Market by Country
7.2 Global Market by User - Overview
7.2.1 Table - Global Market by User
7.2.2 Chart - Global Market by User - Base/End Year Comparison
7.2.3 Chart - Global Market by User - Base Year
7.2.4 Chart - Global Market by User - End Year
7.2.5 Chart - Global Market by User - Share by Year
7.3 Global Market by Product Class - Overview
7.3.1 Table - Global Market by Product Class
7.3.2 Chart - Global Market by Product Class - Base/End Year Comparison
7.3.3 Chart - Global Market by Product Class - Base Year
7.3.4 Chart - Global Market by Product Class - End Year
7.3.5 Chart - Global Market by Product Class - Share by Year

8. Global Market by User Type
8.1 Pharma
8.1.1 Table Pharma - by Country
8.1.2 Chart - Pharma Growth
8.2 Research
8.2.1 Table Research - by Country
8.2.2 Chart - Research Growth
8.3 Industry/Cosmetic
8.3.1 Table Industry/Cosmetic - by Country
8.3.2 Chart - Industry/Cosmetic Growth

9. Cell Based Assay by Product Class
9.1 Instrument
9.1.1 Table Instrument - by Country
9.1.2 Chart - Instrument Growth
9.2 Reagent
9.2.1 Table Reagent - by Country
9.2.2 Chart - Reagent Growth
9.3 Services
9.3.1 Table Services - by Country
9.3.2 Chart - Services Growth
9.4 Software
9.4.1 Table Software - by Country
9.4.2 Chart - Software Growth

10. Appendices
10.1 FDA Cancer Drug Approvals by Year
10.2 Clinical Trials Started 2010 to 2016
10.3 Share of Pharma R&D by Country

List of Tables
Table 1 The Large Variety of Cell Lines
Table 2 Some Common Viability Assays
Table 3 Oxidative Stress Related Diseases
Table 4 Important Signalling Pathways
Table 5 Market Players by Type
Table 6 Five Factors Driving Growth
Table 7 Three Factors Limiting Growth
Table 8 Global Market by Region
Table 9 Global Market by User
Table 10 Global Market by Product Class
Table 11 Pharma by Country
Table 12 Research by Country
Table 13 Industry/Cosmetic by Country
Table 14 Instrument by Country
Table 15 Reagent by Country
Table 16 Services by Country
Table 17 Software by Country

List of Figures
Figure 1 Reasons for clinical Failure by Phase
Figure 2 Immunotherapy Clinical Trial Growth
Figure 3 Pharmaceutical Research Expenditures 2001 to 2017 ($Billion)
Figure 4 Oxidative Stress and Free Radical Toxicity
Figure 5 FDA Cancer Drug Approvals
Figure 6 Growth rates of Cell Based Assays by Product Class
Figure 7 Global Market Share Chart
Figure 8 Global Market by User - Base vs. End Year
Figure 9 Global Market by User Base Year
Figure 10 Global Market by User End Year
Figure 11 User Share by Year
Figure 12 Global Market by Product Class - Base vs. End Year
Figure 13 Global Market by Product Class Base Year
Figure 14 Global Market by Product Class End Year
Figure 15 Product Class Share by Year
Figure 16 Pharma Growth
Figure 17 Research Growth
Figure 18 Industry/Cosmetic Growth
Figure 19 Instrument Growth
Figure 20 Reagent Growth
Figure 21 Services Growth
Figure 22 Software Growth
Figure 23 FDA Cancer Drug Approvals by Year
Figure 24 Clinical Trials for Immunotherapy by Year
Figure 25 Share of Pharma R&D by Country