Table of Content

1. Key Insights

2. Sj?gren’s Syndrome (SS): Epidemiology Overview at a Glance
2.1. Patient Share (%) Distribution of SS in 2017
2.2. Patient Share (%) Distribution of SS in 2030

3. Organizations

4. Executive summary

5. Disease Overview: Sj?gren’s syndrome
5.1. Introduction
5.2. Classification of Sjogren’s Syndrome
5.3. Signs and Symptoms
5.4. Etiology
5.5. Pathogenesis
5.6. Biomarkers in Sjogren’s Syndrome
5.7. Diagnosis of Sjogren’s Syndrome
5.7.1. Differential Diagnosis

6. Epidemiology and Patient Population
6.1. Key Findings
6.2. 7MM Total Diagnosed Prevalent Patient Population of Sj?gren’s Syndrome
6.3. Country Wise-Epidemiology of Sj?gren’s syndrome
6.4. United States
6.4.1. Assumptions and Rationale
6.4.2. Diagnosed Prevalent Cases of Sj?gren’s syndrome in the United States
6.4.3. Gender-Specific Cases of Sj?gren’s syndrome in the US
6.4.4. Type-Specific Cases of Sj?gren’s syndrome in the US
6.4.5. Severity-Specific Cases of Sj?gren’s syndrome in the US
6.5. Germany
6.5.1. Assumptions and Rationale
6.5.2. Diagnosed Prevalent Cases of Sj?gren’s syndrome in Germany
6.5.3. Gender-Specific Cases of Sj?gren’s syndrome in Germany
6.5.4. Type-Specific Cases of Sj?gren’s syndrome in Germany
6.5.5. Severity-Specific Cases of Sj?gren’s syndrome in Germany
6.6. France
6.6.1. Assumptions and Rationale
6.6.2. Diagnosed Prevalent Cases of Sj?gren’s syndrome in France
6.6.3. Gender-Specific Cases of Sj?gren’s syndrome in France
6.6.4. Type-Specific Cases of Sj?gren’s syndrome in France
6.6.5. Severity-Specific Cases of Sj?gren’s syndrome in France
6.7. Italy
6.7.1. Assumptions and Rationale
6.7.2. Diagnosed Prevalent Cases of Sj?gren’s syndrome in Italy
6.7.3. Gender-Specific Cases of Sj?gren’s syndrome in Italy
6.7.4. Type-Specific Cases of Sj?gren’s syndrome in Italy
6.7.5. Severity-Specific Cases of Sj?gren’s syndrome in Italy
6.8. Spain
6.8.1. Assumptions and Rationale
6.8.2. Diagnosed Prevalent Cases of Sj?gren’s syndrome in Spain
6.8.3. Gender-Specific Cases of Sj?gren’s syndrome in Spain
6.8.4. Type-Specific Cases of Sj?gren’s syndrome in Spain
6.8.5. Severity-Specific Cases of Sj?gren’s syndrome in Spain
6.9. United Kingdom
6.9.1. Assumptions and Rationale
6.9.2. Diagnosed Prevalent Cases of Sj?gren’s syndrome in the United Kingdom
6.9.3. Gender-Specific Cases of Sj?gren’s syndrome in the United Kingdom
6.9.4. Type-Specific Cases of Sj?gren’s syndrome in the UK
6.9.5. Severity-Specific Cases of Sj?gren’s syndrome in the United Kingdom
6.10. Japan
6.10.1. Assumptions and Rationale
6.10.2. Diagnosed Prevalent Cases of Sj?gren’s syndrome in Japan
6.10.3. Gender-Specific Cases of Sj?gren’s syndrome in Japan
6.10.4. Type-Specific Cases of Sj?gren’s syndrome in Japan
6.10.5. Severity-Specific Cases of Sj?gren’s syndrome in Japan

7. Current Treatment Practices
7.1. United States Treatment Guidelines for Sj?gren’s Disease
7.2. Evidence-based medicine clinical practice guidelines (US, EU, JP)

8. Unmet Needs

9. SWOT Analysis

10. KOL Views

11. Appendix

12. Report Methodology

13. DelveInsight Capabilities

14. Disclaimer

15. About DelveInsight



List of Figures


Figure 1: Clinical spectrum Sjogren’s syndrome
Figure 2: The Pathogenesis of autoimmune epitelitis as a potential explanation for Sjogren’s Syndrome
Figure 3: Interplay of immune and non-immune factors in the pathophysiology of Sjogren’s Syndrome
Figure 4: Diagnosed Prevalent Patient Population of Sj?gren’s syndrome in 7MM (2017–2030)
Figure 5: Diagnosed Prevalent Cases of Sj?gren’s syndrome in the United States (2017–2030)
Figure 6: Gender-specific Diagnosed Prevalent Cases of Sj?gren’s syndrome in the US (2017–2030)
Figure 7: Type-specific Diagnosed Prevalent Cases of Sj?gren’s syndrome in the US (2017–2030)
Figure 8: Severity-specific Cases of Sj?gren’s syndrome in the US (2017–2030)
Figure 9: Diagnosed Prevalent Cases of Sj?gren’s syndrome in Germany (2017–2030)
Figure 10: Gender-specific of Sj?gren’s syndrome in Germany (2017–2030)
Figure 11: Type-specific Diagnosed Prevalent Cases of Sj?gren’s syndrome in Germany (2017–2030)
Figure 12: Severity specific Cases of Sj?gren’s syndrome in Germany (2017–2030)
Figure 13: Diagnosed Prevalent Cases of Sj?gren’s syndrome in France (2017–2030)
Figure 14: Gender-specific Cases of Sj?gren’s syndrome in France (2017–2030)
Figure 15: Type-specific Diagnosed Prevalent Cases of Sj?gren’s syndrome in France (2017–2030)
Figure 16: Severity specific Cases of Sj?gren’s syndrome in France (2017–2030)
Figure 17: Diagnosed Prevalent Cases of Sj?gren’s syndrome in Italy (2017–2030)
Figure 18: Gender-specific Cases of Sj?gren’s syndrome in Italy (2017–2030)
Figure 19: Type-specific Diagnosed Prevalent Cases of Sj?gren’s syndrome in Italy (2017–2030)
Figure 20: Severity specific Cases of Sj?gren’s syndrome in Italy (2017–2030)
Figure 21: Diagnosed Prevalent Cases of Sj?gren’s syndrome in Spain (2017–2030)
Figure 22: Gender-specific Cases of Sj?gren’s syndrome in Spain (2017–2030)
Figure 23: Type-specific Diagnosed Prevalent Cases of Sj?gren’s syndrome in Spain (2017–2030)
Figure 24: Severity specific Cases of Sj?gren’s syndrome in Spain (2017–2030)
Figure 25: Diagnosed Prevalent Cases of Sj?gren’s syndrome in the United Kingdom (2017–2030)
Figure 26: Gender-specific Cases of Sj?gren’s syndrome in the United Kingdom (2017–2030)
Figure 27: Type-specific Diagnosed Prevalent Cases of Sj?gren’s syndrome in the UK (2017–2030)
Figure 28: Severity specific Cases of Sj?gren’s syndrome in the UK (2017–2030)
Figure 29: Diagnosed Prevalent Cases of Sj?gren’s syndrome in Japan (2017–2030)
Figure 30: Gender-specific Cases of Sj?gren’s syndrome in Japan (2017–2030)
Figure 31: Type-specific Diagnosed Prevalent Cases of Sj?gren’s syndrome in Japan (2017–2030)
Figure 32: Severity -specific Cases of Sj?gren’s syndrome in Japan (2017–2030)
Figure 33: Unmet Needs of Sjogren’s syndrome


List of Tables


Table 1: American-European Consensus Group Criteria- Revised international classification criteria for Sj?gren’s syndrome
Table 2: Revised rules for classification - American-European Consensus Group Criteria
Table 3: ACR/EULAR criteria
Table 4: Selected Non-HLA genes implicated in SS
Table 5: Biomarkers in Primary Sjogren’s syndrome
Table 6: Diagnostic tests to evaluate sicca symptoms in patients with Sjogren’s Syndrome
Table 7: Evaluation of Dry Eye
Table 8: Comparison of the Revised AECG Classification criteria and the ACR Classification criteria for Sj?gren’s syndrome
Table 9: Diagnosed Prevalent Patient Population of Sj?gren’s syndrome in 7MM (2017–2030)
Table 10: Diagnosed Prevalent Cases of Sj?gren’s syndrome in the US (2017–2030)
Table 11: Gender-specific cases of Sj?gren’s syndrome in the US (2017–2030)
Table 12: Type-specific Cases of Sj?gren’s syndrome in the US (2017–2030)
Table 13: Severity specific Cases of Sj?gren’s syndrome in the United States (2017–2030)
Table 14: Diagnosed Prevalent Cases of Sj?gren’s syndrome in Germany (2017–2030)
Table 15: Gender-specific cases of Sj?gren’s syndrome in Germany (2017–2030)
Table 16: Type-specific Cases of Sj?gren’s syndrome in Germany (2017–2030)
Table 17: Severity specific Cases of Sj?gren’s syndrome in Germany (2017–2030)
Table 18: Diagnosed Prevalent Cases of Sj?gren’s syndrome in France (2017–2030)
Table 19: Gender-specific cases of Sj?gren’s syndrome in France (2017–2030)
Table 20: Type-specific Cases of Sj?gren’s syndrome in France (2017–2030)
Table 21: Severity specific Cases of Sj?gren’s syndrome in France (2017–2030)
Table 22: Diagnosed Prevalent Cases of Sj?gren’s syndrome in Italy (2017–2030)
Table 23: Gender-specific cases of Sj?gren’s syndrome in Italy (2017–2030)
Table 24: Type-specific Cases of Sj?gren’s syndrome in Italy (2017–2030)
Table 25: Severity specific Cases of Sj?gren’s syndrome in Italy (2017–2030)
Table 26: Diagnosed Prevalent Cases of Sj?gren’s syndrome in Spain (2017–2030)
Table 27: Gender-specific cases of Sj?gren’s syndrome in Spain (2017–2030)
Table 28: Type-specific Cases of Sj?gren’s syndrome in Spain (2017–2030)
Table 29: Severity specific Cases of Sj?gren’s syndrome in Spain (2017–2030)
Table 30: Diagnosed Prevalent Cases of Sj?gren’s syndrome in the UK (2017–2030)
Table 31: Gender-specific cases of Sj?gren’s syndrome in the UK (2017–2030)
Table 32: Type-specific Cases of Sj?gren’s syndrome in the UK (2017–2030)
Table 33: Severity specific Cases of Sj?gren’s syndrome in the UK (2017–2030)
Table 34: Diagnosed Prevalent Cases of Sj?gren’s syndrome in Japan (2017–2030)
Table 35: Gender-specific cases of Sj?gren’s syndrome in Japan (2017–2030)
Table 36: Type-specific Cases of Sj?gren’s syndrome in Japan (2017–2030)
Table 37: Severity specific Cases of Sj?gren’s syndrome in Japan (2017–2030)