Table of Content

1. Key Insights

2. Biliary Atresia: Patient Overview at a Glance
2.1. Patient Share (%) Distribution of Biliary Atresia in 2017
2.2. Patient Share (%) Distribution of Biliary Atresia in 2030

3. Executive summary

4. Organizations

5. Disease Overview: Biliary Atresia
5.1. Introduction
5.2. Signs and Symptoms
5.3. Classification of Biliary Atresia
5.3.1. Anatomical forms
5.3.2. Clinical phenotypes of Biliary Atresia
5.3.3. Kasai classification
5.4. Etiology and Pathogenesis
5.4.1. Pathogenesis
5.5. Diagnosis
5.5.1. Differential Diagnosis

6. Epidemiology and Patient Population
6.1. Key Findings
6.2. 7MM Total Incident Patient Population of Biliary Atresia
6.3. United States
6.3.1. Assumptions and Rationale
6.3.2. Total Incident Cases of Biliary Atresia in the United States
6.3.3. Type-specific Cases of Biliary Atresia in the United States
6.3.4. Gender-specific Cases of Biliary Atresia in the United States
6.4. EU-5
6.4.1. Assumptions and Rationale
6.5. Germany
6.5.1. Total Incident Cases of Biliary Atresia in Germany
6.5.2. Type-specific Cases of Biliary Atresia in Germany
6.5.3. Gender-specific Cases of Biliary Atresia in Germany
6.6. France
6.6.1. Total Incident Cases of Biliary Atresia in France
6.6.2. Type-specific Cases of Biliary Atresia in France
6.6.3. Gender-specific Cases of Biliary Atresia in France
6.7. Italy
6.7.1. Total Incident Cases of Biliary Atresia in Italy
6.7.2. Type-specific Cases of Biliary Atresia in Italy
6.7.3. Gender-specific Cases of Biliary Atresia in Italy
6.7.1. Total Incident Cases of Biliary Atresia in Italy
6.7.2. Type-specific Cases of Biliary Atresia in Italy
6.7.3. Gender-specific Cases of Biliary Atresia in Italy
6.8. Spain
6.8.1. Total Incident Cases of Biliary Atresia in Spain
6.8.2. Type-specific Cases of Biliary Atresia in Spain
6.8.3. Gender-specific Cases of Biliary Atresia in Spain
6.9. UK
6.9.1. Total Incident Cases of Biliary Atresia in the UK
6.9.2. Type-specific Cases of Biliary Atresia in the UK
6.9.3. Gender-specific Cases of Biliary Atresia in the UK
6.10.Japan
6.10.1. Assumptions and Rationale
6.10.2. Total Incident Cases of Biliary Atresia in Japan
6.10.3. Type-specific Cases of Biliary Atresia in Japan
6.10.4. Gender-specific Cases of Biliary Atresia in Japan

7. Current Treatment Practices

8. Unmet needs

9. SWOT Analysis

10. Bibliography

11. Appendix
11.1 Report Methodology

12. DelveInsight Capabilities

13. Disclaimer

14. About DelveInsight



List of Figures


Figure 1: Signs and Symptoms
Figure 2: Clincal Phenotypes of BA
Figure 3: Classification of biliary atresia according to Kasai classification system
Figure 4: Schematic of the hypothesis of biliary atresia etiology
Figure 5: Etiology and Pathogenesis
Figure 6: Innate immune receptors present in Cholangiocytes
Figure 7: Mechanism of obstruction in biliary atresia
Figure 8: Disease progression mechanisms after bile duct obstruction
Figure 9: Total Incident Patient Population of Biliary Atresia in 7MM (2017-2030)
Figure 10: Total Incident cases of Biliary Atresia in the United States (2017–2030)
Figure 11: Type-specific cases of Biliary Atresia in the US (2017-2030)
Figure 12: Gender-specific cases of Biliary Atresia in the United States (2017-2030)
Figure 13: Total Incident cases of Biliary Atresia in Germany (2017–2030)
Figure 14: Type-specific cases of Biliary Atresia in the Germany 2017-2030)
Figure 15: Gender-specific cases of Biliary Atresia in Germany (2017-2030)
Figure 16: Total Incident cases of Biliary Atresia in France (2017–2030)
Figure 17: Type-specific cases of Biliary Atresia in the France 2017-2030)
Figure 18: Gender-specific cases of Biliary Atresia in France (2017-2030)
Figure 19: Total Incident cases of Biliary Atresia in Italy (2017–2030)
Figure 20: Type-specific cases of Biliary Atresia in the Italy 2017-2030)
Figure 21: Gender-specific cases of Biliary Atresia in Italy (2017-2030)
Figure 22: Total Incident cases of Biliary Atresia in Spain (2017–2030)
Figure 23: Type-specific cases of Biliary Atresia in the Spain 2017-2030)
Figure 24: Gender-specific cases of Biliary Atresia in Spain (2017-2030)


List of Tables


Table 1: Anatomical types of biliary atresia (BA)
Table 2: Clinical phenotypes of Biliary Atresia
Table 3: Total Incident Patient Population of Biliary Atresia in 7MM (2017-2030)
Table 4: Total Incident cases of Biliary Atresia in the United States (2017-2030)
Table 5: Type-specific cases of Biliary Atresia in the United States (2017-2030)
Table 6: Gender-specific cases of Biliary Atresia in the United States (2017-2030)
Table 7: Total Incident cases of Biliary Atresia in Germany (2017-2030)
Table 8: Type-specific cases of Biliary Atresia in Germany (2017-2030)
Table 9: Gender-specific cases of Biliary Atresia in Germany (2017-2030)
Table 10: Total Incident cases of Biliary Atresia in France (2017-2030)
Table 11: Type-specific cases of Biliary Atresia in France (2017-2030)
Table 12: Gender-specific cases of Biliary Atresia in the France (2017-2030)
Table 13: Total Incident cases of Biliary Atresia in Italy (2017-2030)
Table 14: Type-specific cases of Biliary Atresia in Italy (2017-2030)
Table 15: Gender-specific cases of Biliary Atresia in Italy (2017-2030)
Table 16: Total Incident cases of Biliary Atresia in Spain (2017-2030)
Table 17: Type-specific cases of Biliary Atresia in Spain (2017-2030)
Table 18: Gender-specific cases of Biliary Atresia in Spain (2017-2030)
Table 19: Total Incident cases of Biliary Atresia in the UK (2017-2030)
Table 20: Type-specific cases of Biliary Atresia in the UK (2017-2030)
Table 21: Gender-specific cases of Biliary Atresia in the UK (2017-2030)
Table 22: Total Incident cases of Biliary Atresia in Japan (2017-2030)
Table 23: Type-specific cases of Biliary Atresia in Japan (2017-2030)
Table 24: Gender-specific cases of Biliary Atresia in Japan (2017-2030)