Table of Content

1 Introduction 7
1.1 Industry Definition and Research Scope 7
1.1.1 Industry Definition 7
1.1.2 Research Scope 8
1.2 Research Methodology 11
1.2.1 Overview of Market Research Methodology 11
1.2.2 Market Assumption 12
1.2.3 Secondary Data 12
1.2.4 Primary Data 12
1.2.5 Data Filtration and Model Design 14
1.2.6 Market Size/Share Estimation 15
1.2.7 Research Limitations 16
1.3 Executive Summary 17

2 Market Overview and Dynamics 20
2.1 Market Size and Forecast 20
2.1.1 Impact of COVID-19 on the Market 25
2.2 Major Growth Drivers 27
2.3 Market Restraints and Challenges 32
2.4 Emerging Opportunities and Market Trends 37
2.5 Porter’s Fiver Forces Analysis 41

3 Segmentation of North America Market by System Component 45
3.1 Market Overview by System Component 45
3.2 Data Collection Tools 47
3.2.1 Digital Platforms 49
3.2.2 Mobile Apps 50
3.2.3 Desktop-based Software 51
3.2.4 Wearables 52
3.2.5 Biosensors 53
3.3 Data Integration Systems 54

4 Segmentation of North America Market by Therapeutic Area 55
4.1 Market Overview by Therapeutic Area 55
4.2 Cardiovascular Diseases 57
4.3 Neurodegenerative Disorders 58
4.3.1 Parkinson’s Disease 60
4.3.2 Multiple Sclerosis 61
4.3.3 Alzheimer’s Disease 62
4.4 Sleep and Movement Diseases 63
4.5 Psychiatric Disorders 64
4.6 Chronic Pain 65
4.7 Gastrointestinal Diseases 66
4.8 Diabetes 67
4.9 Respiratory Conditions 68
4.10 Other Diseases 69

5 Segmentation of North America Market by Application 70
5.1 Market Overview by Application 70
5.2 Wellness 72
5.3 Disease Diagnosis 73
5.4 Personalised Medication 74
5.5 Drug Discovery and Development 75

6 Segmentation of North America Market by Development Status 77
6.1 Market Overview by Development Status 77
6.2 Novel Digital Biomarkers 80
6.3 Original Digital Biomarkers 81
6.4 Approved Digital Biomarkers 82

7 Segmentation of North America Market by End User 83
7.1 Market Overview by End User 83
7.2 Biopharmaceutical Companies & Labs 85
7.3 Healthcare Providers 86
7.4 Insurance Payers 87

8 North America Market 2019-2030 by Country 88
8.1 Overview of North America Market 88
8.2 U.S. 91
8.3 Canada 95
8.4 Mexico 97

9 Competitive Landscape 99
9.1 Overview of Key Vendors 99
9.2 New Product Launch, Partnership, Investment, and M&A 103
9.3 Company Profiles 104
Actigraph LLC 104
Akili Interactive Labs 106
AliveCor Inc 107
Altoida Inc 108
Amgen Inc 109
Bayer AG 110
Biogen Inc 111
Cambridge Cognition Plc 112
Eli Lilly and Company 113
Evidation Health, Inc. 114
F. Hoffmann-La Roche Ltd 115
Fitbit Inc 116
GlaxoSmithKline Plc 117
Happify Health 118
Human API 119
IXICO Plc 120
Koninklijke Philips N.V. 121
Medical Care Corporation 122
Medopad Ltd 123
Mindstrong Health 124
Neurotrack Technology, Inc 125
Novartis International AG 126
Pfizer Inc. 127
Quanterix Corporation 128
Sanofi S.A. 129
The Takeda Pharmaceuticals Company Limited 130
Verily Life Sciences 131
Winterlight Labs Inc. 132

10 Investing in North America Market: Risk Assessment and Management 133
10.1 Risk Evaluation of North America Market 133
10.2 Critical Success Factors (CSFs) 136
Related Reports and Products 139



List of Figures


Figure 1. Research Method Flow Chart 11
Figure 2. Breakdown of Primary Research 13
Figure 3. Bottom-up Approach and Top-down Approach for Market Estimation 15
Figure 4. North America Market Forecast in Optimistic, Conservative and Balanced Perspectives, 2019-2030 17
Figure 5. North America Digital Biomarkers Market, 2019-2030, $ mn 20
Figure 6. Category and Relationship of Traditional Biomarkers and Digital Biomarkers 21
Figure 7. Benefits and Challenges of Digital Biomarkers 23
Figure 8. North America Biomarkers Market, 2019-2030, $ mn 24
Figure 9. Share of Digital Biomarkers in Total Biomarkers Market, 2019-2030 24
Figure 10. Impact of COVID-19 on Business 25
Figure 11. Primary Drivers and Impact Factors of North America Digital Biomarkers Market 27
Figure 12. World 5G Traffic, 2019-2030, EB/year 30
Figure 13. Primary Restraints and Impact Factors of North America Digital Biomarkers Market 32
Figure 14. Data Security Risk in Various User Groups of Digital Biomarkers 35
Figure 15. Pathway to Regulatory Approval of Digital Biomarkers 36
Figure 16. Investment Opportunity Analysis 38
Figure 17. Porter’s Fiver Forces Analysis of North America Digital Biomarkers Market 41
Figure 18. Breakdown of North America Digital Biomarkers Market by System Component, 2019-2030, % of Revenue 46
Figure 19. North America Addressable Market Cap in 2020-2030 by System Component, Value ($ mn) and Share (%) 46
Figure 20. North America Digital Biomarkers Market: Data Collection Tools, 2019-2030, $ mn 47
Figure 21. North America Digital Biomarkers Market: Digital Platforms, 2019-2030, $ mn 49
Figure 22. North America Digital Biomarkers Market: Mobile Apps, 2019-2030, $ mn 50
Figure 23. North America Digital Biomarkers Market: Desktop-based Software, 2019-2030, $ mn 51
Figure 24. North America Digital Biomarkers Market: Wearables, 2019-2030, $ mn 52
Figure 25. North America Digital Biomarkers Market: Biosensors, 2019-2030, $ mn 53
Figure 26. North America Digital Biomarkers Market: Data Integration Systems, 2019-2030, $ mn 54
Figure 27. Breakdown of North America Digital Biomarkers Market by Therapeutic Area, 2019-2030, % of Sales Revenue 56
Figure 28. North America Addressable Market Cap in 2020-2030 by Therapeutic Area, Value ($ mn) and Share (%) 56
Figure 29. North America Digital Biomarkers Market: Cardiovascular Diseases, 2019-2030, $ mn 57
Figure 30. North America Digital Biomarkers Market: Neurodegenerative Disorders, 2019-2030, $ mn 58
Figure 31. North America Digital Biomarkers Market: Parkinson’s Disease, 2019-2030, $ mn 60
Figure 32. North America Digital Biomarkers Market: Multiple Sclerosis, 2019-2030, $ mn 61
Figure 33. North America Digital Biomarkers Market: Alzheimer’s Disease, 2019-2030, $ mn 62
Figure 34. North America Digital Biomarkers Market: Sleep and Movement Diseases, 2019-2030, $ mn 63
Figure 35. North America Digital Biomarkers Market: Psychiatric Disorders, 2019-2030, $ mn 64
Figure 36. North America Digital Biomarkers Market: Chronic Pain, 2019-2030, $ mn 65
Figure 37. North America Digital Biomarkers Market: Gastrointestinal Diseases, 2019-2030, $ mn 66
Figure 38. North America Digital Biomarkers Market: Diabetes, 2019-2030, $ mn 67
Figure 39. North America Digital Biomarkers Market: Respiratory Conditions, 2019-2030, $ mn 68
Figure 40. North America Digital Biomarkers Market: Other Diseases, 2019-2030, $ mn 69
Figure 41. Breakdown of North America Digital Biomarkers Market by Application, 2019-2030, % of Sales Revenue 71
Figure 42. North America Addressable Market Cap in 2020-2030 by Application, Value ($ mn) and Share (%) 71
Figure 43. North America Digital Biomarkers Market: Wellness, 2019-2030, $ mn 72
Figure 44. North America Digital Biomarkers Market: Disease Diagnosis, 2019-2030, $ mn 73
Figure 45. North America Digital Biomarkers Market: Personalised Medication, 2019-2030, $ mn 74
Figure 46. North America Digital Biomarkers Market: Drug Discovery and Development, 2019-2030, $ mn 75
Figure 47. Classification of Digital Biomarkers by Development Status 77
Figure 48. Breakdown of North America Digital Biomarkers Market by Development Status, 2019-2030, % of Revenue 79
Figure 49. North America Addressable Market Cap in 2020-2030 by Development Status, Value ($ mn) and Share (%) 79
Figure 50. North America Digital Biomarkers Market: Novel Digital Biomarkers, 2019-2030, $ mn 80
Figure 51. North America Digital Biomarkers Market: Original Digital Biomarkers, 2019-2030, $ mn 81
Figure 52. North America Digital Biomarkers Market: Approved Digital Biomarkers, 2019-2030, $ mn 82
Figure 53. Breakdown of North America Digital Biomarkers Market by End User, 2019-2030, % of Revenue 84
Figure 54. North America Addressable Market Cap in 2020-2030 by End User, Value ($ mn) and Share (%) 84
Figure 55. North America Digital Biomarkers Market: Biopharmaceutical Companies & Labs, 2019-2030, $ mn 85
Figure 56. North America Digital Biomarkers Market: Healthcare Providers, 2019-2030, $ mn 86
Figure 57. North America Digital Biomarkers Market: Insurance Payers, 2019-2030, $ mn 87
Figure 58. Breakdown of North America Digital Biomarkers Market by Country, 2019 and 2030, % of Revenue 89
Figure 59. Contribution to North America 2020-2030 Cumulative Revenue by Country, Value ($ mn) and Share (%) 90
Figure 60. U.S. Digital Biomarkers Market, 2019-2030, $ mn 92
Figure 61. Canada Digital Biomarkers Market, 2019-2030, $ mn 95
Figure 62. Digital Biomarkers Market in Mexico, 2015-2030, $ mn 97
Figure 63. Growth Stage of North America Digital Biomarkers Industry over the Forecast Period 99



List of Tables


Table 1. Snapshot of North America Digital Biomarkers Market, 2019-2030 18
Table 2. Overview of Traditional and Digital Biomarker Features, Novel Applications, and Published Examples 22
Table 3. World Smartphone Connections, Average Network Connection Speed for Smartphones and Tablets, 2019-2030 30
Table 4. World Mobile Data Traffic by Deployment Mode, 2019-2030, EB/year 31
Table 5. World Mobile Data Traffic by Device, 2019-2030, EB/year 31
Table 6. Current Challenges of Digital Biomarkers in Medical Settings 34
Table 7. Main Product Trends and Market Opportunities in North America Digital Biomarkers Market 37
Table 8. North America Digital Biomarkers Market by System Component, 2019-2030, $ mn 45
Table 9. North America Digital Biomarkers Market: Data Collection Tools by Type, 2019-2030, $ mn 48
Table 10. North America Digital Biomarkers Market by Therapeutic Area, 2019-2030, $ mn 55
Table 11. North America Digital Biomarkers Market: Neurodegenerative Disorders by Type, 2019-2030, $ mn 59
Table 12. North America Digital Biomarkers Market by Application, 2019-2030, $ mn 70
Table 13. North America Digital Biomarkers Market by Development Status, 2019-2030, $ mn 78
Table 14. North America Digital Biomarkers Market by End User, 2019-2030, $ mn 83
Table 15. North America Digital Biomarkers Market by Country, 2019-2030, $ mn 89
Table 16. U.S. Digital Biomarkers Market by System Component, 2019-2030, $ mn 93
Table 17. U.S. Digital Biomarkers Market by Therapeutic Area, 2019-2030, $ mn 93
Table 18. U.S. Digital Biomarkers Market by End User, 2019-2030, $ mn 93
Table 19. Canada Digital Biomarkers Market by System Component, 2019-2030, $ mn 96
Table 20. Canada Digital Biomarkers Market by Therapeutic Area, 2019-2030, $ mn 96
Table 21. Canada Digital Biomarkers Market by End User, 2019-2030, $ mn 96
Table 22. Mexico Digital Biomarkers Market by System Component, 2019-2030, $ mn 98
Table 23. Mexico Digital Biomarkers Market by Therapeutic Area, 2019-2030, $ mn 98
Table 24. Mexico Digital Biomarkers Market by End User, 2019-2030, $ mn 98
Table 25. Breakdown of North America Market by Key Vendor, 2019, % 101
Table 26. Actigraph LLC: Company Snapshot 104
Table 27. Actigraph LLC: Business Segmentation 104
Table 28. Actigraph LLC: Product Portfolio 105
Table 29. Actigraph LLC: Revenue, 2016-2018, $ mn 105
Table 30. Actigraph LLC: Recent Developments 105
Table 31. Risk Evaluation for Investing in North America Market, 2019-2030 134
Table 32. Critical Success Factors and Key Takeaways 137