Table of Content



List of Tables
List of Figures
Introduction
Global Markets Direct Report Coverage
Tumor Necrosis Factor Receptor Superfamily Member 16 (Low Affinity Neurotrophin Receptor p75NTR or Low Affinity Nerve Growth Factor Receptor or Gp80 LNGFR or p75 ICD or TNFRSF16 or CD271 or NGFR) - Overview
Tumor Necrosis Factor Receptor Superfamily Member 16 (Low Affinity Neurotrophin Receptor p75NTR or Low Affinity Nerve Growth Factor Receptor or Gp80 LNGFR or p75 ICD or TNFRSF16 or CD271 or NGFR) - Therapeutics Development
Products under Development by Stage of Development
Products under Development by Therapy Area
Products under Development by Indication
Products under Development by Companies
Tumor Necrosis Factor Receptor Superfamily Member 16 (Low Affinity Neurotrophin Receptor p75NTR or Low Affinity Nerve Growth Factor Receptor or Gp80 LNGFR or p75 ICD or TNFRSF16 or CD271 or NGFR) - Therapeutics Assessment
Assessment by Mechanism of Action
Assessment by Route of Administration
Assessment by Molecule Type
Tumor Necrosis Factor Receptor Superfamily Member 16 (Low Affinity Neurotrophin Receptor p75NTR or Low Affinity Nerve Growth Factor Receptor or Gp80 LNGFR or p75 ICD or TNFRSF16 or CD271 or NGFR) - Companies Involved in Therapeutics Development
Chiesi Farmaceutici SpA
Dompe Farmaceutici SpA
Levicept Ltd
PharmatrophiX Inc
Protheragen Inc
Tetraneuron SL
Tiantai Medical Technology Pty Ltd
Tumor Necrosis Factor Receptor Superfamily Member 16 (Low Affinity Neurotrophin Receptor p75NTR or Low Affinity Nerve Growth Factor Receptor or Gp80 LNGFR or p75 ICD or TNFRSF16 or CD271 or NGFR) - Drug Profiles
cenegermin - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
CHF-6467 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Drugs to Antagonize P75 Neurotrophin Receptor for Alzheimer’s Disease - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Fusion Protein to Antagonize p75NTR for Central Nervous System Disorders and Ischemic Stroke - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
LEVI-04 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
LM-11A31BHS - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Peptide to Agonize p75NTR for Neurodegenerative Diseases - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Tumor Necrosis Factor Receptor Superfamily Member 16 (Low Affinity Neurotrophin Receptor p75NTR or Low Affinity Nerve Growth Factor Receptor or Gp80 LNGFR or p75 ICD or TNFRSF16 or CD271 or NGFR) - Dormant Products
Tumor Necrosis Factor Receptor Superfamily Member 16 (Low Affinity Neurotrophin Receptor p75NTR or Low Affinity Nerve Growth Factor Receptor or Gp80 LNGFR or p75 ICD or TNFRSF16 or CD271 or NGFR) - Discontinued Products
Tumor Necrosis Factor Receptor Superfamily Member 16 (Low Affinity Neurotrophin Receptor p75NTR or Low Affinity Nerve Growth Factor Receptor or Gp80 LNGFR or p75 ICD or TNFRSF16 or CD271 or NGFR) - Product Development Milestones
Featured News & Press Releases
Jun 25, 2019: Domp? announces first patient enrollment in phase 2b clinical trial investigating novel mechanism of action in moderate to severe dry eye disease
Mar 12, 2019: Domp? receives Industry Innovation Award from the tiol Organization for Rare Disorders for the development of Oxervate eye drops (cenegermin-bkbj), for neurotrophic keratitis
Jan 03, 2019: Dompe announces first treatment with Oxervate eye drops (cenegermin-bkbj), for neurotrophic keratitis
Aug 24, 2018: Domp?’s Oxervate gets approval to treat neurotrophic keratitis in US
Jun 04, 2018: Study Finds Experimental Drug Restores some Bladder Function after Spil Cord Injury
Sep 14, 2017: Levicept Starts First-in-Human Phase I Trial of LEVI-04, A Novel Fusion Protein Therapy for Chronic Pain
Jul 20, 2017: Cenegermin Eye Drops Receive European Union Approval: The First Biotechnological Drug Resulting from Dompe Research for the Treatment of Moderate to Severe Neurotrophic Keratitis is Made in Italy
Jul 10, 2017: Dompe Farmaceutici Receives EU marketing authorisation For OXERVATE
May 23, 2017: Dompe Receives Positive CHMP Opinion in Europe For Oxervate (Cenegermin Eye Drops) For the Treatment of Adult Patients with Moderate or Severe Neurotrophic Keratitis
May 19, 2017: The European Medicines Agency: New medicine for rare eye disease
Dec 12, 2016: EMA Validates the Marketing Authorisation Application for Cenegermin Eye Drops (Oxervate) Submitted by Domp?
Dec 02, 2015: rhNGF, the Dompe Biotech Molecule for the Treatment of Neurotrophic Keratitis, Receives Orphan Drug Desigtion from the European Medicines Agency
Nov 22, 2014: Italian research at the SOI Congress: focus on therapeutic prospects of NGF, the innovative molecule developed on the basis of the studies by Rita Levi Montalcini in ophthalmology
Sep 25, 2014: EuCornea: Dompe wins the “Best Poster Award” for its prelimiry data concerning the use of rhNGF in the treatment of neurotrophic keratitis
Jul 23, 2014: Dompe announces the Food and Drug Administration has granted orphan drug desigtion to its rhNGF-based treatment for neurotrophic keratitis
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
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List of Figures



Number of Products under Development by Stage of Development, H1 2020
Number of Products under Development by Therapy Areas, H1 2020
Number of Products under Development by Top 10 Indications, H1 2020
Number of Products by Mechanism of Actions, H1 2020
Number of Products by Stage and Mechanism of Actions, H1 2020
Number of Products by Routes of Administration, H1 2020
Number of Products by Stage and Routes of Administration, H1 2020
Number of Products by Top 10 Molecule Types, H1 2020
Number of Products by Stage and Molecule Types, H1 2020


List of Tables



Number of Products under Development by Stage of Development, H1 2020
Number of Products under Development by Therapy Areas, H1 2020
Number of Products under Development by Indication, H1 2020
Number of Products under Development by Companies, H1 2020
Products under Development by Companies, H1 2020
Number of Products by Stage and Mechanism of Actions, H1 2020
Number of Products by Stage and Route of Administration, H1 2020
Number of Products by Stage and Molecule Type, H1 2020
Pipeline by Chiesi Farmaceutici SpA, H1 2020
Pipeline by Dompe Farmaceutici SpA, H1 2020
Pipeline by Levicept Ltd, H1 2020
Pipeline by PharmatrophiX Inc, H1 2020
Pipeline by Protheragen Inc, H1 2020
Pipeline by Tetraneuron SL, H1 2020
Pipeline by Tiantai Medical Technology Pty Ltd, H1 2020
Dormant Products, H1 2020
Dormant Products, H1 2020 (Contd..1), H1 2020
Discontinued Products, H1 2020