Table of Content


List of Tables
List of Figures
Introduction
Global Markets Direct Report Coverage
Serine/Threonine Protein Kise PLK1 (Polo Like Kise 1 or Serine/Threonine Protein Kise 13 or PLK1 or EC 2.7.11.21) - Overview
Serine/Threonine Protein Kise PLK1 (Polo Like Kise 1 or Serine/Threonine Protein Kise 13 or PLK1 or EC 2.7.11.21) - Therapeutics Development
Products under Development by Stage of Development
Products under Development by Therapy Area
Products under Development by Indication
Products under Development by Companies
Products under Development by Universities/Institutes
Serine/Threonine Protein Kise PLK1 (Polo Like Kise 1 or Serine/Threonine Protein Kise 13 or PLK1 or EC 2.7.11.21) - Therapeutics Assessment
Assessment by Mechanism of Action
Assessment by Route of Administration
Assessment by Molecule Type
Serine/Threonine Protein Kise PLK1 (Polo Like Kise 1 or Serine/Threonine Protein Kise 13 or PLK1 or EC 2.7.11.21) - Companies Involved in Therapeutics Development
Cyclacel Pharmaceuticals Inc
Korea United Pharm Inc
Le Sun Pharmaceuticals Ltd
Oncoheroes Biosciences Inc
Onconova Therapeutics Inc
PhoreMost Ltd
Takeda Pharmaceutical Co Ltd
Trovagene Inc
Serine/Threonine Protein Kise PLK1 (Polo Like Kise 1 or Serine/Threonine Protein Kise 13 or PLK1 or EC 2.7.11.21) - Drug Profiles
Antisense Oligonucleotide to Target MIR34 and PLK1 for Pancreatic Ductal Adenocarcinoma - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
CYC-140 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
LS-008 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
onvansertib fumarate - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
PM-001 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
rigosertib sodium - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Small Molecule to Inhibit PLK1 for Oncology - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Small Molecules to Inhibit PLK1 for Oncology - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
UN-04 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
volasertib - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Serine/Threonine Protein Kise PLK1 (Polo Like Kise 1 or Serine/Threonine Protein Kise 13 or PLK1 or EC 2.7.11.21) - Dormant Products
Serine/Threonine Protein Kise PLK1 (Polo Like Kise 1 or Serine/Threonine Protein Kise 13 or PLK1 or EC 2.7.11.21) - Discontinued Products
Serine/Threonine Protein Kise PLK1 (Polo Like Kise 1 or Serine/Threonine Protein Kise 13 or PLK1 or EC 2.7.11.21) - Product Development Milestones
Featured News & Press Releases
Dec 17, 2019: Onconova Therapeutics and Pint Pharma announce Brazilian Health Authority approval for initiating INSPIRE trial with intravenous Rigosertib in higher-risk myelodysplastic syndromes in Brazil
Dec 10, 2019: Drug combition shows promise in preclinical models of triple negative breast cancer
Dec 09, 2019: Onconova Therapeutics announces data on genomic profiles of higher risk myelodysplastic syndromes patients refractory to azacitidine therapy enrolled into the pivotal INSPIRE trial and updated oral rigosertib data informing a potential adaptive clinical trial design at the American Society of Hematology 2019 Annual Meeting
Dec 09, 2019: Efficacy, durability of response and safety of Onvansertib demonstrated in completed phase 1b trial in AML patients presented in oral session at ASH
Dec 06, 2019: Inceptua Medicines Access and Onconova Therapeutics announce pre-approval access collaboration for Rigosertib in selected countries outside the US
Dec 04, 2019: Trovagene announces data showing ability of onvansertib to rescue venetoclax-resistance in acute myeloid leukemia (AML)
Nov 14, 2019: Trovagene presents positive data in metastatic prostate cancer phase 2 trial showing clinical response in patients resistant to Zytiga
Nov 07, 2019: Onconova announces five presentations on Rigosertib in Myelodysplastic Syndromes (MDS) at the ASH 2019 Annual Meeting & Exposition
Nov 06, 2019: Trovagene announces data from acute myeloid leukemia (AML) Phase 1b/2 trial of Onvansertib chosen for oral presentation at ASH 2019 Annual Meeting
Oct 24, 2019: Onconova affirms planned completion of pivotal phase 3 INSPIRE study of Rigosertib in Myelodysplastic Syndromes by 1H20 and provides research & development update
Oct 22, 2019: Trovagene announces positive response to treatment in phase 1b/2 trial of Onvansertib in patients with KRAS-mutated metastatic colorectal cancer
Oct 10, 2019: Mission Bio awarded grant to measure minimal residual disease related to cancer relapse with single cell genomics
Oct 02, 2019: Data presented at ESMO provides ratiole for clinical trial of Onvansertib in subset of patients with highly-aggressive Triple Negative Breast Cancer (TNBC)
Oct 01, 2019: Trovagene Presents Overview of Phase 1b/2 Trial of Onvansertib in Patients with KRAS-Mutated Metastatic Colorectal Cancer (mCRC) at ESMO
Sep 30, 2019: Positive data from Trovagene phase 1b/2 study of onvansertib featured in oral presentation at European Society for Medical Oncology (ESMO) Conference
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer



List of Figures


Number of Products under Development by Stage of Development, H2 2019
Number of Products under Development by Top 10 Indications, H2 2019
Number of Products by Stage and Mechanism of Actions, H2 2019
Number of Products by Routes of Administration, H2 2019
Number of Products by Stage and Routes of Administration, H2 2019
Number of Products by Molecule Types, H2 2019
Number of Products by Stage and Molecule Types, H2 2019


List of Tables


Number of Products under Development by Stage of Development, H2 2019
Number of Products under Development by Therapy Areas, H2 2019
Number of Products under Development by Indications, H2 2019
Number of Products under Development by Indications, H2 2019 (Contd..1), H2 2019
Number of Products under Development by Companies, H2 2019
Products under Development by Companies, H2 2019
Products under Development by Companies, H2 2019 (Contd..1), H2 2019
Products under Development by Companies, H2 2019 (Contd..2), H2 2019
Number of Products under Investigation by Universities/Institutes, H2 2019
Products under Investigation by Universities/Institutes, H2 2019
Number of Products by Stage and Mechanism of Actions, H2 2019
Number of Products by Stage and Route of Administration, H2 2019
Number of Products by Stage and Molecule Type, H2 2019
Pipeline by Cyclacel Pharmaceuticals Inc, H2 2019
Pipeline by Korea United Pharm Inc, H2 2019
Pipeline by Le Sun Pharmaceuticals Ltd, H2 2019
Pipeline by Oncoheroes Biosciences Inc, H2 2019
Pipeline by Onconova Therapeutics Inc, H2 2019
Pipeline by PhoreMost Ltd, H2 2019
Pipeline by Takeda Pharmaceutical Co Ltd, H2 2019
Pipeline by Trovagene Inc, H2 2019
Dormant Products, H2 2019
Dormant Products, H2 2019 (Contd..1), H2 2019
Dormant Products, H2 2019 (Contd..2), H2 2019
Dormant Products, H2 2019 (Contd..3), H2 2019
Discontinued Products, H2 2019