Table of Content

1. Introduction To Stem Cell Therapy
1.1 Overview
1.2 Historical Development


2. Stem Cells Classification
2.1 Embryonic Stem Cells
2.2 Somatic Stem Cells
2.2.1 Mesenchymal Stem Cells
2.2.2 Neural Stem Cells
2.2.3 Hematopoietic Stem Cells
2.2.4 Endothelial Progenitor Cells (EPC)
2.2.5 Cancer Stem Cells


3. Need Of Stem Cell Therapeutics


4. Advantages of Stem Cell Therapeutics


5. Role Of Stem Cells In Cancer Treatment
5.1 Stem Cell As Suicide Gene Therapy
5.2 Stem Cell As Vehicle for Oncolytic Viruses
5.3 Stem Cells In Post Cancer Treatment
5.4 Stem Cells As Nanoparticle Carriers


6. Mechanism Of Cancer Stem Cell Targeting Drug
6.1 Targeting The Molecular Signaling Pathway
6.2 Targeting Cancer Stem Cell Markers
6.3 Targeting Cancer Stem Cell Niche & Quiescent State
6.4 Targeting The miRNA Expression
6.5 Inducing Cancer Stem Cell Apoptosis
6.6 Induction Of Cancer Stem Cell Differentiation




7. Stem Cell Transplantation In Cancer Treatment
7.1 Mechanism Of Action Of Stem Cell Transplantation

7.2 Types Of Stem Cell Transplants In Cancer Treatment
7.2.1 Autologous Stem Cell Transplantation
7.2.2 Allogeneic Stem Cell Transplantation
7.2.3 Syngeneic Stem Cell Transplantation


8. Post Therapy Cancer Stem Cell Targeting Drugs
8.1 Stem Cell Therapeutics In Skin Cancer
8.1.1 Erivedge
8.1.2 Odomzo

8.2 Stem Cell Therapeutics In Leukemia
8.2.1 Daurismo

8.3 Cancer Stem Cell Therapeutics In Colon Cancer
8.3.1 Sulindac

8.4 Cancer Stem Cell Therapeutics In Breast Cancer

8.5 Stem Cell Therapeutics In Other Cancer
8.5.1 Vorinostat
8.5.2 Belinostat
8.5.3 Romidepsine
8.5.4 Panabiostat


9. Hematopoietic Stem Cell Transplant Market
9.1 Bone Marrow Transplant Market & Cost Analysis
9.2 Cord Blood Transplant Market



10. Global Cancer Stem Cell Clinical Pipeline By Company, Indication & Phase
10.1 Research
10.2 Preclinical
10.3 Phase-I
10.4 Phase-I/II
10.5 Phase-II
10.6 Phase-III


11. Global Stem Cell Therapeutics Market Analysis
11.1 Current Market Scenario
11.2 Clinical Pipeline


12. Personalized Stem Cell Cancer Therapy
12.1 Overview
12.2 Advantages of Personalized Stem Cell Cancer Therapy


13. Personalized Stem Cell Cancer Therapy by Indication
13.1 Glioblastoma
13.1.1 Lung Cancer
13.1.2 Acute Myeloid Leukemia & Melanoma
13.1.3 Ovarian & Breast Cancer
13.1.4 Pancreatic Cancer


14. Global Stem Cell Market Dynamics Challenges & Drivers
14.1 Challenges of Cancer Stem Cell Therapeutics
14.2 Global Cancer Stem Cell Therapeutics Market Drivers


15. Global Cancer Stem Cell Therapy Market Future Outlook


16. Competitive Landscape
16.1 Aelan Cell Technologies
16.2 Baylx
16.3 Benitec Biopharma
16.4 BlueRock Therapeutics
16.5 Calidi Biotherapeutics
16.6 Cellular Dynamics International
16.7 Center for iPS Cell Research and Application
16.8 Century Therapeutics
16.9 Khloris Biosciences
16.10 ReNeuron



List of Figures


Figure 1-1: Research History on Stem Cell
Figure 2-1: Types of Stem Cells
Figure 4-1: Advantages of Stem Cell Therapies
Figure 5-1: Stem Cell Mediated Suicide Gene Therapy System
Figure 6-1 Different Molecular Signaling Pathways of Stem Cells
Figure 6-2: Mechanism of Stem Cell Therapeutics via Targeting Surface Markers
Figure 6-3: Mechanism by Inducing Cancer Stem Cell Apoptosis
Figure 6-4: Mechanism by Inducing Differentiation of Cancer Stem Cell
Figure 7-1: Mechanism of Action of Cancer Stem Cell Transplantation
Figure 7-2: Types of Stem Cell Transplantation
Figure 8-1: Erivedge - Patent on Product Type
Figure 8-2: Erivedge - Patent on Anticancer Property
Figure 8-3: Erivedge- Price for 28 Capsule Supply & Price per Unit (US$), July’2019
Figure 8-4: Odomzo Patent on Product Type
Figure 8-5: Odomzo Patent for Anticancer Property
Figure 8-6: Odomzo- Price for 30 Capsule Supply & Price per Unit (US$), July’2019
Figure 8-7: Daurismo- Price for 30 Tablets of 25mg & 100 mg Oral Tablet (US$), July’2019
Figure 8-8: Daurismo: Price per Tablet of 25 mg & 100 Mg Tablet (US$), July’2019
Figure 8-9: Sulindac: Price for 100 Tablet Supply of 150 mg & 200 mg (US$), July’2019
Figure 8-10: Sulindac: Per Unit Cost of 150 mg & 200 mg Tablet (US$), July 2019
Figure 8-11: Zolinza - Patent Issued In Different Years
Figure 8-12: Zolinza- Price for 120 Capsule Supplies Of 100mg & Price per Unit (US$), July’2019
Figure 813: Beleodaq - Patent Issued & Expiration Year for First Patent
Figure 8-14: Beleodaq - Patent Issued & Expiration Year for Second Patent
Figure 8-15: Istodax: Patent Issued & Expiration Year
Figure 9-1: Cost of Different Bone Marrow Transplant (US$ Million), July’2019
Figure 9-2: Bone Marrow Transplant Market (US$ Billion), 2018 - 2025
Figure 9-3: Global - Autologous v/s Allogeneic Bone Marrow Transplant Market(%), 2019
Figure 9-4: Global - Cord Blood Transplant Market (US$ Million), 2018-2025
Figure 11-1: Global - Cancer Stem Cell Therapeutics Market Opportunity (US$ Billion), 2019 - 2025
Figure 11-2: Global - Cancer Stem Cell Therapy Clinical Pipeline (%), 2019 till 2025
Figure 11-3: Global - Cancer Stem Cell Therapy Clinical Pipeline (Number of Trials), 2019 till 2025
Figure 11-4: Global - Cancer Stem Cell Therapy Clinical Pipeline by Country (Number of Trials), 2019 till 2025
Figure 11-5: Global - Cancer Stem Cell Therapy Clinical Pipeline by Company (Number of Trials), 2019 till 2025
Figure 12-1: Steps of Personalised Stem Cell Cancer Therapy
Figure 14-1: Challenges of Cancer Stem Cell Therapeutics
Figure 14-2: Drivers of Cancer Stem Cell Therapeutics
Figure 16-1: Baylx - Clinical Pipeline
Figure 16-2: Benitec Bioparma - Clinical Pipeline
Figure 16-3: BlueRock Therapeutics - Clinical Pipeline
Figure 16-4: Calidi Biotherapeutics - Clinical Pipeline