Table of Content


Chapter 1 The Emergence of Cell Therapy Using TILs
Introduction
Analyst’s Credentials
Related Reports
Chapter 2 Development of TIL Therapies in Metastic Melanoma
TIL Generation Explained
Importance of Lymphodepletion
Role of Interleukin-2
Feasibility of TIL as a Mainstream Treatment Option
Chapter 3 Development of TIL Therapies in Other Tumour Types
Cervical Cancer
Ovarian Cancer
Kidney Cancer
Gastrointestinal Cancer
Head and Neck Cancers
Chapter 4 Clinical Development of TIL Therapies
Lifileucel (LN-144), Iovance Biotherapeutics
LN-145, Iovance Biotherapeutics
TILT-123, TILT Biotherapeutics
Optera Therapeutics Corp.
Other Centers Conducting TIL Research
Future Perspectives for TIL
Chapter 5 References



List of Figures



Figure 1 : Generation of Tumor Infiltrating Lymphocytes
Figure 2 : IL-2 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types
Figure 3 : TILT Biotherapeutics Development Pipeline

 

List of Tables



Table 1 : TILs and Tumor Specific Antigens
Table 2 : Adoptive T-Cell Therapy (ATC) Cellular Therapies
Table 3 : Clinical Trials Studying TIL Therapies