Table of Content

1 INTRODUCTION 14
1.1 OBJECTIVES OF THE STUDY 14
1.2 MARKET DEFINITION 14
1.3 MARKET SCOPE 15
1.3.1 MARKETS COVERED 15
1.3.2 YEARS CONSIDERED FOR THE STUDY 15
1.4 CURRENCY 16
1.5 LIMITATIONS 16
1.6 STAKEHOLDERS 16

2 RESEARCH METHODOLOGY 17
2.1 RESEARCH DATA 17
2.1.1 SECONDARY SOURCES 18
2.1.2 KEY DATA FROM SECONDARY SOURCES 18
2.1.3 PRIMARY SOURCES 19
2.1.3.1 Key industry insights 19
2.1.3.2 key data from primary sources 20
2.2 MARKET SIZE ESTIMATION 20
2.3 MARKET BREAKDOWN AND DATA TRIANGULATION 22

3 EXECUTIVE SUMMARY 23

4 PREMIUM INSIGHTS 27
4.1 PROTEIN STABILITY ANALYSIS: MARKET OVERVIEW 27
4.2 NORTH AMERICA: PROTEIN STABILITY ANALYSIS MARKET, BY PRODUCT (2018) 28
4.3 REGIONAL SPLIT: PROTEIN STABILITY ANALYSIS MARKET, BY COUNTRY (2018) 29

5 MARKET OVERVIEW 30
5.1 INTRODUCTION 30
5.2 MARKET DYNAMICS 30
5.2.1 DRIVERS 31
5.2.1.1 Growing adoption of open innovation models in pharmaceutical and biotechnology companies 31
5.2.1.2 Increasing pharmaceutical outsourcing 31
5.2.2 RESTRAINTS 32
5.2.2.1 High cost of protein stability analysis instruments 32
5.2.3 OPPORTUNITIES 32
5.2.3.1 Emerging markets 32
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5.2.4 CHALLENGES 32
5.2.4.1 Shortage of skilled professionals 32

6 PROTEIN STABILITY ANALYSIS MARKET, BY PRODUCT 33
6.1 INTRODUCTION 34
6.2 REAGENTS AND ASSAY KITS 34
6.2.1 REAGENTS AND ASSAY KITS PLAY A MAJOR ROLE IN PROTEIN STABILITY ANALYSIS AND HOLD THE LARGEST MARKET SHARE 34
6.3 INSTRUMENTS 36
6.3.1 DEMAND FOR HIGH-THROUGHPUT SYSTEMS IS INCREASING IN LABORATORIES 36
6.4 CONSUMABLES AND ACCESSORIES 37
6.4.1 DEVELOPMENT OF HIGH-QUALITY CONSUMABLES AND ACCESSORIES IS DRIVING MARKET GROWTH 37
6.5 SOFTWARE 38
6.5.1 ADVANCEMENTS IN SOFTWARE LIKELY TO DRIVE MARKET 38

7 PROTEIN STABILITY ANALYSIS MARKET, BY TECHNIQUE 40
7.1 INTRODUCTION 41
7.2 CHROMATOGRAPHY 41
7.2.1 HIGH USAGE OF HPLC AND SIZE-EXCLUSION CHROMATOGRAPHY FOR PROTEIN STABILITY AND AGGREGATE ANALYSIS TO DRIVE THE GROWTH OF THIS SEGMENT 41
7.3 SPECTROSCOPY 43
7.3.1 ADVANTAGES OF SPECTROSCOPIC METHODS TO DRIVE THEIR DEMAND IN PROTEIN STABILITY ANALYSIS 43
7.3.1.1 Mass spectrometry 44
7.3.1.2 Dynamic light scattering 44
7.3.1.3 Circular dichroism 44
7.3.1.4 Other spectrometry techniques 45
7.4 SURFACE PLASMON RESONANCE 45
7.4.1 SPR IS USED FOR GETTING KEY INSIGHTS INTO BIOLOGICAL PROCESSES AND MOLECULAR BINDING MECHANISMS 45
7.5 DIFFERENTIAL SCANNING CALORIMETRY 46
7.5.1 DSC IS WIDELY USED IN DRUG DISCOVERY AND DEVELOPMENT FOR THE CHARACTERIZATION OF PROTEINS 46
7.6 DIFFERENTIAL SCANNING FLUORIMETRY 47
7.6.1 DSC IS A RAPID AND INEXPENSIVE SCREENING METHOD TO IDENTIFY LOW-MOLECULAR-WEIGHT LIGANDS THAT BIND AND STABILIZE PURIFIED PROTEINS 47
7.7 OTHER TECHNIQUES 48
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8 PROTEIN STABILITY ANALYSIS MARKET, BY END USER 50
8.1 INTRODUCTION 51
8.2 PHARMACEUTICAL & BIOTECHNOLOGY COMPANIES 51
8.2.1 PHARMACEUTICAL & BIOTECHNOLOGY COMPANIES ARE THE LARGEST END USERS OF PROTEIN STABILITY ANALYSIS 51
8.3 CONTRACT RESEARCH ORGANIZATIONS 53
8.3.1 OUTSOURCING OF ANALYTICAL AND CLINICAL SERVICES HELPS PHARMA & BIOPHARMA COMPANIES TO MITIGATE RISK?A MAJOR DRIVER FOR CONTRACT RESEARCH ORGANIZATIONS 53
8.4 ACADEMIC & GOVERNMENT INSTITUTES 54
8.4.1 GOVERNMENT SUPPORT IN THE FORM OF FUNDING AND RISING NUMBER OF INDUSTRY-ACADEMIA COLLABORATIONS DRIVES MARKET GROWTH IN THIS END-USER SEGMENT 54

9 PROTEIN STABILITY ANALYSIS MARKET, BY REGION 56
9.1 INTRODUCTION 57
9.2 NORTH AMERICA 58
9.2.1 US 61
9.2.1.1 Growing R&D investments in the US to drive market growth 61
9.2.2 CANADA 63
9.2.2.1 Increasing government fund for research activities will drive market growth 63
9.3 EUROPE 65
9.3.1 GERMANY 68
9.3.1.1 Germany holds the largest share of the European protein stability analysis market 68
9.3.2 FRANCE 70
9.3.2.1 Availability of funds for research from government and private organizations is driving the growth of this market 70
9.3.3 UK 72
9.3.3.1 Over one-third of the UK’s medical biotech sector is engaged in drug discovery & development 72
9.3.4 REST OF EUROPE 73
9.4 ASIA PACIFIC 75
9.4.1 HIGH FOCUS ON HEALTHCARE MODERNIZATION WILL CREATE GROWTH OPPORTUNITIES 75
9.5 REST OF THE WORLD 77
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10 COMPETITIVE LANDSCAPE 79
10.1 INTRODUCTION 79
10.2 MARKET RANKING ANALYSIS, 2018 79
10.3 COMPETITIVE LEADERSHIP MAPPING 80
10.3.1 VISIONARY LEADERS 80
10.3.2 INNOVATORS 80
10.3.3 DYNAMIC DIFFERENTIATORS 80
10.3.4 EMERGING PLAYERS 80
10.4 COMPETITIVE SITUATION AND TRENDS 82
10.4.1 PRODUCT LAUNCHES 82
10.4.2 COLLABORATIONS, PARTNERSHIPS, AND AGREEMENTS 82
10.4.3 EXPANSION 83
10.4.4 ACQUISITION 83

11 COMPANY PROFILES 84
(Business Overview, Products Offered, Recent Developments, MnM View)*
11.1 THERMO FISHER SCIENTIFIC 84
11.2 AGILENT TECHNOLOGIES, INC. 87
11.3 PERKINELMER, INC. 89
11.4 WATERS CORPORATION 91
11.5 SHIMADZU CORPORATION 94
11.6 GENERAL ELECTRIC 96
11.7 HORIBA, LTD 98
11.8 SPECTRIS PLC 100
11.9 ENZO BIOCHEM, INC. 102
11.10 SETARAM INSTRUMENTATION 103
11.11 UNCHAINED LABS 104
*Business Overview, Products Offered, Recent Developments, MnM View might not be captured in case of unlisted companies.

12 APPENDIX 105
12.1 DISCUSSION GUIDE 105
12.2 KNOWLEDGE STORE: MARKETSANDMARKETS’ SUBSCRIPTION PORTAL 108
12.3 AVAILABLE CUSTOMIZATIONS 110
12.4 RELATED REPORTS 110
12.5 AUTHOR DETAILS 111



List of Figures



FIGURE 1 RESEARCH DESIGN 17
FIGURE 2 PRIMARY SOURCES 19
FIGURE 3 PROTEIN STABILITY ANALYSIS MARKET: TOP-DOWN APPROACH 21
FIGURE 4 PROTEIN STABILITY ANALYSIS MARKET: BOTTOM-UP APPROACH 21
FIGURE 5 DATA TRIANGULATION METHODOLOGY 22
FIGURE 6 PROTEIN STABILITY ANALYSIS MARKET, BY PRODUCT 2018 VS. 2024 (USD MILLION) 23
FIGURE 7 PROTEIN STABILITY ANALYSIS MARKET SHARE, BY TECHNIQUE, 2018. 24
FIGURE 8 PROTEIN STABILITY ANALYSIS MARKET SHARE, BY END USER, 2018 VS. 2024 25
FIGURE 9 GEOGRAPHICAL SNAPSHOT OF THE PROTEIN STABILITY ANALYSIS MARKET 26
FIGURE 10 GROWING ADOPTION OF OPEN INNOVATION MODELS IN PHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES IS DRIVING THE MARKET 27
FIGURE 11 REAGENTS AND ASSAY KITS SEGMENT HELD THE LARGEST SHARE OF THE PROTEIN STABILITY ANALYSIS MARKET IN NORTH AMERICA 28
FIGURE 12 US DOMINATED THE PROTEIN STABILITY ANALYSIS MARKET IN 2018 29
FIGURE 13 PROTEIN STABILITY ANALYSIS MARKET: DRIVERS, RESTRAINTS, OPPORTUNITIES, AND CHALLENGES 30
FIGURE 14 NORTH AMERICA: PROTEIN STABILITY ANALYSIS MARKET SNAPSHOT 58
FIGURE 15 EUROPE: PROTEIN STABILITY ANALYSIS MARKET SNAPSHOT 65
FIGURE 16 COMPETITIVE LEADERSHIP MAPPING OF THE PROTEIN STABILITY
ANALYSIS MARKET 81
FIGURE 17 THERMO FISHER SCIENTIFIC: COMPANY SNAPSHOT (2018) 84
FIGURE 18 AGILENT TECHNOLOGIES, INC.: COMPANY SNAPSHOT (2018) 87
FIGURE 19 PERKINELMER, INC.: COMPANY SNAPSHOT (2018) 89
FIGURE 20 WATERS CORPORATION: COMPANY SNAPSHOT (2018) 91
FIGURE 21 SHIMADZU CORPORATION: COMPANY SNAPSHOT (2018) 94
FIGURE 22 GENERAL ELECTRIC: COMPANY SNAPSHOT (2018) 96
FIGURE 23 HORIBA, LTD: COMPANY SNAPSHOT (2017) 98
FIGURE 24 SPECTRIS PLC: COMPANY SNAPSHOT (2018) 100
FIGURE 25 ENZO BIOCHEM, INC.: COMPANY SNAPSHOT (2018) 102

 

List of Tables



TABLE 1 PROTEIN STABILITY ANALYSIS MARKET, BY PRODUCT, 2016–2024 (USD MILLION) 34
TABLE 2 PROTEIN STABILITY ANALYSIS MARKET FOR REAGENTS AND ASSAY KITS BY REGION, 2016–2024 (USD MILLION) 35
TABLE 3 NORTH AMERICA: PROTEIN STABILITY ANALYSIS MARKET FOR REAGENTS AND ASSAY KITS, BY COUNTRY, 2016–2024 (USD MILLION) 35
TABLE 4 PROTEIN STABILITY ANALYSIS MARKET FOR INSTRUMENTS, BY REGION 2016–2024 (USD MILLION) 36
TABLE 5 NORTH AMERICA: PROTEIN STABILITY ANALYSIS MARKET FOR INSTRUMENT BY COUNTRY, 2016–2024 (USD MILLION) 37
TABLE 6 PROTEIN STABILITY ANALYSIS MARKET FOR CONSUMABLES AND ACCESSORIES, BY REGION, 2016–2024 (USD MILLION) 37
TABLE 7 NORTH AMERICA: PROTEIN STABILITY ANALYSIS MARKET FOR CONSUMABLES AND ACCESSORIES, BY COUNTRY, 2016–2024 (USD MILLION) 38
TABLE 8 PROTEIN STABILITY ANALYSIS MARKET FOR SOFTWARE, BY REGION 2016–2024 (USD MILLION) 38
TABLE 9 NORTH AMERICA: PROTEIN STABILITY ANALYSIS MARKET FOR SOFTWARE COMPANIES, BY COUNTRY, 2016–2024 (USD MILLION) 39
TABLE 10 PROTEIN STABILITY ANALYSIS MARKET, BY TECHNIQUE 2016–2024 (USD MILLION) 41
TABLE 11 PROTEIN STABILITY ANALYSIS MARKET FOR CHROMATOGRAPHY, BY REGION, 2016–2024 (USD MILLION) 42
TABLE 12 NORTH AMERICA: PROTEIN STABILITY ANALYSIS MARKET FOR CHROMATOGRAPHY, BY COUNTRY, 2016–2024 (USD MILLION) 42
TABLE 13 PROTEIN STABILITY ANALYSIS MARKET FOR SPECTROMETRY, BY TYPE 2016–2024 (USD MILLION) 43
TABLE 14 PROTEIN STABILITY ANALYSIS MARKET FOR SPECTROMETRY, BY REGION 2016–2024 (USD MILLION) 43
TABLE 15 NORTH AMERICA: PROTEIN STABILITY ANALYSIS MARKET FOR SPECTROMETRY BY COUNTRY, 2016–2024 (USD MILLION) 44
TABLE 16 PROTEIN STABILITY ANALYSIS MARKET FOR SURFACE PLASMON RESONANCE BY REGION, 2016–2024 (USD MILLION) 45
TABLE 17 NORTH AMERICA: PROTEIN STABILITY ANALYSIS MARKET FOR SURFACE PLASMON RESONANCE, BY COUNTRY, 2016–2024 (USD MILLION) 46
TABLE 18 PROTEIN STABILITY ANALYSIS MARKET FOR DIFFERENTIAL SCANNING CALORIMETRY, BY REGION, 2016–2024 (USD MILLION) 46
TABLE 19 NORTH AMERICA: PROTEIN STABILITY ANALYSIS MARKET FOR DIFFERENTIAL SCANNING CALORIMETRY, BY COUNTRY, 2016–2024 (USD MILLION) 47
TABLE 20 PROTEIN STABILITY ANALYSIS MARKET FOR DIFFERENTIAL SCANNING FLUORIMETRY, BY REGION, 2016–2024 (USD MILLION) 47
TABLE 21 NORTH AMERICA: PROTEIN STABILITY ANALYSIS MARKET FOR DIFFERENTIAL SCANNING FLUORIMETRY, BY COUNTRY, 2016–2024 (USD MILLION) 48
TABLE 22 PROTEIN STABILITY ANALYSIS MARKET FOR OTHER TECHNIQUES, BY REGION, 2016–2024 (USD MILLION) 48
TABLE 23 NORTH AMERICA: PROTEIN STABILITY ANALYSIS MARKET FOR OTHER TECHNIQUES, BY COUNTRY, 2016–2024 (USD MILLION) 49
TABLE 24 PROTEIN STABILITY ANALYSIS MARKET, BY END USER, 2016–2024 (USD MILLION) 51
TABLE 25 PROTEIN STABILITY ANALYSIS MARKET FOR PHARMACEUTICAL & BIOTECHNOLOGY COMPANIES, BY REGION, 2016–2024 (USD MILLION) 52
TABLE 26 NORTH AMERICA: PROTEIN STABILITY ANALYSIS MARKET FOR PHARMACEUTICAL & BIOTECHNOLOGY COMPANIES, BY COUNTRY, 2016–2024 (USD MILLION) 52
TABLE 27 PROTEIN STABILITY ANALYSIS MARKET FOR CONTRACT RESEARCH ORGANIZATIONS, BY REGION, 2016–2024 (USD MILLION) 53
TABLE 28 NORTH AMERICA: PROTEIN STABILITY ANALYSIS MARKET FOR CONTRACT RESEARCH ORGANIZATIONS, BY COUNTRY, 2016–2024 (USD MILLION) 54
TABLE 29 PROTEIN STABILITY ANALYSIS MARKET FOR ACADEMIC & GOVERNMENT INSTITUTES, BY REGION, 2016–2024 (USD MILLION) 55
TABLE 30 NORTH AMERICA: PROTEIN STABILITY ANALYSIS MARKET FOR ACADEMIC & GOVERNMENT INSTITUTES, BY COUNTRY, 2016–2024 (USD MILLION) 55
TABLE 31 PROTEIN STABILITY ANALYSIS MARKET, BY REGION, 2016–2024 (USD MILLION) 57
TABLE 32 NORTH AMERICA: PROTEIN STABILITY ANALYSIS MARKET, BY COUNTRY 2016–2024 (USD MILLION) 59
TABLE 33 NORTH AMERICA: PROTEIN STABILITY ANALYSIS MARKET, BY PRODUCT 2016–2024 (USD MILLION) 59
TABLE 34 NORTH AMERICA: PROTEIN STABILITY ANALYSIS MARKET, BY TECHNIQUE 2016–2024 (USD MILLION) 60
TABLE 35 NORTH AMERICA: PROTEIN STABILITY ANALYSIS MARKET, BY END USER 2016–2024 (USD MILLION) 60
TABLE 36 US: PROTEIN STABILITY ANALYSIS MARKET, BY PRODUCT 2016–2024 (USD MILLION) 61
TABLE 37 US: PROTEIN STABILITY ANALYSIS MARKET, BY TECHNIQUE 2016–2024 (USD MILLION) 62
TABLE 38 US: PROTEIN STABILITY ANALYSIS MARKET, BY END USER 2016–2024 (USD MILLION) 62
TABLE 39 CANADA: PROTEIN STABILITY ANALYSIS MARKET, BY PRODUCT 2016–2024 (USD MILLION) 63
TABLE 40 CANADA: PROTEIN STABILITY ANALYSIS MARKET, BY TECHNIQUE 2016–2024 (USD MILLION) 64
TABLE 41 CANADA: PROTEIN STABILITY ANALYSIS MARKET, BY END USER 2016–2024 (USD MILLION) 64
TABLE 42 EUROPE: PROTEIN STABILITY ANALYSIS MARKET, BY COUNTRY/REGION 2016–2024 (USD MILLION) 66
TABLE 43 EUROPE: PROTEIN STABILITY ANALYSIS MARKET, BY PRODUCT 2016–2024 (USD MILLION) 66
TABLE 44 EUROPE: PROTEIN STABILITY ANALYSIS MARKET, BY TECHNIQUE 2016–2024 (USD MILLION) 67
TABLE 45 EUROPE: PROTEIN STABILITY ANALYSIS MARKET, BY END USER 2016–2024 (USD MILLION) 67
TABLE 46 GERMANY: PROTEIN STABILITY ANALYSIS MARKET, BY PRODUCT 2016–2024 (USD MILLION) 68
TABLE 47 GERMANY: PROTEIN STABILITY ANALYSIS MARKET, BY TECHNIQUE 2016–2024 (USD MILLION) 69
TABLE 48 GERMANY: PROTEIN STABILITY ANALYSIS MARKET, BY END USER 2016–2024 (USD MILLION) 69
TABLE 49 FRANCE: PROTEIN STABILITY ANALYSIS MARKET, BY PRODUCT 2016–2024 (USD MILLION) 70
TABLE 50 FRANCE: PROTEIN STABILITY ANALYSIS MARKET, BY TECHNIQUE 2016–2024 (USD MILLION) 71
TABLE 51 FRANCE: PROTEIN STABILITY ANALYSIS MARKET, BY END USER 2016–2024 (USD MILLION) 71
TABLE 52 UK: PROTEIN STABILITY ANALYSIS MARKET, BY PRODUCT 2016–2024 (USD MILLION) 72
TABLE 53 UK: PROTEIN STABILITY ANALYSIS MARKET, BY TECHNIQUE 2016–2024 (USD MILLION) 72
TABLE 54 UK: PROTEIN STABILITY ANALYSIS MARKET, BY END USER 2016–2024 (USD MILLION) 73
TABLE 55 ROE: PROTEIN STABILITY ANALYSIS MARKET, BY PRODUCT 2016–2024 (USD MILLION) 73
TABLE 56 ROE: PROTEIN STABILITY ANALYSIS MARKET, BY TECHNIQUE 2016–2024 (USD MILLION) 74
TABLE 57 ROE: PROTEIN STABILITY ANALYSIS MARKET, BY END USER 2016–2024 (USD MILLION) 74
TABLE 58 APAC: PROTEIN STABILITY ANALYSIS MARKET, BY PRODUCT 2016–2024 (USD MILLION) 75
TABLE 59 APAC: PROTEIN STABILITY ANALYSIS MARKET, BY TECHNIQUE 2016–2024 (USD MILLION) 76
TABLE 60 APAC: PROTEIN STABILITY ANALYSIS MARKET, BY END USER 2016–2024 (USD MILLION) 76
TABLE 61 ROW: PROTEIN STABILITY ANALYSIS MARKET, BY PRODUCT 2016–2024 (USD MILLION) 77
TABLE 62 ROW: PROTEIN STABILITY ANALYSIS MARKET, BY TECHNIQUE 2016–2024 (USD MILLION) 78
TABLE 63 ROW: PROTEIN STABILITY ANALYSIS MARKET, BY END USER 2016–2024 (USD MILLION) 78
TABLE 64 PROTEIN STABILITY ANALYSIS MARKET RANKING, BY KEY PLAYER (2018) 79
TABLE 65 PRODUCT LAUNCHES, 2016–2019 82
TABLE 66 COLLABORATIONS/PARTNERSHIPS/AGREEMENTS, 2016–2019 82
TABLE 67 EXPANSION, 2016–2019 83
TABLE 68 ACQUISITION, 2016–2019 83