Table of Content

1 INTRODUCTION 15
1.1 OBJECTIVES OF THE STUDY 15
1.2 MARKET DEFINITION 15
1.3 MARKET SCOPE 16
1.3.1 MARKETS COVERED 16
1.3.2 YEARS CONSIDERED FOR THE STUDY 16
1.4 CURRENCY USED FOR THE STUDY 17
1.5 MAJOR MARKET STAKEHOLDERS 17

2 RESEARCH METHODOLOGY 18
2.1 RESEARCH DATA 18
2.1.1 SECONDARY DATA 19
2.1.1.1 Major secondary sources referred 20
2.1.2 PRIMARY DATA 21
2.2 MARKET ESTIMATION METHODOLOGY 21
2.2.1 PROCEDURE-BASED MARKET ESTIMATION 23
2.2.2 REVENUE MAPPING-BASED MARKET ESTIMATION 23
2.2.3 PRIMARY RESEARCH VALIDATION 24
2.3 DATA TRIANGULATION 25
2.4 RESEARCH ASSUMPTIONS 26
2.5 RESEARCH LIMITATIONS 26

3 EXECUTIVE SUMMARY 27

4 PREMIUM INSIGHTS 31
4.1 LIVE CELL ENCAPSULATION MARKET OVERVIEW 31
4.2 EUROPE: LIVE CELL ENCAPSULATION MARKET, BY POLYMER TYPE 32
4.3 GLOBAL LIVE CELL ENCAPSULATION MARKET, BY TECHNIQUE 33
4.4 LIVE CELL ENCAPSULATION MARKET, BY APPLICATION 34
4.5 LIVE CELL ENCAPSULATION MARKET, BY COUNTRY 35

5 MARKET OVERVIEW 36
5.1 INTRODUCTION 36
5.2 MARKET DYNAMICS 36
5.2.1 DRIVERS 37
5.2.1.1 Increasing incidence of target diseases 37
5.2.1.2 Focus on novel drug delivery systems for disease treatment 37
5.2.1.3 Technology Advancements 37
5.2.1.4 Increasing public-private investments to support novel product development 38
5.2.1.5 Rising public awareness related to the clinical role of encapsulated cells in disease management 38
5.2.2 RESTRAINTS 39
5.2.2.1 High product manufacturing costs 39
5.2.2.2 Limited market availability of high-quality raw materials 39
5.2.3 OPPORTUNITIES 39
5.2.3.1 Rising research activity 39
5.2.4 CHALLENGES 40
5.2.4.1 Adoption of alternative therapies 40

6 LIVE CELL ENCAPSULATION MARKET, BY MANUFACTURING TECHNIQUES 41
6.1 INTRODUCTION 42
6.2 SIMPLE DRIPPING 43
6.2.1 GLOBAL LIVE CELL ENCAPSULATION MARKET SPLIT FOR SIMPLE DRIPPING TECHNIQUE, BY APPLICATION 44
6.3 ELECTROSTATIC DRIPPING 45
6.3.1 GLOBAL LIVE CELL ENCAPSULATION MARKET SPLIT FOR ELECTROSTATIC DRIPPING TECHNIQUE, BY APPLICATION 46
6.4 COAXIAL AIRFLOW 46
6.4.1 GLOBAL LIVE CELL ENCAPSULATION MARKET SPLIT FOR COAXIAL AIRFLOW TECHNIQUE, BY APPLICATION 47
6.5 LIQUID-JET BREAK-UP 48
6.5.1 GLOBAL LIVE CELL ENCAPSULATION MARKET SPLIT FOR LIQUID JET BREAK UP TECHNIQUE, BY APPLICATION 48
6.6 VIBRATING-JET TECHNIQUE 49
6.6.1 GLOBAL LIVE CELL ENCAPSULATION MARKET SPLIT FOR VIBRATING JET TECHNIQUE, BY APPLICATION 50
6.7 JET CUTTING 50
6.7.1 GLOBAL LIVE CELL ENCAPSULATION MARKET SPLIT FOR JET CUTTING TECHNIQUE, BY APPLICATION 51
6.8 ROTATING DISK ATOMIZATION 52
6.8.1 GLOBAL LIVE CELL ENCAPSULATION MARKET SPLIT FOR ROTATING DISK ATOMIZATION TECHNIQUE, BY APPLICATION 53

7 LIVE CELL ENCAPSULATION MARKET, BY POLYMER TYPE 54
7.1 INTRODUCTION 55
7.2 ALGINATE 57
7.2.1 ALGINATE IS THE MOST WIDELY ADOPTED MATERIAL FOR THE ENCAPSULATION OF LIVING CELLS 57
7.3 HEMA-MMA 58
7.3.1 HEMA-MMA-BASED PRODUCTS ARE USED MAINLY FOR LIVER TRANSPLANTATION PROCEDURES AND DIABETES MANAGEMENT 58
?
7.4 CHITOSAN 59
7.4.1 INADEQUATE AVAILABILITY OF NATURAL CHITOSAN SOURCES IS EXPECTED TO HAMPER MARKET GROWTH 59
7.5 SILICEOUS ENCAPSULATES 60
7.5.1 PROCEDURAL BENEFITS OFFERED BY SILICEOUS ENCAPSULATES SUCH AS EFFECTIVE PROCESS CONTROL & HIGH PROCESS ADJUSTABILITY TO DRIVE MARKET GROWTH 60
7.6 CELLULOSE SULFATE 61
7.6.1 TECHNO-COMMERCIAL BENEFITS SUCH AS HIGH MECHANICAL STABILITY & ADJUSTABILITY TO DRIVE MARKET GROWTH 61
7.7 PAN-PVC 62
7.7.1 PAN-PVC POLYMERS HAVE MECHANICAL STABILITY, PERMEABILITY, AND HIGH BIOCOMPATIBILITY 62
7.8 OTHER POLYMERS 63

8 LIVE CELL ENCAPSULATION MARKET, BY APPLICATION 64
8.1 INTRODUCTION 65
8.2 DRUG DELIVERY 66
8.2.1 DRUG DELIVERY FORMS THE LARGEST APPLICATION SEGMENT OF THE LIVE CELL ENCAPSULATION MARKET 66
8.3 REGENERATIVE MEDICINE 67
8.3.1 CLINICAL RISK OF CLOGGING IN THE HEPATIC VASCULAR SYSTEM IS EXPECTED TO HAMPER THE ADOPTION OF CELL ENCAPSULATION FOR REGENERATIVE MEDICINE 67
8.4 CELL TRANSPLANTATION 68
8.4.1 INCREASING INCIDENCE OF TARGET DISEASES & TECHNOLOGICAL ADVANCEMENTS IN THE FIELD OF CELL TRANSPLANTATION TO SUPPORT MARKET GROWTH 68
8.5 PROBIOTICS 69
8.5.1 PROBIOTICS APPLICATIONS TO REGISTER THE HIGHEST GROWTH DURING THE FORECAST PERIOD 69
8.6 RESEARCH 70
8.6.1 GROWING AWARENESS ABOUT THE RESEARCH APPLICATIONS OF CELL ENCAPSULATION TECHNIQUES AND THE INCREASING AVAILABILITY OF PUBLIC-PRIVATE FUNDING, INVESTMENTS, & GRANTS TO DRIVE MARKET GROWTH 70

9 LIVE CELL ENCAPSULATION MARKET, BY REGION 72
9.1 INTRODUCTION 73
9.2 NORTH AMERICA 74
9.2.1 US 78
9.2.1.1 US accounted for the largest share of the global live cell encapsulation market in 2018; this trend to continue during the forecast period 78
9.2.2 CANADA 79
9.2.2.1 Growth in the live cell encapsulation market in Canada is driven by the growing research activities related to cell encapsulation 79
9.3 EUROPE 80
9.3.1 GERMANY 84
9.3.1.1 Germany to witness the highest growth in the European live cell encapsulation market during the forecast period 84
9.3.2 UK 85
9.3.2.1 Growth in this market is driven by the increasing number of awareness activities related to the technological advancements and efficiency of cell encapsulation techniques 85
9.3.3 FRANCE 86
9.3.3.1 Increasing prevalence of chronic diseases to drive market growth 86
9.3.4 REST OF EUROPE 86
9.4 ASIA PACIFIC 88
9.4.1 JAPAN 92
9.4.1.1 Japan to register the highest growth in the Asia Pacific live cell encapsulation market 92
9.4.2 CHINA 93
9.4.2.1 Supportive government regulations for the expansion and modernization of healthcare facilities are driving market growth 93
9.4.3 INDIA 94
9.4.3.1 Increasing prevalence of target chronic diseases to support market growth 94
9.4.4 REST OF ASIA PACIFIC 95
9.5 LATIN AMERICA 96
9.6 MIDDLE EAST & AFRICA 99

10 COMPETITIVE LANDSCAPE 102
10.1 OVERVIEW 102
10.2 GLOBAL MARKET SHARE ANALYSIS (2017) 103
10.3 COMPETITIVE SCENARIO (2015 TO 2019) 104
10.4 COMPETITIVE LEADERSHIP MAPPING 106
10.4.1 VENDOR INCLUSION CRITERIA 106
10.4.1.1 Visionary Leaders 106
10.4.1.2 Innovators 106
10.4.1.3 Dynamic Differentiators 107
10.4.1.4 Emerging Companies 107
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11 COMPANY PROFILES 108
(Business Overview, Products Offered, Recent Developments, MnM View)*
11.1 INTRODUCTION 108
11.2 BALCHEM CORPORATION 108
11.3 BIOTIME, INC. 110
11.4 BLACKTRACE GROUP 112
11.5 B?CHI LABORTECHNIK AG 114
11.6 ENCAPSYS, LLC 115
11.7 EVONIK INDUSTRIES 116
11.8 LIVING CELL TECHNOLOGIES 118
11.9 LYCORED 119
11.10 MERCK KGAA 120
11.11 MIKROCAPS 123
11.12 NEUROTECH HOLDINGS, LLC. 124
11.13 REED PACIFIC PTY LIMITED 125
11.14 SERNOVA CORPORATION 127
11.15 SIGILON THERAPEUTICS 128
11.16 VIACYTE, INC. 129
*Business Overview, Products Offered, Recent Developments, MnM View might not be captured in case of unlisted companies.
12 APPENDIX 130
12.1 DISCUSSION GUIDE 130
12.2 KNOWLEDGE STORE: MARKETSANDMARKETS? SUBSCRIPTION PORTAL 134
12.3 AVAILABLE CUSTOMIZATIONS 136
12.4 RELATED REPORTS 137
12.5 AUTHOR DETAILS 138



List of Figures



FIGURE 1 RESEARCH DESIGN 18
FIGURE 2 BREAKDOWN OF PRIMARIES: LIVE CELL ENCAPSULATION MARKET 21
FIGURE 3 RESEARCH METHODOLOGY: HYPOTHESIS BUILDING 22
FIGURE 4 MARKET SIZE ESTIMATION: LIVE CELL ENCAPSULATION MARKET 24
FIGURE 5 DATA TRIANGULATION METHODOLOGY 25
FIGURE 6 LIVE CELL ENCAPSULATION MARKET, BY TECHNIQUE, 2018 VS. 2024 27
FIGURE 7 LIVE CELL ENCAPSULATION MARKET, BY POLYMER TYPE 2018 VS. 2024 (USD MILLION) 28
FIGURE 8 LIVE CELL ENCAPSULATION MARKET SHARE, BY APPLICATION, 2018 VS. 2024 29
FIGURE 9 GEOGRAPHIC SNAPSHOT: LIVE CELL ENCAPSULATION MARKET 30
FIGURE 10 RISING RESEARCH ACTIVITY AND FOCUS ON NOVEL DRUG DELIVERY SYSTEMS FOR DISEASE TREATMENT WILL DRIVE DEMAND FOR LIVE CELL ENCAPSULATION 31
FIGURE 11 ALGINATES TO DOMINATE THE EUROPEAN LIVE CELL ENCAPSULATION MARKET DURING THE FORECAST PERIOD 32
FIGURE 12 SIMPLE DRIPPING SEGMENT TO DOMINATE THE LIVE CELL ENCAPSULATION MARKET DURING THE FORECAST PERIOD 33
FIGURE 13 NORTH AMERICA WILL DOMINATE THE LIVE CELL ENCAPSULATION APPLICATION MARKET IN 2018 34
FIGURE 14 US AND GERMANY TO BE THE FASTEST-GROWING MARKETS FOR LIVE CELL ENCAPSULATION 35
FIGURE 15 LIVE CELL ENCAPSULATION MARKET: DRIVERS, RESTRAINTS, OPPORTUNITIES, AND CHALLENGES 36
FIGURE 16 SIMPLE DRIPPING SEGMENT TO DOMINATE THE LIVE CELL ENCAPSULATION MARKET DURING THE FORECAST PERIOD 43
FIGURE 17 ALGINATE SEGMENT TO DOMINATE THE LIVE CELL ENCAPSULATION MARKET DURING THE FORECAST PERIOD 56
FIGURE 18 DRUG DELIVERY SEGMENT TO DOMINATE THE LIVE CELL ENCAPSULATION MARKET DURING THE FORECAST PERIOD 65
FIGURE 19 NORTH AMERICA: LIVE CELL ENCAPSULATION MARKET SNAPSHOT 75
FIGURE 20 EUROPE: LIVE CELL ENCAPSULATION MARKET SNAPSHOT 81
FIGURE 21 ASIA PACIFIC: LIVE CELL ENCAPSULATION MARKET SNAPSHOT 89
FIGURE 22 LATIN AMERICA: LIVE CELL ENCAPSULATION MARKET SNAPSHOT 96
FIGURE 23 MEA: LIVE CELL ENCAPSULATION MARKET SNAPSHOT 99
FIGURE 24 KEY DEVELOPMENTS IN THE LIVE CELL ENCAPSULATION MARKET FROM
2014 TO 2018 102
FIGURE 25 BIOTIME, INC HELD THE LEADING POSITION IN THE LIVE CELL ENCAPSULATION MARKET IN 2017 103
FIGURE 26 COMPETITIVE LEADERSHIP MAPPING (2017) 107
FIGURE 27 BALCHEM CORPORATION: COMPANY SNAPSHOT (2017) 108
FIGURE 28 BIOTIME, INC.: COMPANY SNAPSHOT (2017) 110
FIGURE 29 EVONIK INDUSTRIES: COMPANY SNAPSHOT (2017) 116
FIGURE 30 LIVING CELL TECHNOLOGIES: COMPANY SNAPSHOT (2017) 118
FIGURE 31 MERCK KGAA: COMPANY SNAPSHOT (2017) 120

 

List of Tables



TABLE 1 LIVE CELL ENCAPSULATION MARKET, BY TECHNIQUE, 2017–2024 (USD MILLION) 42
TABLE 2 LIVE CELL ENCAPSULATION MARKET FOR SIMPLE DRIPPING, BY REGION 2017–2024 (USD MILLION) 44
TABLE 3 LIVE CELL ENCAPSULATION MARKET FOR SIMPLE DRIPPING, BY APPLICATION, 2017–2024 (USD MILLION) 44
TABLE 4 LIVE CELL ENCAPSULATION MARKET FOR ELECTROSTATIC DRIPPING, BY REGION, 2017–2024 (USD MILLION) 45
TABLE 5 LIVE CELL ENCAPSULATION MARKET FOR ELECTROSTATIC DRIPPING BY APPLICATION, 2017–2024 (USD MILLION) 46
TABLE 6 LIVE CELL ENCAPSULATION MARKET FOR COAXIAL AIRFLOW, BY REGION 2017–2024 (USD MILLION) 46
TABLE 7 LIVE CELL ENCAPSULATION MARKET FOR COAXIAL AIRFLOW, BY APPLICATION, 2017–2024 (USD MILLION) 47
TABLE 8 LIVE CELL ENCAPSULATION MARKET FOR LIQUID-JET BREAK-UP, BY REGION, 2017–2024 (USD MILLION) 48
TABLE 9 LIVE CELL ENCAPSULATION MARKET FOR LIQUID-JET BREAK-UP, BY APPLICATION, 2017–2024 (USD MILLION) 48
TABLE 10 LIVE CELL ENCAPSULATION MARKET FOR VIBRATING-JET TECHNIQUE, BY REGION, 2017–2024 (USD MILLION) 49
TABLE 11 LIVE CELL ENCAPSULATION MARKET FOR VIBRATING-JET TECHNIQUE BY APPLICATION, 2017–2024 (USD MILLION) 50
TABLE 12 LIVE CELL ENCAPSULATION MARKET FOR JET CUTTING, BY REGION 2017–2024 (USD MILLION) 51
TABLE 13 LIVE CELL ENCAPSULATION MARKET FOR JET CUTTING, BY APPLICATION 2017–2024 (USD MILLION) 51
TABLE 14 LIVE CELL ENCAPSULATION MARKET FOR ROTATING DISK ATOMIZATION BY REGION, 2017–2024 (USD MILLION) 52
TABLE 15 LIVE CELL ENCAPSULATION MARKET FOR ROTATING DISK ATOMIZATION BY APPLICATION, 2017–2024 (USD MILLION) 53
TABLE 16 LIVE CELL ENCAPSULATION MARKET, BY POLYMER TYPE 2017–2024 (USD MILLION) 55
TABLE 17 LIVE CELL ENCAPSULATION MARKET FOR ALGINATE, BY REGION 2017–2024 (USD MILLION) 57
TABLE 18 LIVE CELL ENCAPSULATION MARKET FOR HEMA-MMA, BY REGION 2017–2024 (USD MILLION) 58
TABLE 19 LIVE CELL ENCAPSULATION MARKET FOR CHITOSAN, BY REGION 2017–2024 (USD MILLION) 59
TABLE 20 LIVE CELL ENCAPSULATION MARKET FOR SILICEOUS ENCAPSULATES, BY REGION, 2017–2024 (USD MILLION) 60
TABLE 21 LIVE CELL ENCAPSULATION MARKET FOR CELLULOSE SULFATE, BY REGION, 2017–2024 (USD MILLION) 61
TABLE 22 LIVE CELL ENCAPSULATION MARKET FOR PAN-PVC, BY REGION 2017–2024 (USD MILLION) 62
TABLE 23 LIVE CELL ENCAPSULATION MARKET FOR OTHER POLYMERS, BY REGION 2017–2024 (USD MILLION) 63
TABLE 24 LIVE CELL ENCAPSULATION MARKET, BY APPLICATION 2017–2024 (USD MILLION) 65
TABLE 25 LIVE CELL ENCAPSULATION MARKET FOR DRUG DELIVERY, BY REGION 2017–2024 (USD MILLION) 66
TABLE 26 LIVE CELL ENCAPSULATION MARKET FOR REGENERATIVE MEDICINE BY REGION, 2017–2024 (USD MILLION) 67
TABLE 27 LIVE CELL ENCAPSULATION MARKET FOR CELL TRANSPLANTATION BY REGION, 2017–2024 (USD MILLION) 68
TABLE 28 LIVE CELL ENCAPSULATION MARKET FOR PROBIOTICS, BY REGION 2017–2024 (USD MILLION) 69
TABLE 29 LIVE CELL ENCAPSULATION MARKET FOR RESEARCH, BY REGION 2017–2024 (USD MILLION) 71
TABLE 30 LIVE CELL ENCAPSULATION MARKET, BY REGION, 2017–2024 (USD MILLION) 73
TABLE 31 LIVE CELL ENCAPSULATION MARKET, BY COUNTRY, 2017–2024 (USD MILLION) 74
TABLE 32 NORTH AMERICA: LIVE CELL ENCAPSULATION MARKET, BY COUNTRY 2017–2024 (USD MILLION) 76
TABLE 33 NORTH AMERICA: LIVE CELL ENCAPSULATION MARKET FOR SIMPLE DRIPPING BY COUNTRY, 2017–2024 (USD MILLION) 76
TABLE 34 NORTH AMERICA: LIVE CELL ENCAPSULATION MARKET, BY TECHNIQUE 2017–2024 (USD MILLION) 77
TABLE 35 NORTH AMERICA: LIVE CELL ENCAPSULATION MARKET, BY POLYMER TYPE 2017–2024 (USD MILLION) 77
TABLE 36 NORTH AMERICA: LIVE CELL ENCAPSULATION MARKET, BY APPLICATION 2017–2024 (USD MILLION) 78
TABLE 37 US: LIVE CELL ENCAPSULATION MARKET, BY TECHNIQUE 2017–2024 (USD MILLION) 79
TABLE 38 CANADA: LIVE CELL ENCAPSULATION MARKET, BY TECHNIQUE 2017–2024 (USD MILLION) 80
TABLE 39 EUROPE: LIVE CELL ENCAPSULATION MARKET, BY COUNTRY 2017–2024 (USD MILLION) 82
TABLE 40 EUROPE: LIVE CELL ENCAPSULATION MARKET, BY TECHNIQUE 2017–2024 (USD MILLION) 82
TABLE 41 EUROPE: LIVE CELL ENCAPSULATION MARKET, BY POLYMER TYPE 2017–2024 (USD MILLION) 83
TABLE 42 EUROPE: LIVE CELL ENCAPSULATION MARKET, BY APPLICATION 2017–2024 (USD MILLION) 83
TABLE 43 GERMANY: LIVE CELL ENCAPSULATION MARKET, BY TECHNIQUE 2017–2024 (USD MILLION) 84
TABLE 44 UK: LIVE CELL ENCAPSULATION MARKET, BY TECHNIQUE 2017–2024 (USD MILLION) 85
TABLE 45 FRANCE: LIVE CELL ENCAPSULATION MARKET, BY TECHNIQUE 2017–2024 (USD MILLION) 86
TABLE 46 ROE: LIVE CELL ENCAPSULATION MARKET, BY TECHNIQUE 2017–2024 (USD MILLION) 87
TABLE 47 ASIA PACIFIC: LIVE CELL ENCAPSULATION MARKET, BY COUNTRY 2017–2024 (USD MILLION) 90
TABLE 48 ASIA PACIFIC: LIVE CELL ENCAPSULATION MARKET, BY TECHNIQUE 2017–2024 (USD MILLION) 90
TABLE 49 ASIA PACIFIC: LIVE CELL ENCAPSULATION MARKET, BY POLYMER TYPE 2017–2024 (USD MILLION) 91
TABLE 50 ASIA PACIFIC: LIVE CELL ENCAPSULATION MARKET, BY APPLICATION 2017–2024 (USD MILLION) 91
TABLE 51 JAPAN: LIVE CELL ENCAPSULATION MARKET, BY TECHNIQUE 2017–2024 (USD MILLION) 92
TABLE 52 CHINA: LIVE CELL ENCAPSULATION MARKET, BY TECHNIQUE 2017–2024 (USD MILLION) 93
TABLE 53 INDIA: LIVE CELL ENCAPSULATION MARKET, BY TECHNIQUE 2017–2024 (USD MILLION) 94
TABLE 54 ROAPAC: LIVE CELL ENCAPSULATION MARKET, BY TECHNIQUE 2017–2024 (USD MILLION) 95
TABLE 55 LATIN AMERICA: LIVE CELL ENCAPSULATION MARKET, BY TECHNIQUE 2017–2024 (USD MILLION) 97
TABLE 56 LATIN AMERICA: LIVE CELL ENCAPSULATION MARKET, BY POLYMER TYPE 2017–2024 (USD MILLION) 97
TABLE 57 LATIN AMERICA: LIVE CELL ENCAPSULATION MARKET, BY APPLICATION 2017–2024 (USD MILLION) 98
TABLE 58 MEA: LIVE CELL ENCAPSULATION MARKET, BY TECHNIQUE 2017–2024 (USD MILLION) 100
TABLE 59 MEA: LIVE CELL ENCAPSULATION MARKET, BY POLYMER TYPE 2017–2024 (USD MILLION) 100
TABLE 60 MEA: LIVE CELL ENCAPSULATION MARKET, BY APPLICATION 2017–2024 (USD MILLION) 101
TABLE 61 KEY PRODUCT LAUNCHES 104
TABLE 62 KEY EXPANSIONS 104
TABLE 63 KEY ACQUISITIONS 105
TABLE 64 KEY PARTNERSHIPS, AGREEMENTS, AND COLLABORATIONS 105