Both NASH and NAFLD occur largely as a result of prolonged insulin resistance and obesity with approximately 80% of cases being diagnosed in overweight individuals. NASH is a severe form of NAFLD and is likely to become even more of a healthcare burden than it is at present. NASH can lead to liver cirrhosis and ultimately liver failure, which can be fatal if it is not treated quickly.

There are a total of 195 pipeline products in development for NASH and 65 products in development for NAFLD. Across the therapy area there are 158 companies developing products for NASH and 57 companies developing products for NAFLD. Key companies active in this space include Gilead, Novartis and Pfizer.

This report “Non Alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatitis (NASH) Drug Development Pipeline Review, 2018” provides an overview of the pipeline for non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). The report provides comprehensive information on the therapeutics under development and key players active in this space, and features dormant and discontinued projects.


  • Which companies are the most active within the pipeline for NAFLD and NASH therapeutics?
  • Which pharmaceutical approaches are most prominent at each stage of the pipeline and within each indication?
  • To what extent do universities and institutions play a role within this pipeline, compared to pharmaceutical companies?
  • What are the most important R&D milestones and data publications to have happened within this field?

Reasons To Buy

  • Understand the overall pipeline, with an at-a-glance overview of all products in therapeutic development for each indication
  • Assess the products in development in granular detail, with an up-to-date overview of each individual pipeline program in each indication, and a comprehensive picture of recent updates and milestones for each
  • Analyze the companies, institutions and universities currently operating in the pipeline, and the products being fielded by each of these
  • Understand the composition of the pipeline in terms of molecule type, molecular target, mechanism of action and route of administration