Table of Content

1 Market Guides 
1.1 Situation Analysis - COVID & Sepsis
1.2 Guide for Executives and Marketing Staff 
1.3 Guide for Investment Analysts and Management Consultants 

2 Introduction and Market Definition 
2.1 An Overview of Sepsis Diagnostics 
2.1.1 Sepsis the medical emergency
2.1.2 Sepsis Diagnosis and Comorbidity 
2.2 Market Definition 
2.2.1 Market Size 
2.2.2 Currency 
2.2.3 Years 
2.2.4 Microbiology 
2.2.5 PCR
2.2.6 Immunoassay 
2.2.7 Other Infectious Disease 
2.2.8 Syndromic PoC 
2.2.9 Biomarkers Molecular Diagnostics 
2.2.10 Biomarkers Other
2.2.11 Limitations 
2.3 Methodology 
2.3.1 Authors
2.3.2 Sources 
2.4 U.S. Medical Market and laboratory Testing - Perspective
2.4.1 U.S. Medicare Expenditures for Laboratory Testing 

3 Sepsis - Current Science 
3.1 What is Sepsis? 
3.1.1 Organ Damage 
3.1.2 Neonatal sepsis 
3.1.3 Prognosis 
3.2 Diagnosis 
3.2.1 Infection Identification 
3.2.2 Biomarkers 
3.2.3 Differential diagnosis 
3.2.4 The Cytokine Storm - Diagnostic Needs 
3.3 Causes of Sepsis 
3.3.1 Sepsis Progression 
3.3.2 The Cytokine Storm - COVID and Other Situations 
3.4 Prevalence
3.4.1 Impact of COVID on Sepsis Prevalence

4 Industry Overview 
4.1 Players in a Dynamic Market 
4.1.1 Academic Research Lab
4.1.2 Diagnostic Test Developer 
4.1.3 Pharmaceutical/Reagent Supplier
4.1.4 Independent Testing Lab
4.1.5 Public National/Regional Lab
4.1.6 Hospital lab
4.1.7 Physician Lab 
4.1.8 Audit Body 
4.1.9 Certification Body

5 Market Trends
5.1 Factors Driving Growth 
5.1.1 Increasing Prevalence 
5.1.2 Antimicrobial Resistance
5.1.3 Increasing Diagnosis
5.1.4 Multiplex Diagnostics Impacts 
5.1.5 The Aging World 
5.1.6 COVID Market Impact 
5.2 Factors Limiting Growth 
5.2.1 The Cost Curve Shrinks the Market
5.2.2 The Diagnostics Dillemma 
5.2.3 Adoption Lag and Cost Control 
5.3 Diagnostic Technology Development 
5.3.1 The Multiplex Opportunity
5.3.2 Shifting Role of Physicians in Diagnosis 
5.3.3 Diagnostics Moves Out of the Lab
5.3.4 Biomarkers and Algorithms 
5.3.5 Rapid Testing Changing Medical Practice
5.3.6 Genome Role and Big Data
5.3.7 The Next Five Years 

6 Sepsis Diagnostics - Recent Developments
6.1 Recent Developments - Importance and How to Use This Section 
6.1.1 Importance of These Developments 
6.1.2 How to Use This Section 
6.2 Study Establishes Cytovale IntelliSep Test for Rapid Diagnosis of Sepsis 
6.3 Baebies Awarded $11.6M to Develop Diagnostic Platform to ID Sepsis 
6.4 Personalized Medicine in Sepsis
6.5 Point-of-care Device can Diagnose Sepsis in 30 Minutes 
6.6 SpeeDx Developing Respiratory Virus Host-Response Test
6.7 Scanogen Developing Blood Infection Test with Sepsis Application
6.8 Inflammatix Moving Into COVID Test Market and Developing New Sepsis Dx 
6.9 Immunexpress, Biocartis to Roll Out Sepsis Test 
6.10 Sepset Biosciences Using COVID-19 Patient Samples to Validate Sepsis Test 
6.11 Immunexpress to Develop Sepsis Test for Coronavirus Patient Triage 
6.12 DNAe Developing POC Sequencing Platform for Coronavirus, Sepsis
6.13 NGS technique offers quick, accurate diagnosis of Sepsis
6.14 Portable device diagnoses sepsis faster 
6.15 Ontera and QuantuMDx Collaborate to Advance Sepsis Diagnosis 
6.16 Blood Test Accurately Predicts Sepsis Severity 
6.17 Sepsis diagnostics: HHS to advance development of Cytovale rapid test 
6.18 Mologic Developing Sepsis Test Using Multimarker
6.19 Abionic: Study Demonstrates Diagnosis of Sepsis in 5 Minutes 
6.20 T2 Biosystems Introduces New Data and Updates for Rapid Diagnostic Technology 
6.21 Sepsis found to fit into 4 Subtypes 
6.22 GenMark Diagnostics Receives FDA Clearance for Blood Panel
6.23 Novacyt, Immunexpress Extend Sepsis Assay Development Partnership
6.24 New Test Could Diagnose Sepsis Faster 
6.25 Immunexpress Wins $745K HHS Contract for Rapid Sepsis Assay 
6.26 Curetis’ Unyvero Application Cartridges Receive Regulatory Approvals 
6.27 Luminex Buys MilliporeSigma's Flow Cytometry Portfolio 
6.28 Experimental 2.5-minute Sepsis Test Discovered 
6.29 sphingotec raises €20 million 
6.30 SeLux Diagnostics Announces Sepsi U.S. HHS/BARDA Research Funding 
6.31 Roche PCT assay cleared as tool in fight against Sepsis
6.32 GeneFluidics selected as finalist for AMR Challenge 
6.33 BioDirection, Inc. Announces System to Diagnose and Monitor Sepsis
6.34 sphingotec Adding Advanced POC Testing Platform 
6.35 Rapid Detection Using DNAe’s LiDia® Bloodstream Infection Technology 
6.36 Septec Team Working on 15 Minute Sepsis Diagnosis 
6.37 Abionic Announces Rapid Sepsis PoC Diagnostic 

7 Profiles of Key Companies 
7.1 Abbott Diagnostics 
7.2 Abionic 
7.3 Accel Diagnostics 
7.4 Accelerate Diagnostics 
7.5 Axis-Shield Diagnostics Ltd
7.6 Beckman Coulter Diagnostics 
7.7 Becton, Dickinson and Company 
7.8 Biocartis 
7.9 bioMérieux Diagnostics
7.10 Bio-Rad Laboratories, Inc. 
7.11 Bruker 
7.12 Cube Dx 
7.13 Curetis N.V. / Curetis GmbH 
7.14 Cytovale
7.15 DNAe 
7.16 EKF Diagnostics Holdings 
7.17 GeneFluidics 
7.18 GenMark Dx 
7.19 Grifols 
7.20 Immunexpress 
7.21 Inflammatix 
7.22 LightDeck Diagnostics 
7.23 Linear Diagnostics 
7.24 Luminex Corp
7.25 Mbio Diagnostics 
7.26 Mobidiag
7.27 Nanomix 
7.28 Qiagen Gmbh 
7.29 Response Biomedical 
7.30 Roche Molecular Diagnostics 
7.31 SeLux Diagnostics 
7.32 Septec 
7.33 Siemens Healthineers 
7.34 Sphingotec
7.35 T2 Biosystems
7.36 Thermo Fisher Scientific Inc

8 Sepsis Global Diagnostic Markets Overview
8.1 Sepsis Diagnostics - Global Market Overview by Country 
8.1.1 Table - Global Market by Country
8.1.2 Chart - Global Market by Country 
8.2 Global Sepsis Diagnostics Markets Overview by Assay 
8.2.1 Table - Global Market by Assay
8.2.2 Chart - Global Market by Assay - Segments Growth
8.2.3 Chart - Global Market by Assay - Share by Year 
8.2.4 Chart - Global Market by Assay 
8.2.5 Chart - Global Market by Assay - Base Year 
8.2.6 Chart - Global Market by Assay - Final Year
8.3 Global Sepsis Diagnostics Markets Overview by Cause 
8.3.1 Table - Global Market by Cause 
8.3.2 Chart - Global Market by Cause - Segments Growth 
8.3.3 Chart - Global Market by Cause - Share by Year 
8.3.4 Chart - Global Market by Cause 
8.3.5 Chart - Global Market by Cause - Base Year 
8.3.6 Chart - Global Market by Cause - Final Year 
8.4 Global Sepsis Diagnostics Markets Overview by Product 
8.4.1 Table - Global Market by Product
8.4.2 Chart - Global Market by Product - Segments Growth
8.4.3 Chart - Global Market by Product - Share by Year
8.4.4 Chart - Global Market by Product
8.4.5 Chart - Global Market by Product - Base Year 
8.4.6 Chart - Global Market by Product - Final Year 
8.5 Global Sepsis Diagnostics Markets Overview by Lab 
8.5.1 Table - Global Market by Lab 
8.5.2 Chart - Global Market by Lab - Segments Growth 
8.5.3 Chart - Global Market by Lab - Share by Year
8.5.4 Chart - Global Market by Lab
8.5.5 Chart - Global Market by Lab - Base Year
8.5.6 Chart - Global Market by Lab - Final Year 
8.6 Global Sepsis Diagnostics Markets Overview by Place
8.6.1 Table - Global Market by Place
8.6.2 Chart - Global Market by Place - Segments Growth
8.6.3 Chart - Global Market by Place - Share by Year 
8.6.4 Chart - Global Market by Place 
8.6.5 Chart - Global Market by Place - Base Year 
8.6.6 Chart - Global Market by Place - Final Year

9 Sepsis Diagnostic Market - by Assay 
9.1 Sepsis Diagnostic - Microbiology 
9.1.1 Table Sepsis Diagnostic Microbiology - by Country
9.1.2 Chart - Sepsis Diagnostic Microbiology Growth 
9.2 Sepsis Diagnostic - PCR
9.2.1 Table Sepsis Diagnostic PCR - by Country 
9.2.2 Chart - Sepsis Diagnostic PCR Growth 
9.3 Sepsis Diagnostic - Immunoassay 
9.3.1 Table Sepsis Diagnostic Immunoassay - by Country
9.3.2 Chart - Sepsis Diagnostic - Immunoassay Growth 
9.4 Sepsis Diagnostic - Infectious Disease Other
9.4.1 Table Sepsis Diagnostic Infectious Disease Other - by Country 
9.4.2 Chart - Sepsis Diagnostic - Infectious Disease Other Growth 
9.5 Sepsis Diagnostic - Biomarker MDx 
9.5.1 Table Sepsis Diagnostic Biomarker MDx - by Country 
9.5.2 Chart - Sepsis Diagnostic - Biomarker MDx Growth 
9.6 Sepsis Diagnostic - Biomarker Other 
9.6.1 Table Sepsis Diagnostic Biomarker Other - by Country 
9.6.2 Chart - Sepsis Diagnostic - Biomarker Other Growth

10 Global Sepsis Diagnostics Markets - By Cause 
10.1 Sepsis Diagnostic - GastroIntestinal 
10.1.1 Table Sepsis Diagnostic GastroIntestinal - by Country
10.1.2 Chart - Sepsis Diagnostic GastroIntestinal Growth 
10.2 Sepsis Diagnostic - Respiratory COVID-19 
10.2.1 Table Sepsis Diagnostic Respiratory COVID-19- by Country 
10.2.2 Chart - Sepsis Diagnostic Respiratory COVID-19
10.3 Sepsis Diagnostic - Respiratory Other 
10.3.1 Table Sepsis Diagnostic Respiratory Other - by Country
10.3.2 Chart - Sepsis Diagnostic - Respiratory Other Growth 
10.4 Sepsis Diagnostic - Neonatal 
10.4.1 Table Sepsis Diagnostic Neonatal - by Country 
10.4.2 Chart - Sepsis Diagnostic - Neonatal Growth 
10.5 Sepsis Diagnostic - Other Cause 
10.5.1 Table Sepsis Diagnostic Other Cause - by Country
10.5.2 Chart - Sepsis Diagnostic - Other Cause Growth 

11 Global Sepsis Diagnostics Markets - By Product
11.1 Sepsis Diagnostic - Instrumentation 
11.1.1 Table Sepsis Diagnostic Instrumentation - by Country
11.1.2 Chart - Sepsis Diagnostic Instrumentation Growth 
11.2 Sepsis Diagnostic - Consumables
11.2.1 Table Sepsis Diagnostic Consumables - by Country 
11.2.2 Chart - Sepsis Diagnostic Consumables 
11.3 Sepsis Diagnostic - Software & Service
11.3.1 Table Sepsis Diagnostic Software & Service - by Country 
11.3.2 Chart - Sepsis Diagnostic - Software & Service Growth

12 Global Sepsis Diagnostics Markets - By Lab
12.1 Sepsis Diagnostic - In Lab
12.1.1 Table Sepsis Diagnostic In Lab - by Country 
12.1.2 Chart - Sepsis Diagnostic In Lab Growth
12.2 Sepsis Diagnostic - Point of Care
12.2.1 Table Sepsis Diagnostic Point of Care - by Country
12.2.2 Chart - Sepsis Diagnostic Point of Care 

13 Global Sepsis Diagnostics Markets - By Place 
13.1 Sepsis Diagnostic - Hospital 
13.1.1 Table Sepsis Diagnostic Hospital - by Country 
13.1.2 Chart - Sepsis Diagnostic Hospital Growth 
13.2 Sepsis Diagnostic - Other Place 
13.2.1 Table Sepsis Diagnostic Other Place - by Country
13.2.2 Chart - Sepsis Diagnostic Other Place

14 Appendices
14.1 United States Medicare System: 2021 Clinical Laboratory Fees Schedule

List of Tables
Table 1 Lab Spending 2014 to 2024 
Table 2 sepsis biomarkers - Established and potential
Table 3 Market Players by Type
Table 4 Five Factors Driving Growth 
Table 5 Three Factors Limiting Growth
Table 6 Global Sepsis Diagnostics Market by Country/Region
Table 7 Global Market by Assay 
Table 8 Global Market by Cause
Table 9 Global Market by Product 
Table 10 Global Market by Lab
Table 11 Global Market by Place 
Table 12 Sepsis Diagnostic Microbiology by Country 
Table 13 Sepsis Diagnostic PCR by Country
Table 14 Sepsis Diagnostic Immunoassay by Country 
Table 15 Sepsis Diagnostic Infectious Disease Other by Country 
Table 16 Sepsis Diagnostic Biomarker MDx by Country 
Table 17 Sepsis Diagnostic Biomarker Other by Country 
Table 18 Sepsis Diagnostic GastroIntestinal by Country 
Table 19 Sepsis Diagnostic Respiratory COVID-19 by Country
Table 20 Sepsis Diagnostic Respiratory Other by Country 
Table 21 Sepsis Diagnostic Neonatal by Country
Table 22 Sepsis Diagnostic Other Cause by Country
Table 27 Sepsis Diagnostic Instrumentation by Country 
Table 28 Sepsis Diagnostic Consumables by Country 
Table 29 Sepsis Diagnostic Software & Service by Country 
Table 30 Sepsis Diagnostic In Lab by Country 
Table 31 Sepsis Diagnostic Point of Care by Country 
Table 32 Sepsis Diagnostic Hospital by Country 
Table 33 Sepsis Diagnostic Other Place by Country 
Table 34 2021 Clinical Lab Fee Schedule

List of Figures
Figure 1 Sepsis Survival graph 
Figure 2 Percentage of Sepsis Patients with Comorbidity 
Figure 3 Clinical Lab Spending 2014 to 2024 
Figure 4 Sepsis Clinical Progression 
Figure 5 Deaths From Drug Resistant Infections 2050 
Figure 6 Aggregate Age of World Population
Figure 7 Growth in Health Care Spending Developing World 
Figure 8 Comparing The New Diagnostics and Traditional Testing 
Figure 9 Growth rates of Sepsis Diagnostics 
Figure 10 Global Market Share Chart 
Figure 11 Sepsis Diagnostics Market Segment Shift Base vs Final year 
Figure 12 Sepsis Diagnostics Market by Assay Base Year 
Figure 13 Sepsis Diagnostics Market by Assay Final Year
Figure 14 Sepsis Diagnostics Market Segment Shift Base vs Final year 
Figure 15 Sepsis Diagnostics Market by Cause Base Year 
Figure 16 Sepsis Diagnostics Market by Cause Final Year 
Figure 17 Sepsis Diagnostics Market Segment Shift Base vs Final year 
Figure 18 Sepsis Diagnostics Market by Product Base Year 
Figure 19 Sepsis Diagnostics Market by Product Final Year 
Figure 20 Sepsis Diagnostics Market Segment Shift Base vs Final year 
Figure 21 Sepsis Diagnostics Market by Lab Base Year 
Figure 22 Sepsis Diagnostics Market by Lab Final Year 
Figure 23 Sepsis Diagnostics Market Segment Shift Base vs Final year
Figure 24 Sepsis Diagnostics Market by Place Base Year 
Figure 25 Sepsis Diagnostics Market by Place Final Year
Figure 26 Sepsis Diagnostic Microbiology Growth 
Figure 27 SEPSIS Diagnostics Syndromic POC Panel Growth
Figure 28 Sepsis Diagnostic Immunoassay Growth 
Figure 29 Sepsis Diagnostic Infectious Disease Other Growth 
Figure 30 Sepsis Diagnostic Biomarker MDx Growth 
Figure 31 Sepsis Diagnostic Biomarker Other Growth 
Figure 32 Sepsis Diagnostic GastroIntestinal Growth 
Figure 33 SEPSIS Diagnostics Respiratory COVID-19 
Figure 34 Sepsis Diagnostic Respiratory Other Growth 
Figure 35 Sepsis Diagnostic Neonatal Growth 
Figure 36 Sepsis Diagnostic Other Cause Growth 
Figure 41 Sepsis Diagnostic Instrumentation Growth 
Figure 42 SEPSIS Diagnostics Consumables 
Figure 43 Sepsis Diagnostic Software & Service Growth
Figure 44 Sepsis Diagnostic In Lab Growth
Figure 45 SEPSIS Diagnostics Point of Care
Figure 46 Sepsis Diagnostic GastroIntestinal Growth 
Figure 47 SEPSIS Diagnostics Other Place