Table of Content

1. Market Overview

1.1 Introduction
1.2 CAR-T Cell Design
1.3 Process of T-Cell Therapy
1.4 Autologous vs. Allogeneic CAR-T cell therapy
1.5 Mechanism of Action
1.6 Toxicity Related to CAR-T Cell Therapy
1.7 FDA Approved CAR-T Cell Therapy
1.8 CAR-T Cell Therapies under Development


2. Global Market Analysis

2.1 Global CAR-T Cell Market Forecast by Value
2.2 Number of CAR-T Cell Clinical Trials
2.3 Number of Clinical Trials Targeting Hematologic Malignancies by Antigens
2.4 Number of Clinical Trials Targeting Solid Tumors by Antigens
2.5 Global CAR-T Cell Hematological Malignancy Market
2.5.1 Global CAR-T Cell Hematological Malignancy Market Share by Cancer Type
2.5.2 Global CAR-T Cell Hematological Malignancy Market Share Forecast by Cancer Type
2.5.3 Global CAR-T Cell ALL Market Forecast by Value
2.5.4 Global CAR-T Cell DLBCL Market Forecast by Value
2.5.5 Global CAR T Cell FL Market Forecast by Value
2.5.6 Global CAR-T Cell CLL Market Forecast by Value
2.5.7 Global CAR T Cell MM Market Forecast by Value
2.6 Global Kymriah Revenue Forecast
2.7 Global Yescarta Revenue Forecast
2.8 Global CYAD-01 AML Revenue Forecast
2.9 Global CYAD-01 mCRC Revenue Forecast


3. Regional Market Analysis

3.1 The U.S.
3.1.1 The U.S. ALL Patients Treated with UCART19 Forecast
3.1.2 The U.S. UCART19 Revenue Forecast
3.1.3 The U.S. DLBCL Patients Treated with ALLO-501 Forecast
3.1.4 The U.S. ALLO-501 Revenue Forecast
3.1.5 The U.S. Patients treated with CYAD-01 for AML Forecast
3.1.6 The U.S. CYAD-01 Revenue Forecast for AML
3.1.7 The U.S. Patients Treated with CYAD-01 for mCRC Forecast
3.1.8 The U.S. CYAD-01 Revenue for mCRC Forecast

3.2 Europe
3.2.1 Europe Patients Treated with CYAD-01 for AML Forecast
3.2.2 Europe CYAD-01 Revenue for AML Forecast
3.2.3 Europe Patients treated with CYAD-01 for mCRC Forecast
3.2.4 Europe CYAD-01 Revenue for mCRC Forecast

3.3 Japan
3.3.1 Japan Patients treated with CYAD-01 for AML Forecast
3.3.2 Japan CYAD-01 Revenue for AML Forecast
3.3.3 Japan Patients treated with CYAD-01 for mCRC Forecast
3.3.4 Japan CYAD-01 Revenue for mCRC Forecast


4. Market Dynamics

4.1 Growth Drivers
4.1.1 Growing Cancer Incidences Rates
4.1.2 Proven Effectiveness of T-cell Therapies
4.1.3 Increasing Number of Deals for CART cell Development
4.1.4 High Unmet Needs

4.2 Key Trends & Developments
4.2.1 Collaborative R&D
4.2.2 Reimbursements

4.3 Challenges
4.3.1 High Cost
4.3.2 Regulatory Standards
4.3.3 Safety Concerns


5. Competitive Landscape

5.1 Global Market
5.1.1 Revenue and Market Cap Comparison
5.1.2 Global CART Cell Therapies in AML under Development
5.1.3 Global CAR-T under Development for Metastatic Colorectal Cancer
5.1.4 Global BCMA CAR T Therapies in Clinical Trials for Multiple Myeloma
5.1.5 Global CD19 targeted CART products in Clinical Trials
5.1.6 Global CD19 targeted CART products in Clinical Trials for Adult ALL


6. Company Profiles

6.1 Bluebird Bio, Inc.
6.1.1 Business Overview
6.1.2 Financial Overview
6.1.3 Business Strategies

6.2 Celgene Corporation
6.2.1 Business Overview
6.2.2 Financial Overview
6.2.3 Business Strategies

6.3 Novartis International AG
6.3.1 Business Overview
6.3.2 Financial Overview
6.3.3 Business Strategies

6.4 Gilead Sciences
6.4.1 Business Overview
6.4.2 Financial Overview
6.4.3 Business Strategies



List of Figures



CAR-T Cell Formation
Mechanism of Car-T cell Therapy
Global CAR-T Cell Market Forecast by Value (2018-2023)
Number of CAR-T Cell Clinical Trials (2013-2017)
Number of Clinical Trials Targeting Hematologic Malignancies by Antigens (2017)
Number of Clinical Trials Targeting Solid Tumors by Antigens (2017)
Global CAR-T Cell Hematological Malignancy Market Forecast (2018-2023)
Global CAR-T Cell Hematological Malignancy Market Share by Cancer Type (2018)
Global CAR-T Cell Hematological Malignancy Market Share Forecast by Cancer Type (2023)
Global CAR-T Cell ALL Market Forecast by Value (2018-2023)
Global CAR-T Cell DLBCL Market Forecast by Value (2018-2023)
Global CAR T Cell FL Market Forecast by Value (2019-2023)
Global CAR T Cell CLL Market Forecast by Value (2019-2023)
Global CAR T Cell MM Market Forecast by Value (2019-2023)
Global Kymriah Revenue Forecast (2018-2023)
Global Yescarta Revenue Forecast (2018-2023)
Global CYAD-01 AML Revenue Forecast (2023-2028)
Global CYAD-01 mCRC Revenue Forecast (2024-2028)
The U.S. ALL Patients Treated with UCART19 Forecast (2018-2023)
The U.S. UCART19 Revenue Forecast (2023-2027)
The U.S. DLBCL Patients Treated with ALLO-501 Forecast (2018-2023)
The U.S. ALLO-501 Revenue Forecast (2023-2027)
The U.S. Patients treated with CYAD-01 for AML Forecast (2023-2028)
The U.S. CYAD-01 Revenue Forecast for AML (2023-2028)
The U.S. Patients Treated with CYAD-01 for mCRC Forecast (2024-2029)
The U.S. CYAD-01 Revenue for mCRC Forecast (2024-2028)
Europe Patients Treated with CYAD-01 for AML Forecast (2023-2028)
Europe CYAD-01 Revenue for AML Forecast (2023-2028)
Europe Patients treated with CYAD-01 for mCRC Forecast (2024-2028)
Europe CYAD-01 Revenue for mCRC Forecast (2024-2028)
Japan Patients treated with CYAD-01 for AML Forecast (2025-2028)
Japan CYAD-01 Revenue for AML Forecast (2025-2028)
Japan Patients treated with CYAD-01 for mCRC Forecast (2024-2028)
Japan CYAD-01 Revenue for mCRC Forecast (2024-2027)
Number of New Cancer Cases by Type (2018)
Clinical Outcomes of Trial Evaluating CAR-T Cells in Blood Cancers (2017)
Bluebird Bio, Inc. Product Pipeline (2018)
Bluebird Bio, Inc. Revenue and Net Loss (2014-2018)
Bluebird Bio, Inc. R&D Expenditure (2016-2018)
Celgene Corporation Revenue by Product Sales (2018)
Celgene Corporation Revenue and Net Income (2014-2018)
Celgene Corporation R&D Expenditure (2016-2018)
Novartis International AG Sales by Segment (2018)
Novartis Net Sales and Net Income (2014-2018)
Gilead Sciences Revenue by Geographical Region (2018)
Gilead Sciences Revenue and Net Income (2014-2018)
Gilead Sciences R&D Expenditure (2016-2018)

List of Tables



Comparison between Autologous and Allogeneic T-cell Therapy
Kymriah Developmental Program
Yescarta Developmental Program
Global CAR-T Cell Therapies under Development
Recent Acquisitions in CAR T cell Market (2018)
Recent Collaborations in CAR T cell Market (2018)
CAR-T Cell Treatment Costs (2018)
Key Players - Revenue & Market Cap Comparison (2018)
Global CART Cell Therapies in AML under Development (2018)
Global CAR-T under Development for Metastatic Colorectal Cancer (2018)
Global BCMA CAR T Therapies in Clinical Trials for Multiple Myeloma (2018)
Global CD19 targeted CART products in Clinical Trials (2018)
Global CD19 targeted CART products in Clinical Trials for Adult ALL (2018)